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Intravenous Dexmedetomidine

DRUG18 trials

Sponsors

University of Turku, Yao Yusheng, University of Jordan, Assiut University, Mansoura University

Conditions

AnaesthesiaAnalgesiaAneurysm CerebralBariatric SurgeryCryptorchidismDeliriumDexmedetomidineEar, Nose and Throat

Phase 1

Bioavailability of Dexmedetomidine After Intranasal Administration
CompletedNCT00837187
University of TurkuSedation
Start: 2009-03-31End: 2009-05-31Updated: 2010-01-13
Safety, Pharmacokinetics and Pharmacodynamics of Intranasal Dexmedetomidine in Healthy Subjects
NCT03293277
Jiangsu HengRui Medicine Co., Ltd.Sedation
Start: 2017-07-26End: 2018-07-31Target: 48Updated: 2018-01-23

Phase 2

Caudal Versus Intravenous Dexmedetomidine for Supplementation of Caudal Analgesia in Children
CompletedNCT01701778
Yao YushengCryptorchidism, Inguinal Hernia
Start: 2012-10-31End: 2014-01-31Updated: 2018-11-15
Caudal Versus Intravenous Dexmedetomidine for Caudal Analgesia in Children
CompletedNCT02416063
University of JordanPain
Start: 2014-01-31End: 2014-10-31Updated: 2015-04-14
Efficacy of Dexmedetomidine for Postoperative Analgesia in Infantile Cataract Surgery
NCT02495220
Assiut UniversityPostoperative Pain, Postoperative Vomiting
Start: 2015-07-31End: 2017-11-30Target: 80Updated: 2017-01-27

Phase 3

Minimizing ICU Neurological Dysfunction With Dexmedetomidine-induced Sleep (MINDDS II)
RecruitingNCT06192615
Massachusetts General HospitalDelirium
Start: 2025-01-06End: 2029-03-31Target: 1800Updated: 2026-07-06

Phase 4

Intrathecal Versus Intravenous Dexmeditomedine in Transurethral Resection of the Prostate
NCT04618965
Tanta UniversityDexmedetomidine, Intrathecal, Intravenous +1
Start: 2020-11-01End: 2021-06-26Target: 75Updated: 2020-11-06
Intranasal Versus Intravenous Dexmedetomidine for Hypotensive Anesthesia in FESS
CompletedNCT05604599
Al-Azhar UniversityAnalgesia, Functional Endoscopic Sinus Surgery, Premedication
Start: 2022-11-10End: 2023-03-05Updated: 2023-03-14
Nasal Packing Versus Intravenous Dexmedetomidine in Turbinate Surgeries
CompletedNCT05911776
Kafrelsheikh UniversityDexmedetomidine, Nasal Packing, Turbinate
Start: 2023-06-30End: 2024-02-27Updated: 2024-03-12
Intranasal Dexmedetomidine Versus Intravenous Dexmedetomidine for Improving Quality of Endoscopic Sinus Surgery
NCT06081933
Kafrelsheikh UniversityDexmedetomidine, Functional Endoscopic Sinus
Start: 2022-12-20End: 2023-12-15Target: 54Updated: 2023-10-13
Comparative Effects of Intravenous Versus Intranasal Dexmedetomidine on Cardiac Function in Patients with Sepsis
Active, not recruitingPACTR202511730546627
Mostafa AliAnaesthesia
Start: 2025-11-01Target: 38Updated: 2026-06-22

Unknown Phase

Intra-articular Versus Intravenous Dexmedetomidine in Arthroscopic Knee Surgeries Under Local Anesthesia
CompletedNCT02730845
Mansoura UniversityKnee Arthroscopy
Start: 2015-12-01End: 2016-05-30Updated: 2020-09-22
Dexmedetomidine Improves Recovery After Cranial Aneurysm Surgery
CompletedNCT03355534
Zhihong LUAneurysm Cerebral
Start: 2018-01-05End: 2020-12-30Updated: 2022-05-26
Intravenous Versus Perineural Dexmedetomidine as Adjuvant in Adductor Canal Block for Total Knee Arthroplasty
CompletedNCT04266145
Mansoura UniversityPost Spinal Anesthesia Shivering
Start: 2020-02-29End: 2022-08-25Updated: 2022-08-29
Nebulized Versus Intravenous Dexmedetomidine for Sevoflurane Induced Emergence Agitation After Pediatric Tonsillectomy
NCT05641376
Assiut UniversityEmergence Agitation
Start: 2023-02-01End: 2023-12-01Target: 120Updated: 2023-04-25
Impact of Dexmedetomidine on bleeding during endoscopic sinus surgery
Active, not recruitingPACTR202512570526462
Assiut UniversityEar, Nose and Throat Surgery Anaesthesia
Start: 2026-01-01Target: 22Updated: 2026-06-22
Intravenous Lidocaine Infusion Versus Intravenous Dexmedetomidine Infusion During Sleeve Gastrectomy
RecruitingNCT07327905
Alexandria UniversityBariatric Surgery, Dexmedetomidine, Lidocaine
Start: 2025-12-26End: 2026-11-01Target: 40Updated: 2026-01-08
Comparison of intravenous versus nebulized dexmedetomidine on blood loss during functional endoscopic sinus surgery
Active, not recruitingPACTR202601692450392
Assiut UniversityEar, Nose and Throat
Start: 2026-01-01Target: 60Updated: 2026-06-22

Related Papers

Intra-articular versus intravenous administration of dexmedetomidine in arthroscopic knee surgeries under local anesthesia: A prospective randomized study
Egyptian Journal of Anaesthesia2017-12-131 citations