PRT for skull base chordoma and chondrosarcoma.

Phase II trial of Proton Radiation Therapy for skull base chordoma and chondrosarcoma. - PRT for skull base chordoma and chondrosarcoma. (Pro-Chordo Study)

Status

Recruiting

Phases

Phase 2

Study type

Interventional

Source

JPRN

Registry ID

JPRN-jRCT1032180086

Enrollment

Registered

2019-01-17

Start date

2019-03-22

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Skull base chordoma or chondrosarcoma proton radiation therapy, proton beam therapy, chordoma, chondrosarcoma, radiotherapy

Interventions

Proton Radiation Therapy

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1, Pathological diagnosis is chordoma or chondrosarcoma 2, General condition is maintained (PS 0-2 or PS 3 caused by tumor) 3, When tumor is controlled,5-year survival is expected. 4, Obtain written informed consent. 5, 15 years old or more.

Exclusion criteria

Exclusion criteria: 1, Multiple primary cancers 2, Invasion for brain stem or optic chiasm 3, Distant metastases 4, Active infectious meningitis 5, Pregnant, unwilling to practice contraception during study, or lactating female. 6, Not suitable for participation by mental illnesses 7, Difficult to participate by the judgment of a doctor

Design outcomes

Primary

Measure	Time frame
3 year local recurrence free survival	—

Secondary

Measure	Time frame
5 or 10 year local recurrence free survival, Late toxicity	—

Contacts

Public ContactMasashi Mizumoto

University of Tsukuba Hospital

mizumoto@pmrc.tsukuba.ac.jp+81-29-853-7100

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026