Tryptophan

OTHER13 trials

Sponsors

National Institute on Drug Abuse (NIDA), Queen's University, The Hospital for Sick Children, University of Groningen, University of Maryland, Baltimore

Conditions

Alzheimer's DiseaseCocaine-Related DisordersElite Adolescent AthletesHealthyHealthy AgingObese AdolescentObesityProtein Absorption and Amino Acid Availability

Early Phase 1

Serotonin and Everyday Social Interaction

CompletedNCT02051569

University of GroningenSocial Behaviour

Start: 2012-08-31End: 2014-01-31Updated: 2014-01-31

Phase 1

The Effects of Kynurenine Aminotransferase Inhibition in People With Schizophrenia

CompletedNCT04013555

University of Maryland, BaltimoreSchizoaffective Disorder, Schizophrenia, Schizophreniform Disorder

Start: 2020-01-20End: 2024-08-14Updated: 2026-02-11

Phase 2

Tryptophan and Behavior Therapy for Cocaine Abuse - 1

CompletedNCT00000324

National Institute on Drug Abuse (NIDA)Cocaine-Related Disorders

Start: 1997-03-31End: 2001-04-30Target: 200Updated: 2017-01-12

Tryptophan MRI in People With Schizophrenia and Healthy Controls

CompletedNCT02067975

University of Maryland, BaltimoreSchizophrenia

Start: 2014-08-14End: 2019-12-31Updated: 2024-07-30

A Phase II, Randomized, Double-blind, Placebo-controlled, in Parallel Groups Clinical Trial to Assess the Safety and Efficacy of Dietary Supplementation With Tryptophan to Achieve Weight Loss, and Its Neuropsychological Effects in Adolescents With Obesity

CompletedNCT02612259

Fundació Sant Joan de DéuObesity

Start: 2012-01-31End: 2014-06-30Updated: 2015-11-23

Phase 4

Double Blind Study of Trp01 in Patients With Alzheimer's Disease

CompletedNCT00202124

Queen's UniversityAlzheimer's Disease

Start: 2001-04-30End: 2002-03-31Target: 12Updated: 2005-09-20

Unknown Phase

Tryptophan Requirement of Healthy School Age Children

CompletedNCT02018588

The Hospital for Sick ChildrenHealthy

Start: 2013-12-31End: 2017-12-31Updated: 2018-02-09

Metabolic Availability of Tryptophan From White Maize

CompletedNCT02402179

The Hospital for Sick ChildrenHealthy

Start: 2015-03-31End: 2016-05-31Updated: 2016-11-15

Nutrients to Enhance Sleep Quality and Quantity

CompletedNCT03288077

PepsiCo Global R&DSleepiness in Athletes

Start: 2015-06-30End: 2018-08-31Updated: 2018-09-14

Effect of the Quality of Dietary Proteins on the Sleep Young Elite Athletes and the Obese Adolescent

University Hospital, Clermont-FerrandElite Adolescent Athletes, Obese Adolescent

Start: 2019-11-04End: 2022-03-01Target: 48Updated: 2019-11-14

Anaesthesia and Tryptophan Pathway

Assiut UniversityTryptophan Pathway

Start: 2020-07-08End: 2020-08-10Target: 48Updated: 2020-07-16

The Tryptophan Requirement in Healthy Adults

RecruitingNCT06283706

The Hospital for Sick ChildrenHealthy Aging

Start: 2024-06-01End: 2025-12-01Target: 40Updated: 2025-05-30

MA of Tryptophan in Cornmeal in Healthy Adults>60y

Enrolling by invitationNCT07272668

The Hospital for Sick ChildrenProtein Absorption and Amino Acid Availability

Start: 2025-11-29End: 2026-05-02Target: 40Updated: 2025-12-09

Related Papers

Dietary Tryptophan Requirements in Adults Aged Over 60 Years is not Affected by Sex or Decades of Age.

2026-09-11

Tryptophan challenge in individuals with schizophrenia and healthy controls: acute effects on circulating kynurenine and kynurenic acid, cognition and cerebral blood flow.

2023-04-2814 citations

Tryptophan Requirement in School-Age Children Determined by the Indicator Amino Acid Oxidation Method is Similar to Current Recommendations.

2019-02-017 citations

Metabolic Availability of the Limiting Amino Acids Lysine and Tryptophan in Cooked White African Cornmeal Assessed in Healthy Young Men Using the Indicator Amino Acid Oxidation Technique.

2018-06-0119 citations