Ear, Nose and Throat Surgery Anaesthesia
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Patients undergoing endoscopic nasal surgeries for bilateral nasal polyposis Patients 18 years or older
Exclusion criteria
Exclusion criteria: Patients with bleeding or coagulation disorders History of using anticoagulant or antiplatelet medications within 2 weeks before surgery Uncontrolled hypertension Significant or unstable cardiovascular disease Known allergy/hypersensitivity to dexmedetomidine Severe hepatic or renal diseases Neurological or psychiatric disorders impairing consent or protocol adherence Advanced chronic respiratory disease Pregnancy or breastfeeding Complex sinonasal surgeries or combined surgical procedures History of sinus surgery in the last 3 months Refusal/inability to provide informed consent or comply with follow-up
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Total blood loss (ml) during functional endoscopic sinus surgery for each nasal side (with and without dexmedetomidine), determined by the combined weight of soaked gauze pads and the volume of blood suctioned, accounting for irrigation fluid. | — |
Secondary
| Measure | Time frame |
|---|---|
| Surgical field visibility score on a standard 3-point scale (good/moderate/poor) for each nasal side, surgeon satisfaction score (VAS 0–10), intraoperative hemodynamic variables (heart rate, mean arterial pressure, SpO2), and duration of surgery per nasal side. | — |
Countries
Egypt
Contacts
Assiut University