Conventional Oxygen Therapy

DEVICE18 trials

Sponsors

Hospital Infanta Sofia, Hospital Sao Joao, University Hospital, Bordeaux, lu xiao, Second Affiliated Hospital, School of Medicine, Zhejiang University

Conditions

Acute Hypoxemic Respiratory FailureAcute Respiratory Distress SyndromeAcute Respiratory FailureBlunt Thoracic InjuryBronchoalveolar LavageBronchoscopyCOVID-19Cognitive Decline

Phase 3

High-flow Conditioned Oxygen Therapy Versus Non-invasive Ventilation: Prevention of Post-extubation Failure

CompletedNCT01191489

Hospital Infanta SofiaPost-extubation Respiratory Failure

Start: 2012-09-30End: 2014-09-30Updated: 2014-09-12

Comparative study between high flow nasal cannula versus conventional oxygen therapy on post-extubated critically ill patients

Active, not recruitingPACTR202511470786570

Al Azhar universityRespiratory Anaesthesia

Start: 2024-03-02Target: 150Updated: 2026-01-27

Unknown Phase

Palliative Use of High-flow Oxygen Nasal Cannula in End-of-life Lung Disease Patients

WithdrawnNCT02253667

Hospital Sao JoaoAcute Respiratory Distress Syndrome, Lung Disease

Start: 2014-09-30End: 2015-09-30Updated: 2017-01-25

Optiflow in Sequential Non-Invasive Ventilation

CompletedNCT02389166

University Hospital, BordeauxRespiratory Failure

Start: 2015-06-25End: 2019-03-05Updated: 2019-07-31

Evaluating High-flow Nasal Cannula Oxygen Therapy Through LUS During Weaning

lu xiaoHigh-flow Nasal Cannula Oxygen

Start: 2018-03-01End: 2019-07-01Target: 250Updated: 2018-02-13

High-flow Nasal Cannula Oxygen Therapy With the Chest Trauma Patients

Second Affiliated Hospital, School of Medicine, Zhejiang UniversityBlunt Thoracic Injury, Lung Ultrasound Score

Start: 2018-03-01End: 2019-03-30Target: 90Updated: 2018-02-12

Interest of High Flow Nasal Cannula Oxygen Therapy in Pediatric Intensive Care Unit

Hôpital d'enfants Béchir-HamzaWeaning Failure

Start: 2017-03-01End: 2019-02-28Target: 126Updated: 2018-04-23

HFNC During Bronchoscopy for Bronchoalveolar Lavage

CompletedNCT04016480

University Magna GraeciaAcute Respiratory Failure, Bronchoalveolar Lavage, Bronchoscopy

Start: 2019-09-12End: 2020-02-28Updated: 2020-12-04

The Efficacy of High-flow Nasal Cannula Oxygen Therapy in Sepsis Patients

Mackay Memorial HospitalHigh Flow Nasal Cannula, Sepsis Syndrome

Start: 2020-09-25End: 2021-09-24Target: 110Updated: 2020-09-23

High-Flow Nasal Cannula in Severe COVID-19 With Acute Hypoxemic Respiratory Failure.

CompletedNCT04609462

Fundacion Clinica Valle del LiliAcute Hypoxemic Respiratory Failure, Covid19

Start: 2020-08-11End: 2021-02-10Updated: 2021-04-01

HFNT vs. COT in COVID-19

CompletedNCT04655638

Azienda Ospedaliera Universitaria Policlinico Paolo Giaccone PalermoAcute Respiratory Failure, Covid19

Start: 2021-02-10End: 2021-10-25Updated: 2021-10-26

Effect of HFNO Therapy on Respiratory Effort After Extubation

CompletedNCT05652699

Henrik EndemanPost Extubation Acute Respiratory Failure Requiring Reintubation, Respiratory Failure

Start: 2022-10-01End: 2024-10-22Updated: 2025-01-17

High Flow Nasal Cannula in Patients Undergoing Colonoscopy

University Magna GraeciaColonoscopy

Start: 2023-02-01End: 2023-06-30Target: 36Updated: 2023-01-17

High Flow Nasal Cannula in Patients Undergoing Gastroscopy

University Magna GraeciaGastroscopy

Start: 2023-02-01End: 2023-06-30Target: 36Updated: 2023-01-20

Hyperbaric Oxygen Therapy Improves Brain Function in Patients With Cognitive Decline After COVID-19 Infection.

The First Affiliated Hospital of Zhejiang Chinese Medical UniversityCognitive Decline, COVID-19, SARS CoV 2 Infection

Start: 2023-01-29End: 2024-01-31Target: 80Updated: 2023-02-08

High Flow Nasal Oxygen at Extubation for Adults Requiring a Breathing Tube for Treating Severe Breathing Difficulties

CompletedNCT05904652

NHS Greater Glasgow and ClydeRespiratory Insufficiency

Start: 2023-09-11End: 2024-09-13Updated: 2026-04-03

Effects of Different Ventilatory Strategy During Bronchoscopy

The First Affiliated Hospital of Guangzhou Medical UniversityBronchoscopy

Start: 2023-07-20End: 2025-06-30Target: 150Updated: 2023-07-21

High-Flow Nasal Oxygen During Endoscopic Retrograde Cholangiopancreatography In Geriatric Patients

CompletedNCT07493811

Prof. Dr. Cemil Tascıoglu Education and Research Hospital OrganizationHemodynamic Instability, Hypoxemia

Start: 2025-04-15End: 2025-12-30Updated: 2026-03-25

Related Papers

High-flow nasal therapy vs conventional oxygen therapy in mild COVID-19 hypoxaemia: a Bayesian reanalysis of the COVID-HIGH Trial

Journal of Anesthesia Analgesia and Critical Care2026-02-21

Physiological Effects of High-Flow Nasal Oxygen Compared With Conventional Oxygen Therapy: A Randomized Trial in Postextubation Patients.

2025-12-15

High-flow nasal oxygen versus conventional oxygen therapy in patients with COVID-19 pneumonia and mild hypoxaemia: a randomised controlled trial

Thorax2022-05-1777 citations

Effect of High-Flow Oxygen Therapy vs Conventional Oxygen Therapy on Invasive Mechanical Ventilation and Clinical Recovery in Patients With Severe COVID-19

JAMA2021-12-07286 citations

High-flow nasal cannula oxygen therapy for outpatients undergoing flexible bronchoscopy: a randomised controlled trial

Thorax2021-04-2966 citations

Effect of Postextubation High-Flow Nasal Cannula vs Noninvasive Ventilation on Reintubation and Postextubation Respiratory Failure in High-Risk Patients

JAMA2016-10-05587 citations

Effect of Postextubation High-Flow Nasal Cannula vs Conventional Oxygen Therapy on Reintubation in Low-Risk Patients

JAMA2016-03-15528 citations