Propafenone

DRUG18 trials

Sponsors

Region Oerebro Laen, Helsinki University Central Hospital, Národny ustav srdcovych a cievnych chorob a.s., University Of Pecs, Gottsegen National Cardiovascular Center, Assistance Publique Hopitaux De Paris, Olpha AS, University of Washington, National Heart, Lung, and Blood Institute (NHLBI)

Conditions

ArrhythmiaArrhythmia, CardiacAsymptomatic Patients with frequent PVCs and normal LVEFAtrial FibrillationAtrial Fibrillation (AF)Atrial fibrillationBioequivalenceCardiovascular Diseases

Phase 1

Bioequivalence of RYTHMOL SR® Manufactured at Two Different Sites

CompletedNCT01956487

GlaxoSmithKlineArrhythmia, Cardiac

Start: 2012-04-11End: 2012-06-27Updated: 2017-06-12

Bioequivalence Study of Two Formulations of Propafenone 300 mg Film-coated Tablets in Healthy Adult Volunteers After a Single Oral Dose Administration Under Fasting Conditions

CompletedNCT03915340

Pharmtechnology LLCBioequivalence

Start: 2019-03-23End: 2019-05-08Updated: 2019-06-06

Phase 3

Atrial Fibrillation Follow-up Investigation of Rhythm Management (AFFIRM)

CompletedNCT00000556

National Heart, Lung, and Blood Institute (NHLBI)Arrhythmia, Atrial Fibrillation, Cardiovascular Diseases +1

Start: 1995-03-31End: 2002-09-30Updated: 2016-03-25

Cardiac Arrest in Seattle: Conventional Versus Amiodarone Drug Evaluation (CASCADE)

CompletedNCT00000464

University of WashingtonArrhythmia, Cardiovascular Diseases, Heart Arrest +3

Start: 1987-04-30Updated: 2013-07-29

High Intensity Focused Ultrasound (HIFU) Ablation System Study

SuspendedNCT00392106

ProRhythm, Inc.Atrial Fibrillation

Start: 2006-04-30End: 2011-06-30Target: 240Updated: 2008-06-17

First-line cryoablation for early treatment of Persistent Atrial Fibrillation – a randomized study comparing early trigger isolation using the Cryoballoon versus antiarrhythmic medication

RecruitingCTIS2023-505962-28-00

Region Oerebro Laen, Helsinki University Central Hospital, Národny ustav srdcovych a cievnych chorob a.s., University Of Pecs, Gottsegen National Cardiovascular CenterPersistent symptomatic atrial fibrillation

Start: 2024-05-08Target: 256Updated: 2025-09-29

SUPPRESS. Prophylactic frequent premature ventricular complexeS sUPPression on left ventriculaR function impairmEnt in aSymptomatic patientS

RecruitingCTIS2024-516372-14-00

Assistance Publique Hopitaux De ParisAsymptomatic Patients with frequent PVCs and normal LVEF

Start: 2025-01-13Target: 298Updated: 2024-09-18

Phase 4

Antiarrhythmic Drugs Assessment in Preventing Atrial Fibrillation

Xinhua Hospital, Shanghai Jiao Tong University School of MedicineAtrial Fibrillation

Start: 2014-05-31End: 2017-05-31Target: 600Updated: 2014-05-23

Efficacy and Safety of Sotalol in Children With Arrhythmia

Shengjing HospitalArrhythmia

Start: 2019-08-31End: 2022-12-31Target: 500Updated: 2019-03-29

Antazoline in Comparison to Propafenone in Pharmacological Cardioversion of Atrial Fibrillation.

Centre of Postgraduate Medical EducationAtrial Fibrillation

Start: 2019-09-01End: 2026-01-01Target: 105Updated: 2023-02-14

An open-label, randomized clinical trial comparing Etacizin versus Propafenone in Atrial Fibrillation

Not yet recruitingCTIS2025-521267-13-01

Olpha ASAtrial fibrillation

Target: 30Updated: 2025-09-11

Dronedarone Rhythm Intervention for Early Atrial Fibrillation

Not yet recruitingNCT07270848

Inha University HospitalAtrial Fibrillation (AF)

Start: 2026-01-01End: 2028-12-31Target: 1898Updated: 2025-12-22

Unknown Phase

Efficacy and Safety of Electrical Versus Pharmacological Cardioversion in Early Atrial Fibrillation

CompletedNCT00933634

Valduce HospitalAtrial Fibrillation

Start: 2006-01-31End: 2008-11-30Target: 247Updated: 2009-07-07

Efficacy of Propafenone Versus Dronedarone for the Maintenance of Sinus Rhythm in Patients With Atrial Fibrillation

CompletedNCT01991119

Samsung Medical CenterAtrial Fibrillation

Start: 2011-05-31End: 2013-10-31Updated: 2013-11-25

Catheter Ablation Compared With Pharmacological Therapy for Atrial Fibrillation (CAPTAF Trial)

Uppsala University HospitalAtrial Fibrillation, Quality of Life

Start: 2008-05-31End: 2018-09-30Updated: 2017-05-09

Comparison of Brain Perfusion in Rhythm Control and Rate Control of Persistent Atrial Fibrillation

Yonsei UniversityPersistent Atrial Fibrillation

Start: 2015-11-30End: 2020-11-30Target: 200Updated: 2019-01-28

Beta-blocker vs. Ic Antiarrhythmic Drug for PVC

WithdrawnNCT03561935

Yong Seog OhPremature Ventricular Complex

Start: 2015-06-30End: 2019-11-01Updated: 2024-04-23

Propafenone in the Treatment of Atrial Fibrillation

CompletedNCT03674658

TSH Biopharm Corporation LimitedAtrial Fibrillation

Start: 2019-07-11End: 2021-08-17Updated: 2021-09-23

Related Papers

An open-label randomized noninferior study of generic name and brand name of propafenone for rhythm control in patients with paroxysmal atrial fibrillation

Journal of the Chinese Medical Association2023-02-17

Systolic Blood Pressure Visit-to-Visit Variability and Major Adverse Outcomes in Atrial Fibrillation

Hypertension2017-10-0431 citations

Efficacy of dronedarone versus propafenone in the maintenance of sinus rhythm in patients with atrial fibrillation after electrical cardioversion.

2014-08-1611 citations

Cardioversion of acute atrial fibrillation in the emergency department: a prospective randomised trial.

2011-03-2130 citations