placebo group:normal saline

8 trials

Sponsors

West China Hospital, Sichuan University, Xuzhou Medical University, Department of Pediatric, PLA General Hospital, Wuhan Infectious Diseases Hospital, Shenzhen People's Hospital

Conditions

COVID-19Congenital Heart DiseaseHepatic ischemia-reperfusion injuryLower respiratory infectious diseases [such as acute attack of chronic bronchitis, acute exacerbation of chronic obstructive pulmonary disease, bronchiectasis (mild columnar bronchiectasis without hemoptysis), pneumonia, acute bronchitis, etcPerioperative Respiratory Adverse EventsPostoperative deliriumdepressive statepreoperative sedation

Early Phase 1

Erythromycin versus mosaprid for post-pyloric nasoenteric tube placement in the pediatric critically ill patient: a randomized non-inferiority study

Active, not recruitingChiCTR2100047651

Department of Pediatric, PLA General HospitalCongenital Heart Disease

Start: 2021-06-21Updated: 2022-02-28

Phase 1

Phase I clinical study to evaluate the safety, tolerance and pharmacokinetics of nasal spray of recombinant human anti COVID-19 monoclonal antibody (F61 nasal spray) in Chinese healthy subjects with different doses of single and multiple nasal sprays

Active, not recruitingChiCTR2200066841

Wuhan Infectious Diseases HospitalCOVID-19

Start: 2022-12-19Updated: 2023-05-15

Phase 3

A confirmatory clinical trial of inhaled bromhexine hydrochloride solution for adult expectorant therapy

RecruitingChiCTR2500097308

Shenzhen People's HospitalLower respiratory infectious diseases [such as acute attack of chronic bronchitis, acute exacerbation of chronic obstructive pulmonary disease, bronchiectasis (mild columnar bronchiectasis without hemoptysis), pneumonia, acute bronchitis, etc

Start: 2023-04-24Updated: 2025-02-24

Phase 4

A prospective, double-blind, randomized controlled clinical trial for preventive use of ulinastatin on hepatic ischemia-reperfusion injury.

RecruitingChiCTR1900021546

West China Hospital, Sichuan UniversityHepatic ischemia-reperfusion injury

Start: 2019-11-22Updated: 2019-11-25

The effect of preoperative application of midazolam or dexmedetomidine on adverse events of the perioperative respiratory system in children undergoing tonsillectomy and adenoidectomy: a prospective, randomized, double-blinded, controlled study

RecruitingChiCTR2000038359

Xuzhou Medical UniversityPerioperative Respiratory Adverse Events

Start: 2020-10-01Updated: 2022-03-07

The influence of esketamine on perioperative depressive symptoms in children

RecruitingChiCTR2500107873

Beijing Children’s Hospital, Capital Medical Universitydepressive state

Start: 2025-09-01Updated: 2025-08-25

Effect of intraoperative remimazolam on postoperative delirium in older cancer patients undergoing major oncologic surgery

Active, not recruitingChiCTR2600122767

Chongqing University Cancer HospitalPostoperative delirium

Start: 2026-05-01Updated: 2026-04-27

Unknown Phase

Comparison of intranasal spray using midazolam, ketamine and dexmedetomidine for preoperative sedation in pediatric anesthesia

Active, not recruitingChiCTR-IOR-17013744

Shanghai Ninth People's Hospital, School Of Medicine, Shanghai Jiaotong Universitypreoperative sedation

Start: 2018-01-01Updated: 2017-12-11

Related Papers

Effect of Intranasal Dexmedetomidine or Midazolam for Premedication on the Occurrence of Respiratory Adverse Events in Children Undergoing Tonsillectomy and Adenoidectomy

JAMA Network Open2022-08-0978 citations