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High-flow Nasal Cannula Oxygen Therapy With the Chest Trauma Patients

High-flow Nasal Cannula Oxygen Therapy With the Chest Trauma Patients

Status
UNKNOWN
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT03430258
Enrollment
90
Registered
2018-02-12
Start date
2018-03-01
Completion date
2019-03-30
Last updated
2018-02-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Blunt Thoracic Injury, Lung Ultrasound Score

Brief summary

This prospective randomized controlled study was conducted in the emergency intensive care units (EICU) of the second affiliated hospital Zhejiang university school of medicine, a large tertiary university hospital in HangZhou, China.The aim of this randomized study was to compare the effectiveness of high-flow nasal cannula with conventional oxygen therapy in ICU patients with blunt thoracic injury.

Detailed description

This prospective randomized controlled study was conducted in the emergency intensive care units (EICU) of the second affiliated hospital Zhejiang university school of medicine, a large tertiary university hospital in HangZhou, China.The aim of this randomized study was to compare the effectiveness of high-flow nasal cannula with conventional oxygen therapy in ICU patients with blunt thoracic injury.

Interventions

DEVICEhigh-flow nasal cannula

high flow of air with supplemental oxygen was delivered by an Optiflow cannula interface using an AIRVO 2 blower humidifier

DEVICEConventional oxygen therapy

Conventional oxygen therapy

Sponsors

Second Affiliated Hospital, School of Medicine, Zhejiang University
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

\- The trauma registry was used to identify patients with moderate to severe blunt thoracic injury (abbreviated injury scale (AIS) chest score ≥3) admitted to the ICU

Exclusion criteria

1. had intubation and used the mechanical ventilation within 2 hours 2. had the emergency surgerys within 2 hours 3. patients can not accessed by transthoracic lung ultrasound because of the sever aerodermectasia or pneumothorax 4. the Glasgow Coma Scale \<8

Design outcomes

Primary

MeasureTime frameDescription
compare the effectiveness of high-flow nasal cannula with conventional oxygen therapy in ICU patients with blunt thoracic injury.72 hoursHigh-flow nasal cannula could reduce the intube rate of patients with blunt thoracic injury,and improve the the lung aeration for patients with thoracic injury

Secondary

MeasureTime frameDescription
number of days in ICU7 daysHigh-flow nasal cannula could reduce the number of days for the patients treatments in ICU

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026