Elective patients who need knee arthroplasty and hip arthroplasty
Conditions
Sponsors
The First People’s Hospital of Lianyungang
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Patients aged 50 or older undergoing elective hip or knee replacement surgery at the First People's Hospital of Lianyungang City
Exclusion criteria
Exclusion criteria: 1.Patients with a clear history of preoperative neurological and mental system diseases or those who have been using sedatives or antidepressants for a long time; 2.Has a history of alcohol abuse, drug abuse or drug dependence; 3.Has a history of brain surgery or injury; 4.Severe visual or auditory impairments; 5.Patients who failed to complete cognitive function tests or refused to participate in the study; 6.Sick sinoatrial node syndrome, second-degree or higher atrioventricular block, or other contraindications for the use of a2 adrenergic agonists; 7.Renal failure or liver dysfunction requiring dialysis.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The incidence rate of POD; | — |
Secondary
| Measure | Time frame |
|---|---|
| Adverse events;Preoperative sleep quality;Non-delirium complications;Length of hospital stay;Days of delirium;C-reactive protein, CRP; | — |
Countries
China
Contacts
Public ContactChen Yan
The First People’s Hospital of Lianyungang
Outcome results
None listed