Inhibition of coronary calcification by vitamin K2

Inhibition of coronary calcification by vitamin K2 - K2-SUMMIT 2

Status

Active, not recruiting

Phases

Phase 1

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000002760

Enrollment

Registered

2009-11-19

Start date

2008-11-01

Completion date

Unknown

Last updated

2025-07-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

coronary calcification

Interventions

vitamin K2

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria:

Exclusion criteria

Exclusion criteria: 1. under treatment of osteoporosis 2. steroid hormone treatment 3. warfarin 4. esophageal stenosis 5. allergy against vitamin K2 6. pregnant women 7. no coronary calcification or calcification score > 10,000

Design outcomes

Primary

Measure	Time frame
Reduction of coronary calcification	—

Secondary

Measure	Time frame
Serum level of bone relating proteins such as ucOC, MGP, OPG. ABI, pWV. Density of bone.	—

Countries

Japan

Contacts

Public ContactSachiko Yajima

Tokai University Cardiology

s.yajima@tokai-u.jp0463-93-1121

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Feb 4, 2026