Nitroprusside

DRUG11 trials

Conditions

AgingBlood FlowCVA (Cerebrovascular Accident)CancerCerebral HemorrhageCerebral OxygenationDepressionEndothelial Dysfunction

Early Phase 1

Early Neurovascular Adaptations in Aging Women

RecruitingNCT06520982

University of Missouri-ColumbiaAging, Blood Flow, Sympathetic Nervous System +1

Start: 2024-09-20End: 2028-06-30Target: 64Updated: 2025-11-26

Phase 2

Dose-response Study of Sodium Nitroprusside in Children Requiring Controlled Hypotension in the Operating Room

CompletedNCT00135668

The Emmes Company, LLCHypotension

Start: 2005-08-31End: 2009-02-28Updated: 2024-01-02

Effect of Strategy for Blood Pressure Control on Cerebral Oxygen Balance During Aortic Coarctation Repair: A Randomized Study

CompletedNCT00535808

University Hospital, GhentCerebral Oxygenation

Start: 2007-10-31End: 2011-03-31Updated: 2012-07-13

THE REOPEN-AMI STUDY - Intracoronary Nitroprusside Versus Adenosine in Acute Myocardial Infarction

CompletedNCT00590070

Catholic University of the Sacred HeartMyocardial Infarction

Start: 2008-01-31End: 2011-09-30Updated: 2012-03-27

Sodium Nitroprusside for Blood Pressure Reduction in the ICU (SNP2)

CompletedNCT00621816

Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)Hypertension

Start: 2009-01-31End: 2011-01-31Updated: 2011-12-06

Ketamine and Nitroprusside for Depression

CompletedNCT03102736

Icahn School of Medicine at Mount SinaiDepression

Start: 2017-02-14End: 2019-06-12Updated: 2020-07-02

Phase 4

Nitroprusside for Prevention of no-Reflow in Primary Angioplasty

TerminatedNCT00128791

Soroka University Medical CenterMyocardial Infarction

Start: 2003-01-31End: 2005-04-30Target: 100Updated: 2007-05-25

Unknown Phase

Intensive Blood Pressure Reduction in Acute Cerebral Haemorrhage

CompletedNCT00226096

The George InstituteCerebral Hemorrhage, CVA (Cerebrovascular Accident), Intracranial Hemorrhages

Start: 2005-11-30End: 2007-09-30Updated: 2008-06-26

Bevacizumab and Endothelium Dependent Vasodilation

CompletedNCT01125943

Radboud University Medical CenterCancer, Endothelial Dysfunction, Hypertension

Start: 2010-06-30End: 2011-11-30Updated: 2013-01-10

Remifentanil and Nitroprusside for Controlled Hypotension

CompletedNCT02001298

Jeju National University School of MedicineHypotension, Controlled

Start: 2012-06-30Updated: 2013-12-04

Vascular Function and Uterine Fibroids

CompletedNCT02123069

Mayo ClinicLeiomyoma

Start: 2013-04-30End: 2018-03-01Updated: 2018-03-02

2026-03-19

Effects of blood pressure lowering in relation to time in acute intracerebral haemorrhage: a pooled analysis of the four INTERACT trials.

2025-07-019 citations

Optimum Baseline Clinical Severity Scale Cut Points for Prognosticating Intracerebral Hemorrhage: INTERACT Studies

Stroke2023-11-2918 citations

Sudden onset severe epigastric pain in a man aged 48 years

Emergency Medicine Journal2022-09-201 citations

Role of nitric oxide signaling in the antidepressant mechanism of action of ketamine: A randomized controlled trial

Journal of Psychopharmacology2021-02-014 citations

Sex differences in treatment, radiological features and outcome after intracerebral haemorrhage: Pooled analysis of Intensive Blood Pressure Reduction in Acute Cerebral Haemorrhage trials 1 and 2

European Stroke Journal2020-09-2127 citations

Utility-Weighted Modified Rankin Scale Scores for the Assessment of Stroke Outcome

Stroke2020-07-0935 citations

Infratentorial Intracerebral Hemorrhage

Stroke2019-03-2033 citations

Determinants of the high admission blood pressure in mild-to-moderate acute intracerebral hemorrhage

Journal of Hypertension2019-02-068 citations

Associations with health-related quality of life after intracerebral haemorrhage: pooled analysis of INTERACT studies

Journal of Neurology Neurosurgery & Psychiatry2016-10-2124 citations

Early blood pressure lowering in patients with intracerebral haemorrhage and prior use of antithrombotic agents: pooled analysis of the INTERACT studies

Journal of Neurology Neurosurgery & Psychiatry2016-05-1330 citations

Admission Heart Rate Predicts Poor Outcomes in Acute Intracerebral Hemorrhage

Stroke2016-05-1133 citations

Prognostic significance of delayed intraventricular haemorrhage in the INTERACT studies

Journal of Neurology Neurosurgery & Psychiatry2016-01-0824 citations

Evaluation of sodium nitroprusside for controlled hypotension in children during surgery

Frontiers in Pharmacology2015-07-0616 citations

Rapid Blood Pressure Lowering According to Recovery at Different Time Intervals after Acute Intracerebral Hemorrhage: Pooled Analysis of the INTERACT Studies.

2015-03-2521 citations

Prognostic Significance of Perihematomal Edema in Acute Intracerebral Hemorrhage

Stroke2015-02-26150 citations

No Relationship of Lipid-Lowering Agents to Hematoma Growth

Stroke2015-02-069 citations

Higher mortality in patients with right hemispheric intracerebral haemorrhage: INTERACT1 and 2

Journal of Neurology Neurosurgery & Psychiatry2015-01-1418 citations

Clinical Prediction Algorithm (BRAIN) to Determine Risk of Hematoma Growth in Acute Intracerebral Hemorrhage

Stroke2014-12-12120 citations

Sodium nitroprusside is not associated with metabolic acidosis during intraoperative infusion in children.

2013-04-303 citations

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