High Flow Oxygen Therapy, ENDOBRONCHIAL ULTRASOUND - TRANSBRONCHIAL NEEDLE ASPIRATION, Sedation, Sedation Complication, Blood Gas Analysis
Conditions
Keywords
High flow oxygen therapy,, Endobronchial Ultrasound-Transbronchial Needle Aspiration(EBUS-TBNA), Sedation, Sedation Complications, Blood Gas Analysis
Brief summary
This study aims to evaluate the effects of high-flow nasal oxygen therapy on respiratory complications, blood gas parameters, and post-procedural recovery in patients undergoing sedated endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA). Participants will be assigned to receive either high-flow nasal oxygen therapy or conventional oxygen therapy during the procedure. The incidence of respiratory complications, blood gas changes, and recovery outcomes will be compared between the two groups.
Interventions
High-flow nasal oxygen therapy administered during sedated EBUS-TBNA procedures to provide enhanced oxygenation and respiratory support.
Conventional oxygen therapy administered during sedated EBUS-TBNA procedures using standard oxygen delivery methods
Sponsors
Dr Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital
Study design
Observational model
CASE_CONTROL
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
Age ≥18 years. Scheduled to undergo sedated EBUS-TBNA. Ability to provide written informed consent. ASA physical status I-III.
Exclusion criteria
* Age \<18 years. * Pregnancy. * Requirement for endotracheal intubation or general anesthesia. * Severe hemodynamic instability. * Refusal to participate in the study. * Contraindication to high-flow nasal oxygen therapy.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Respiratory Complications | During the procedure | Incidence of respiratory complications during sedated EBUS-TBNA, including hypoxemia, oxygen desaturation, apnea, airway obstruction, and the need for airway interventions. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Oxygen partial pressure (PaO2) | Baseline and within 15 minutes after completion of the endobronchial Ultrasound-Transbronchial Needle Aspiration (EBUS-TBNA) procedure | Changes in venous oxygen partial pressure(PaO2) measured at baseline and after sedated EBUS-TBNA |
| Carbon dioxide partial pressure (PvCO2) | Baseline and within 15 minutes after completion of the EBUS-TBNA | Changes in venous carbon dioxide partial pressure (PvCO2) measured at baseline and within 15 minutes after completion of sedated EBUS-TBNA. |
| Venous pH | Baseline and within 15 minutes after completion of the EBUS-TBNA procedure. | Changes in venous pH measured at baseline and within 15 minutes after completion of sedated EBUS-TBNA |
| Venous Oxygen Saturation (SvO2) | Baseline and within 15 minutes after completion of the EBUS-TBNA procedure. | Changes in venous oxygen saturation (SvO2) measured at baseline and within 15 minutes after completion of sedated EBUS-TBNA. |
| Recovry Time | Up to 2 hours post-procedure | Time from completion of sedated EBUS-TBNA until achievement of a Modified ALdrete Recovery Score ≥9. |
Countries
Turkey (Türkiye)
Contacts
CONTACTÖZLEM KAPUSUZ KÖRDUMAN, MD
CONTACTGüldeniz Argun, Prof
Outcome results
None listed