Ketone monoester

DIETARY_SUPPLEMENT13 trials

Sponsors

University of British Columbia, University of Aarhus, University of Alabama at Birmingham, McMaster University, Universidad Católica San Antonio de Murcia

Conditions

Appetite ControlBrain Insulin SensitivityBrain Vascular FunctionCerebral Blood FlowCognitive PerformanceCritical IllnessCystic FibrosisDietary Supplement: Ketone Supplement

Phase 1

Exogenous Ketones and Glucose Tolerance

CompletedNCT03461068

University of British ColumbiaDietary Supplements, Ketones

Start: 2018-03-26End: 2018-10-15Updated: 2019-04-18

The Effects of Exogenous Ketones on Glucose Tolerance

CompletedNCT04088617

University of British ColumbiaDietary Supplement: Ketone Supplement, Dietary Supplement: Placebo

Start: 2019-08-01End: 2020-01-05Updated: 2020-03-24

Exogenous Ketone Supplementation in ICU Delirium

Not yet recruitingNCT07364162

Vanderbilt University Medical CenterCritical Illness, ICU Delirium

Start: 2026-04-06End: 2027-12-31Target: 40Updated: 2026-03-31

Phase 2

Modulation of Circulating Levels of the Ketone Body 3-hydroxybutyrate in Patients With Chronic Heart Failure: Cardiovascular Effects

University of AarhusHeart Failure, Ketonemia, Ketosis

Start: 2019-04-25End: 2022-11-01Updated: 2022-08-18

Metabolic Effects of Chronic Ketosis (KETO-CHF Metabolic)

CompletedNCT05161676

University of AarhusHeart Failure

Start: 2021-12-15End: 2023-10-01Updated: 2023-11-30

Unknown Phase

Exogenous Ketones in Type 2 Diabetes

CompletedNCT04194450

University of British ColumbiaKetosis, Type 2 Diabetes

Start: 2020-01-15End: 2022-05-20Updated: 2025-05-30

Ketone Supplementation in Cystic Fibrosis

CompletedNCT04938726

University of Alabama at BirminghamCystic Fibrosis

Start: 2021-11-01End: 2023-04-30Updated: 2025-02-13

The Effects of Acute Ketone Monoester Supplementation on 20-Minute Time-Trial Performance in Trained Cyclists

CompletedNCT05226962

McMaster UniversityExercise, Ketosis

Start: 2022-02-15End: 2022-10-01Updated: 2022-11-07

Efficacy of Acute Intake of Ketones on Performance in Professional Road Cyclists

CompletedNCT05294939

Universidad Católica San Antonio de MurciaKetoses, Metabolic, Ketosis

Start: 2022-01-31End: 2022-03-28Updated: 2022-04-13

The Effects of Acute Ketone Monoester Supplementation on Exercise Efficiency and the Influence of Dose and Intensity

CompletedNCT05665855

McMaster UniversityExercise, Ketosis

Start: 2022-12-27End: 2023-06-30Updated: 2023-07-10

Assessment of BHB Concentration Agreement Among Sampling Locations and the Impact of Ketosis on EPO, and More

CompletedNCT06053138

Central Jutland Regional HospitalKetosis

Start: 2023-08-24End: 2024-08-30Updated: 2026-03-12

Exogenous Ketosis in a Fed and a Fasted State

RecruitingNCT06320522

University of OxfordExogenous Ketosis, Ketosis

Start: 2023-02-15End: 2024-05-31Target: 12Updated: 2024-03-20

Effects of Ketone Monoesters on Brain Function

CompletedNCT06395051

Maastricht University Medical CenterAppetite Control, Brain Insulin Sensitivity, Brain Vascular Function +2

Start: 2024-07-03End: 2024-11-15Updated: 2025-02-20

Related Papers

Effect of exogenous β-hydroxybutyrate on BDNF signaling, cognition, and amyloid precursor protein processing in humans with T2D and insulin-resistant rodents.

2025-01-132 citations

A ketone monoester drink reduces the glycemic response to an oral glucose challenge in individuals with obesity: a randomized trial.

2019-12-0168 citations