Neomycin

DRUG19 trials

Sponsors

National Taiwan University Hospital, University of Dundee, Mark Pimentel, MD, UPECLIN HC FM Botucatu Unesp, Cedars-Sinai Medical Center

Conditions

Antibiotic Prophylaxis SurgeryBiliary AtresiaBowel ObstructionChronic Heart FailureColitis, UlcerativeColonization, AsymptomaticColorectal NeoplasmsColostomy

Early Phase 1

Role of Methane in Glycemic Control

CompletedNCT01638429

Cedars-Sinai Medical CenterDiabetes, Obesity

Start: 2012-04-30End: 2014-04-30Updated: 2019-05-02

Neomycin and Metronidazole Hydrochloride With or Without Polyethylene Glycol in Reducing Infection in Patients Undergoing Elective Colorectal Surgery

Thomas Jefferson UniversityColorectal Neoplasms, Diverticulitis, Inflammatory Bowel Diseases +1

Start: 2016-09-30End: 2021-10-31Target: 224Updated: 2018-08-22

Phase 1

Effect of Neomycin on the Pharmacokinetics of Regorafenib

CompletedNCT02001909

Start: 2013-12-31End: 2014-04-30Updated: 2015-08-13

Intestinal Microbiota Transplantation in Patients With Chronic Heart Failure

RecruitingNCT07490054

Melana Yuzefpolskaya, MDChronic Heart Failure

Start: 2025-09-01End: 2026-11-01Target: 40Updated: 2026-03-24

Phase 2

Eradication of Antibiotic-resistant Bacteria Through Antibiotics and Fecal Bacteriotherapy

Stephen HarbarthIntestinal Colonization With Multidrug-resistant Bacteria

Start: 2016-02-29End: 2018-03-31Updated: 2017-12-07

Interventional Bioremediation of Microbiota in Metabolic Syndrome

TerminatedNCT02730962

University of MinnesotaPre-Diabetes

Start: 2016-06-30End: 2018-01-31Updated: 2023-02-22

Fundamental Modification of the Gut Microbiota in the Treatment of Refractory Crohn's Disease

CompletedNCT02765256

University of PennsylvaniaCrohn's Disease

Start: 2016-08-31End: 2018-12-31Updated: 2024-02-06

Pilot Study of Fundamental Modification of the Gut Microbiota in the Treatment of Refractory Crohn's Disease

CompletedNCT03476317

Children's Hospital of PhiladelphiaCrohn Disease

Start: 2018-07-12End: 2020-12-31Updated: 2022-02-09

Fecal Microbiota Transplant and Re-introduction of Anti-PD-1 Therapy (Pembrolizumab or Nivolumab) for the Treatment of Metastatic Colorectal Cancer in Anti-PD-1 Non-responders

Active, not recruitingNCT04729322

M.D. Anderson Cancer CenterMetastatic Colorectal Adenocarcinoma, Metastatic Small Intestinal Adenocarcinoma, Stage IVA Colorectal Cancer AJCC v8 +4

Start: 2021-02-22End: 2027-12-31Updated: 2025-12-23

Phase 4

Decolonization of Carbapenem-resistant Enterobacterales (CRE) in Patients With Faecal Carriage of CRE With Neomycin

Mahidol UniversityColonization, Asymptomatic

Start: 2022-11-24End: 2024-03-31Target: 60Updated: 2022-11-30

Unknown Phase

Use of Probiotics to Prevent Cholangitis in Children With Biliary Atresia After the Kasai Portoenterostomy

CompletedNCT00166868

National Taiwan University HospitalBiliary Atresia

Start: 2003-12-31End: 2012-07-31Updated: 2013-08-21

Antibiotics for the Treatment of Ulcerative Colitis

CompletedNCT00355602

University of DundeeColitis, Ulcerative

Start: 2006-07-31End: 2008-12-31Target: 40Updated: 2009-02-11

Neomycin and Rifaximin Plus Neomycin in Treating Methane Positive Constipation Predominant Irritable Bowel Syndrome

CompletedNCT00945334

Mark Pimentel, MDConstipation-predominant Irritable Bowel Syndrome

Start: 2009-08-31End: 2013-06-30Updated: 2015-08-10

Comparison Between Erythromycin and Neomycin Treatment of Hepatic Encephalopathy

UPECLIN HC FM Botucatu UnespHepatic Encephalopathy, Hypertension, Portal, Liver Cirrhosis

Start: 2008-06-30End: 2010-12-31Updated: 2010-04-28

Systems Biology of Flu Vaccine in Healthy Adults With and Without the Use of Antibiotics

CompletedNCT02154061

Emory UniversityInfluenza

Start: 2015-04-30End: 2017-05-26Updated: 2018-08-15

Efficacy of Intestinal Decontamination in Patients Colonized by Carbapenem-resistant Klebsiella Pneumoniae and Colistin

CompletedNCT02604849

Maimónides Biomedical Research Institute of CórdobaPatients Colonized by Klebsiella Pneumoniae.

Start: 2012-07-31End: 2015-11-30Updated: 2015-11-13

Study of interactions between intestinal microflora, intestinal macrofauna and antibiotic use in adults living in Lambaréné, Gabon

Active, not recruitingPACTR201707002361207

Centre de Recherches Médicales de Lambaréné (CERMEL), Albert Schweitzer Hospital Lambaréné, GabonDigestive System Gut Flora and fauna

Start: 2015-10-05Target: 40Updated: 2026-01-27

Bowel Preparation in Elective Pediatric Colorectal Surgery

McMaster UniversityBowel Obstruction, Colostomy, Elective Surgery +4

Start: 2022-01-01End: 2024-01-30Target: 81Updated: 2021-12-09

Do Topical Antibiotics Improve Skin Graft Results?

CompletedNCT07286851

LAMB ProjectAntibiotic Prophylaxis Surgery, Skin Transplantation, Wounds and Injuries

Start: 2024-12-01End: 2025-08-31Updated: 2025-12-16

Related Papers

Pre-operative mechanical bowel preparation and prophylactic oral antibiotics for pediatric patients undergoing elective colorectal surgery: a protocol for a randomized controlled feasibility trial.

2024-05-25

A 5-day course of oral antibiotics followed by faecal transplantation to eradicate carriage of multidrug-resistant Enterobacteriaceae: a randomized clinical trial.

2019-01-04127 citations

Fecal microbiota transplantation against intestinal colonization by extended spectrum beta-lactamase producing Enterobacteriaceae: a proof of principle study.

2018-03-2272 citations

Oral decontamination with aminoglycosides is associated with lower risk of mortality and infections in high-risk patients colonized with colistin-resistant, KPC-producing Klebsiella pneumoniae.

2016-07-2633 citations