Bronchoscopy
Conditions
Brief summary
The execution of diagnostic-therapeutic investigations by bronchial endoscopy can expose the patient to hypoxemia. For this reason, oxygen therapy is administered at low or high flows during the course of bronchoscopic procedures. Our study aim was to evaluate the efficacy and complications of High-flow nasal oxygen (HFNO) via Supraglottic jet oxygenation and ventilation (SJOV)during flexible bronchoscopy.
Interventions
Conventional Oxygen Therapy will be administered through Nasal catheter
DEVICEHigh-flow nasal oxygen
High Flow Nasal Cannula will be administered
Nasal jet tube will be administered
Sponsors
The First Affiliated Hospital of Guangzhou Medical University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to 85 Years
Healthy volunteers
No
Inclusion criteria
* need for bronchial endoscopy
Exclusion criteria
* life-threatening cardiac aritmia or acute miocardical infarction within 6 weeks need for invasive or non invasive ventilation presence of pneumothorax or pulmonary enphisema or bullae recent (within 1 week) thoracic surgery presence of chest burns presence of tracheostomy pregnancy nasal or nasopharyngeal diseases dementia lack of consent or its withdrawal
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Compare the intraoperative oxygenation. | During bronchoscopy, an average of 0.5 hour. | The study will monitor the SpO2， heart rate(HR) and mean arterial pressure (MAP) during the procedure. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Arterial blood gases | At end of of bronchoscopy,an average of 0.5 hour after bronchoscope insertion. | Arterial blood gas analysis will be monitored at end of of procedure. |
| Assess the regional ventilation distribution by Electrical impedance tomography . | During bronchoscopy, an average of 0.5 hour. | Measurements will be done after bronchoscope insertion and at the end of the procedure. |
Contacts
Primary ContactLiya Lu
Outcome results
None listed