Proton Radiation Therapy

RADIATION13 trials

Sponsors

Sakurai Hideyuki, M.D. Anderson Cancer Center, Loma Linda University, Massachusetts General Hospital, Abramson Cancer Center at Penn Medicine

Conditions

Adenoid Cystic CarcinomaCervical CancerCholangiocarcinomaEarly-Stage Breast CancerEsophagogastric CancerEsthesioneuroblastomaGastroesophageal Junction AdenocarcinomaHepatocellular Carcinoma

Phase 1

Proton Therapy and Bevacizumab for Primary Liver Tumors

TerminatedNCT00426829

M.D. Anderson Cancer CenterCholangiocarcinoma, Hepatocellular Carcinoma, Liver Cancer

Start: 2007-05-31End: 2009-11-30Updated: 2012-08-01

Proton Beam Therapy for Treatment of Hepatocellular Carcinoma

CompletedNCT00614913

Loma Linda UniversityHepatocellular Carcinoma, Liver Cancer

Start: 1998-05-31End: 2009-02-28Updated: 2012-08-20

Chemotherapy and Proton Radiation for the Treatment of Locally Advanced Lung Cancer

TerminatedNCT00614484

Loma Linda UniversityLocally Advanced Non-Small Cell Lung Cancer

Start: 1999-08-31End: 2011-06-30Updated: 2014-05-22

Phase 2

PRT for skull base chordoma and chondrosarcoma.

RecruitingJPRN-jRCT1032180086

Sakurai HideyukiSkull base chordoma or chondrosarcoma proton radiation therapy, proton beam therapy, chordoma, chondrosarcoma, radiotherapy

Start: 2019-03-22Target: 60Updated: 2026-06-29

Folfox+Irinotecan+Chemort In Esophageal Cancer

RecruitingNCT04656041

Massachusetts General HospitalEsophagogastric Cancer, Gastroesophageal Junction Adenocarcinoma

Start: 2021-06-29End: 2027-12-31Target: 40Updated: 2025-11-14

Unknown Phase

Proton Therapy for Early Stage Breast Cancer

CompletedNCT00614172

Loma Linda UniversityEarly-Stage Breast Cancer

Start: 2004-02-29End: 2020-05-12Updated: 2023-09-21

Late Effects of Proton Radiation Therapy in Patients With Low-Grade Glioma

CompletedNCT00681473

Massachusetts General HospitalLow Grade Gliomas

Start: 2007-07-31End: 2015-08-31Updated: 2017-03-07

Proton Radiotherapy for Stage I, IIA, and IIB Seminoma

CompletedNCT01557790

Abramson Cancer Center at Penn MedicineStage I, IIA and IIB Seminoma

Start: 2012-03-31End: 2017-12-31Updated: 2020-04-13

Intensity-Modulated or Proton Radiation Therapy for Sinonasal Malignancy

Massachusetts General HospitalAdenoid Cystic Carcinoma, Esthesioneuroblastoma, Melanoma +6

Start: 2011-07-12End: 2025-11-30Updated: 2023-09-21

Proton Beam Teletherapy for Post-Hysterectomy Cancers of the Uterus and Cervix

CompletedNCT01600040

Massachusetts General HospitalCervical Cancer, Uterine Cancer

Start: 2013-08-31End: 2023-08-10Updated: 2024-10-29

Study on the Safety and Effectiveness of Varian ProBeam Proton Therapy Equipment in the Treatment of Solid Tumors

CompletedNCT05914142

Guangzhou Concord Cancer CenterProton Therapy, Radiation Therapy, Solid Tumor

Start: 2022-12-15End: 2023-07-04Updated: 2023-11-07

Varian ProBeam360° Proton Therapy System China Clinical Trial (Wuhan)

CompletedNCT06347731

Varian, a Siemens Healthineers CompanyTumor, Solid

Start: 2024-09-05End: 2025-04-04Updated: 2025-12-15

Proton Therapy for Recurrent Nasopharyngeal Carcinoma

RecruitingNCT07412314

Guangzhou Concord Cancer CenterRecurrent Nasopharyngeal Carcinoma

Start: 2025-03-10End: 2028-03-10Target: 52Updated: 2026-03-09

Related Papers

Phase II study of neoadjuvant NALIRIFOX followed by chemoradiation with paclitaxel and carboplatin in locally advanced gastroesophageal cancer.

Journal of Clinical Oncology2025-01-27