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Impact of Dexmedetomidine on bleeding during endoscopic sinus surgery

Impact of Dexmedetomidine on intraoperative bleeding during Functional Endoscopic Sinus Surgery: a prospective quasi-experimental self-controlled clinical study

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
PACTR
Registry ID
PACTR202512570526462
Enrollment
22
Registered
2025-12-02
Start date
2026-01-01
Completion date
Unknown
Last updated
2026-01-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Ear, Nose and Throat Surgery Anaesthesia

Interventions

No dexmedetomidine. standard care.

Sponsors

Assiut University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Patients undergoing endoscopic nasal surgeries for bilateral nasal polyposis Patients 18 years or older

Exclusion criteria

Exclusion criteria: Patients with bleeding or coagulation disorders History of using anticoagulant or antiplatelet medications within 2 weeks before surgery Uncontrolled hypertension Significant or unstable cardiovascular disease Known allergy/hypersensitivity to dexmedetomidine Severe hepatic or renal diseases Neurological or psychiatric disorders impairing consent or protocol adherence Advanced chronic respiratory disease Pregnancy or breastfeeding Complex sinonasal surgeries or combined surgical procedures History of sinus surgery in the last 3 months Refusal/inability to provide informed consent or comply with follow-up

Design outcomes

Primary

MeasureTime frame
Total blood loss (ml) during functional endoscopic sinus surgery for each nasal side (with and without dexmedetomidine), determined by the combined weight of soaked gauze pads and the volume of blood suctioned, accounting for irrigation fluid.

Secondary

MeasureTime frame
Surgical field visibility score on a standard 3-point scale (good/moderate/poor) for each nasal side, surgeon satisfaction score (VAS 0–10), intraoperative hemodynamic variables (heart rate, mean arterial pressure, SpO2), and duration of surgery per nasal side.

Countries

Egypt

Contacts

Public ContactHussein Elweshahy

Assiut University

Weshahy_orl@aun.edu.eg+201001775898

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Feb 4, 2026