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Study on sedative and analgesic effects of dexmedetomidine nasal spray and patient controlled sedation in elderly patients undergoing fiberoptic bronchoscopy

Study on sedative and analgesic effects of dexmedetomidine nasal spray and patient controlled sedation in elderly patients undergoing fiberoptic bronchoscopy

Status
Active, not recruiting
Phases
Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500111725
Enrollment
Unknown
Registered
2025-11-05
Start date
2025-11-15
Completion date
Unknown
Last updated
2025-11-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Fiberoptic Bronchoscopy

Interventions

Automatic Control Group:Self-controlled drug infusion
control group:None
Doctor Bolus Group:Doctor recommends medication injection

Sponsors

The Second Affiliated Hospital of Dalian Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
65 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1 Perform an elective painless fiberoptic bronchoscopy at the Endoscopy Center of the Second Affiliated Hospital of Dalian Medical University 2 Aged 65-80 3 ASA classification of I-III 4 Weight: 45-85 kg 5 BMI:18-28 kg/m^2

Exclusion criteria

Exclusion criteria: 1 History of abuse of sedatives and analgesics (including antiepileptic drugs) 2 Have a history of mental illness 3 Tracheal malformation 4 Pregnant and lactating women 5 Liver damage (liver enzyme elevation > 80 U/L) or renal dysfunction (serum creatinine > 2 mg/dL) 6 NYHA heart function classification of III~IV 7 Hemodynamic instability (heart rate 4 L/min at enrollment 9 Patients undergoing EBUS treatment

Design outcomes

Primary

MeasureTime frame
Completion rate check;

Secondary

MeasureTime frame
Dosage of intravenous anesthetic drugs;

Countries

China

Contacts

Public ContactLiu Jie

The Second Affiliated Hospital of Dalian Medical University

ocean107703@163.com+86 177 0987 7783

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026