Hypotension, Controlled
Conditions
Keywords
remifentanil, nitroprusside, hypotension
Brief summary
The purpose of this study is the comparison of the cardiovascular effects of remifentanil and nitroprusside for controlled hypotension
Interventions
DRUGremifentanil
DRUGnitroprusside
Sponsors
Jeju National University School of Medicine
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
20 Years to 60 Years
Healthy volunteers
No
Inclusion criteria
* Patients who underwent endoscopic sinus surgery
Exclusion criteria
* patient who took any drug to influence this study * patient with cardiovascular disease, renal disease or liver disease
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Cardiac index | Cardiac index was continuously measured during controlled hypotension, an average of 90 min | Cardiac index was continuously measured during controlled hypotension using noninvasive cardiac output monitor. The average of cardiac index during controlled hypotension was compared with baseline value. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Total peripheral resistance index | Total peripheral resistance index was continuously measured during controlled hypotension, an average of 90 min | Total peripheral resistance index was continuously measured during controlled hypotension using noninvasive cardiac output monitor. The average of total peripheral resistance index during controlled hypotension was compared with baseline value. |
Other
| Measure | Time frame | Description |
|---|---|---|
| Stroke volume index | Stroke volume index was continuously measured during controlled hypotension, an average of 90 min | Stroke volume index was continuously measured during controlled hypotension using noninvasive cardiac output monitor. The average of stroke volume index during controlled hypotension was compared with baseline value. |
Countries
South Korea
Outcome results
None listed