Comparative study between high flow nasal cannula versus conventional oxygen therapy on post-extubated critically ill patients

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

PACTR

Registry ID

PACTR202511470786570

Enrollment

150

Registered

2025-11-20

Start date

2024-03-02

Completion date

Unknown

Last updated

2026-01-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Respiratory Anaesthesia

Interventions

Conventional oxygen therapy

high flow nasal cannula

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients who underwent planned extubation after at least 24 hours of invasive mechanical ventilation Patients who passed the Spontaneous Breathing Trial (SBT) Patients who were free of lung surgery

Exclusion criteria

Exclusion criteria: Patients under the age of 21years old. Patients with urgent tracheal intubation, such as respiratory and cardiac arrest, require immediate after-extubation care. Patients with multiple organ failure, tissue damage, and other diseases that seriously endangered their lives. Patients with preoperative respiratory diseases and failed SBT. Patients with contraindications to HFNC or non-invasive positive pressure ventilation. Patients with impaired consciousness, hemodynamic instability (mean arterial pressure < 60 mmHg), or exacerbations.

Design outcomes

Primary

Measure	Time frame
Incidence rate of reintubation within 72 hours post-extubation.	—

Secondary

Measure	Time frame
Respiratory parameters: post extubation oxygenation indices as (SpO2, respiratory rate, PaO2/FiO2 ratio)	—

Countries

Egypt

Contacts

Public ContactHayam Shaaban Shaaban

Lecturer in Anesthesiology Intensive care and pain management Faculty of medicine Al Azhar University

Shaaban_hyam@gmail.com00201555769843

Outcome results

None listed

Source: PACTR (via WHO ICTRP) · Data processed: Feb 4, 2026