Saccharomyces boulardii

DRUG18 trials

Sponsors

Biocodex, Aga Khan University, Bernhard Nocht Institute for Tropical Medicine, Zekai Tahir Burak Women's Health Research and Education Hospital, Beth Israel Deaconess Medical Center

Conditions

Acute Watery DiarrheaAntibiotic Associated DiarrheaAntibiotic-associated DiarrheaClostridium DifficileColorectal CancerDiarrheaDiarrhea Dominant Irritable Bowel SyndromeGastroenteritis

Phase 2

Treatment of Patients With Human Immunodeficiency Virus (HIV)-Related Chronic Diarrhea With Saccharomyces Boulardii or Placebo: A Double Blind Trial

CompletedNCT00002088

BiocodexDiarrhea, HIV Infections

Target: 100Updated: 2005-06-24

A Pilot Study of Probiotic Saccharomyces Boulardii Use in Chronic Heart Failure Patients. Estudo PROICA

CompletedNCT01500343

Universidade Federal FluminenseHeart Failure

Start: 2008-11-30End: 2010-12-31Updated: 2011-12-28

Effect of Saccharomyces Boulardii in Patients in the Waiting List for Liver Transplant

CompletedNCT01762748

Federal University of Minas GeraisLiver Cirrhosis

Start: 2011-01-31End: 2012-12-31Updated: 2013-01-09

GutHeart: Targeting Gut Microbiota to Treat Heart Failure

Oslo University HospitalSystolic Heart Failure

Start: 2016-03-11End: 2019-12-31Target: 150Updated: 2019-03-26

Phase 3

Saccharomyces Boulardii in Irritable Bowel Syndrome

CompletedNCT00589771

Aga Khan UniversityDiarrhea Dominant Irritable Bowel Syndrome

Start: 2010-01-31End: 2011-12-31Updated: 2012-10-16

Probiotic Saccharomyces Boulardii for the Prevention of Antibiotic-associated Diarrhoea

TerminatedNCT01143272

Bernhard Nocht Institute for Tropical MedicineAntibiotic-associated Diarrhea, Clostridium Difficile, Diarrhea

Start: 2010-06-30End: 2012-10-31Updated: 2016-07-18

Effect of Saccharomyces Boulardii on Necrotizing Enterocolitis in Very Low Birth Weight Infants

Zekai Tahir Burak Women's Health Research and Education HospitalNecrotizing Enterocolitis, Very Low Birth Weight Infants

Start: 2011-02-28End: 2011-12-31Target: 220Updated: 2011-08-08

Phase 4

Saccharomyces Boulardii in Diarrhea Dominant Irritable Bowel Syndrome

Aga Khan UniversityIrritable Bowel Syndrome

Start: 2007-10-31End: 2008-07-31Target: 42Updated: 2007-10-15

Impact of Probiotics on the Intestinal Microbiota

CompletedNCT01609660

Federal University of Minas GeraisColorectal Cancer

Start: 2010-03-31End: 2013-03-31Updated: 2016-09-12

Assesment of the Efficiency and Safety Helicobacter Pylori Therapy With or Without Saccharomyces Boulardii

Clinical Centre of SerbiaHelicobacter Pylori Infection

Start: 2019-06-30End: 2020-06-30Target: 200Updated: 2019-06-25

Unknown Phase

Effects of Pre-, Pro- & Anti-biotics on Gut Microbiota

CompletedNCT01414010

Beth Israel Deaconess Medical CenterHuman Gut Microbiota

Start: 2011-08-31End: 2012-02-29Updated: 2017-07-24

Effects of S. Boulardii and Amoxicillin/Clavulanate on Gut Microbiota

CompletedNCT01473368

Beth Israel Deaconess Medical CenterHealthy Volunteers

Start: 2012-04-30End: 2013-02-28Updated: 2017-04-04

Impact of Probiotics in Modulation of Intestinal Microbiota

CompletedNCT01895530

Maria Isabel Toulson Davisson CorreiaColorectal Cancer

Start: 2010-07-31End: 2012-05-31Updated: 2013-07-10

Efficacy of Two Probiotic Preparations in Children With Acute Diarrhoea

WithdrawnNCT02080130

Sinaloa Pediatric HospitalGastroenteritis

Start: 2014-02-28End: 2016-12-31Updated: 2018-09-06

Evaluation of Saccharomyces Boulardii Combined With Standard Quadruple Therapy for Eradication of Helicobacter Pylori

CompletedNCT03688828

Huazhong University of Science and TechnologyHelicobacter Pylori Infection

Start: 2018-11-11End: 2020-12-31Updated: 2021-10-26

Comparison of Effectiveness of Zinc Supplementation With ORS and Bacillus Clausii Versus Zinc With ORS and Saccharomyces Boulardii in Acute Watery Diarrhea in Paediatric Patients

CompletedNCT06540209

RESnTEC, Institute of ResearchAcute Watery Diarrhea

Start: 2023-04-01End: 2023-09-30Updated: 2024-08-12

Efficacy Analysis of Saccharomyces Boulardii Combined With Minocycline in Treatment-naïve Patients With Helicobacter Pylori Infection

Not yet recruitingNCT07012785

Zhongda HospitalH. Pylori Infection

Start: 2025-06-30End: 2025-12-31Target: 208Updated: 2025-06-10

Effectiveness of Saccharomyces Boulardii in Prevention of Antibiotic Associated Diarrhea

Not yet recruitingNCT07785206

University of Child Health Sciences and Children's Hospital, LahoreAntibiotic Associated Diarrhea, Upper Respiratory Tract Infection

Start: 2026-09-01End: 2027-05-01Target: 88Updated: 2026-08-25

Related Papers

Microbial-derived imidazole propionate links the heart failure-associated microbiome alterations to disease severity.

2024-02-0826 citations

Saccharomyces boulardii Combined With Quadruple Therapy for Helicobacter pylori Eradication Decreased the Duration and Severity of Diarrhea: A Multi-Center Prospective Randomized Controlled Trial

Frontiers in Medicine2021-11-1833 citations

Saccharomyces boulardii CNCM I-745 Modulates the Fecal Bile Acids Metabolism During Antimicrobial Therapy in Healthy Volunteers

Frontiers in Microbiology2019-03-0127 citations

Saccharomyces boulardii to Prevent Antibiotic-Associated Diarrhea: A Randomized, Double-Masked, Placebo-Controlled Trial

Open Forum Infectious Diseases2016-01-0164 citations