Vitamin K2

DIETARY_SUPPLEMENT15 trials

Sponsors

Tokai University, Maastricht University Medical Center, Danisco, Onze Lieve Vrouw Hospital, Ain Shams University

Conditions

Aortic Valve CalcificationAortic Valve StenosisBicuspid Aortic ValveCachexiaCarboxylation LevelCardiometabolic Risk FactorsDiabete Type 2End Stage Renal Disease

Phase 1

Inhibition of coronary calcification by vitamin K2

Active, not recruitingJPRN-UMIN000002760

Tokai Universitycoronary calcification

Start: 2008-11-01Target: 30Updated: 2025-07-18

Phase 2

Vitamin K2 Intervention in Patients With Vitamin K Antagonists

CompletedNCT01533441

DaniscoThrombosis

Start: 2012-02-29End: 2013-04-30Updated: 2014-04-08

Bicuspid Aortic Valve Stenosis and the Effect of vItamin K2 on Calciummetabolism on 18F-NaF PET/MRI

Maastricht University Medical CenterAortic Valve Stenosis, Bicuspid Aortic Valve

Start: 2016-08-31End: 2019-12-31Target: 44Updated: 2018-03-22

Effect of Vitamin K 2 on Vascular Calcification in Hemodialysis Patients

Ain Shams UniversityEnd Stage Renal Disease

Start: 2019-09-01End: 2020-02-01Target: 60Updated: 2019-10-30

Comparative Study Evaluating the Effect of Vitamin K1 Versus Vitamin K2 on Vascular Calcification in Dialysis Patients

CompletedNCT04477811

Ain Shams UniversityEnd Stage Renal Disease on Dialysis

Start: 2020-07-25End: 2021-01-01Updated: 2021-07-21

Phase 4

Effect on Vascular Calcification of Replacing Warfarin by Rivaroxaban With or Without VitK2 in Hemodialysis Patients

CompletedNCT02610933

Onze Lieve Vrouw HospitalVascular Calcification

Start: 2015-11-30End: 2019-01-23Updated: 2019-01-28

Unknown Phase

Comparison of Efficacy of Different Dosages Vitamin K2

CompletedNCT01194778

Maastricht University Medical CenterCarboxylation Level, Vitamin K-dependent Proteins

Start: 2009-10-31End: 2010-08-31Updated: 2010-09-03

SLOW-Slower Progress of caLcificatiOn With Vitamin K2

National and Kapodistrian University of AthensAortic Valve Calcification, Aortic Valve Stenosis, Mitral Annular Calcification +2

Start: 2019-09-23End: 2023-12-23Target: 200Updated: 2021-09-01

viTAmin K2 and rEcOVery From ExeRcise

CompletedNCT04676958

University of GlasgowExercise, Inflammation, Oxidative Stress +3

Start: 2021-04-01End: 2023-07-01Updated: 2023-11-28

Vitamin K2 Supplements for Muscle Recovery

Lithuanian Sports UniversityCachexia, Muscle Atrophy

Start: 2021-12-15End: 2023-12-31Target: 60Updated: 2021-12-17

Vitamin K2 and Muscle Weakness in Type 2 Diabetes

Dasman Diabetes InstituteDiabete Type 2

Start: 2022-03-21End: 2024-10-31Target: 150Updated: 2023-07-28

Effect of Vitamin K2 in the Treatment of Nocturnal Leg Cramps in Older Population

CompletedNCT05547750

The Third People's Hospital of ChengduNocturnal Leg Cramps

Start: 2022-10-01End: 2023-12-31Updated: 2025-01-17

Antioxidant and Immune Effects of Vitamin K2

CompletedNCT05675163

NIZO Food ResearchInflammation, Oxidative Stress

Start: 2022-11-15End: 2023-05-16Updated: 2023-06-18

Effect of Vitamin K2 Over Osteocalcin, Leptin, Cytokines, and Cardiovascular Risk in Young Adults With Overweight and Obesity

CompletedNCT05995522

University of GuadalajaraCardiometabolic Risk Factors, Overweight and Obesity

Start: 2023-09-01End: 2023-12-31Updated: 2024-05-08

Ischemic Stroke Nutrition Intervention Study

Active, not recruitingNCT06817512

Harbin Medical UniversityIschemic Stroke

Start: 2025-03-23End: 2028-01-31Updated: 2026-03-03

Related Papers

The effects of vitamin K2 on recovery from muscle damaging resistance exercise in young and older adults – The TAKEOVER randomised controlled trial

Enlighten: Publications (The University of Glasgow)2025-11-25

Vitamin K<sub>2</sub> in Managing Nocturnal Leg Cramps

JAMA Internal Medicine2024-10-2811 citations

Effect of vitamin K2 in the treatment of nocturnal leg cramps in the older population: Study protocol of a randomized, double-blind, controlled trial

Frontiers in Nutrition2023-02-231 citations

Protocol for a randomised controlled trial to investigate the effects of vitamin K2 on recovery from muscle-damaging resistance exercise in young and older adults-the TAKEOVER study.

2022-12-204 citations

The impact of vitamin K2 and native vitamin D supplementation on vascular calcification in pediatric patients on regular hemodialysis. A randomized controlled trial.

2021-11-298 citations