Dexmedetomidine group:Dexmedetomidine nasal spray

4 trials

Sponsors

Beijing Hospital, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, The Second Affiliated Hospital of Dalian Medical University, The First People’s Hospital of Lianyungang

Conditions

Elective patients who need knee arthroplasty and hip arthroplastyFiberoptic BronchoscopyPerioperative HemodynamicsPerioperative sleep disturbance

Phase 1

Study on sedative and analgesic effects of dexmedetomidine nasal spray and patient controlled sedation in elderly patients undergoing fiberoptic bronchoscopy

Active, not recruitingChiCTR2500111725

The Second Affiliated Hospital of Dalian Medical UniversityFiberoptic Bronchoscopy

Start: 2025-11-15Updated: 2025-11-11

Phase 4

Effect of dexmedetomidine nasal spray on perioperative sleep quality in elderly patients

Active, not recruitingChiCTR2200065202

Beijing HospitalPerioperative sleep disturbance

Start: 2022-11-01Updated: 2023-05-15

To compare the effect of preoperative intranasal dexmedetomidine on the prevention of postoperative delirium in patients undergoing knee arthroplasty and hip arthroplasty under general anesthesia: A prospective, double-blind, randomized controlled trial

Active, not recruitingChiCTR2500114488

The First People’s Hospital of LianyungangElective patients who need knee arthroplasty and hip arthroplasty

Start: 2026-01-05Updated: 2025-12-15

Unknown Phase

Efficacy of Dexmedetomidine nasal spray on Perioperative Hemodynamics in Patients with Hypertension Undergoing Major Noncardiac Surgery

Active, not recruitingChiCTR2400086576

National Cancer Center/National Clinical Research Center for Cancer/Cancer HospitalPerioperative Hemodynamics

Start: 2024-07-05Updated: 2024-07-08