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Enbrel 50 mg solution for injection in pre-filled syringe

DRUG9 trials

Sponsors

Janssen - Cilag International, Giannina Gaslini Institute For Scientific Hospitalization And Care, Mabxience Research S.L., Universitair Medisch Centrum Utrecht, Erasmus Universitair Medisch Centrum Rotterdam (Erasmus MC)

Conditions

Chronic Plaque PsoriasisJuvenile Idiopathic ArthritisJuvenile idiopathic arthritisPsoriatic arthritisRheumatoid ArthritisRheumatoid arthritisRheumatoid arthritis according to 2010 criteriaSAPHO syndrome (synovitis

Phase 2

A multicenter, randomized, double-blind clinical trial evaluating the efficacy and safety of etanercept versus placebo in the treatment of patients with SAPHO syndrome
RecruitingCTIS2024-516919-25-00
Narodowy Instytut Geriatrii Reumatologii I Rehabilitacji Im Prof. Dr Hab. Med. Eleonory Reicheracne, hyperostosis, limiting the daily activity of patients. About half of patients present also with symptoms of severe axial spondyloarthritis. It can also lead to local bone destruction (usually sternoclavicular joints). +3
Start: 2024-10-22Target: 60Updated: 2024-10-31

Phase 3

A Phase 3, Multicenter, Randomized, Placebo- and Active Comparator-Controlled Study Evaluating the Efficacy, Safety, and Pharmacokinetics of Subcutaneously Administered Guselkumab for the Treatment of Chronic Plaque Psoriasis in Pediatric Participants (≥6 To <18 Years of Age)
Active, not recruitingCTIS2023-503378-19-00
Janssen - Cilag InternationalChronic Plaque Psoriasis
Start: 2018-08-23Target: 97Updated: 2026-01-15
A Prospective, Randomized, Double-blind, Parallel-group Study to Compare the Efficacy, Safety, Pharmacokinetics, and Immunogenicity of MB04 and EU-sourced Enbrel® in Patients with Moderate to Severe Rheumatoid Arthritis.
Active, not recruitingCTIS2024-510826-16-00
Mabxience Research S.L.Rheumatoid Arthritis
Start: 2025-04-07Target: 548Updated: 2025-12-17
Comparison of STep-up and step-down therapeutic strategies in childhood ARthritiS
Not yet recruitingCTIS2023-505051-43-00
Giannina Gaslini Institute For Scientific Hospitalization And Carejuvenile idiopathic arthritis
Target: 260Updated: 2025-09-30
Trial of Sequential Medications AfteR TNFi Failure in Juvenile Idiopathic Arthritis (SMART-JIA)
Not yet recruitingCTIS2025-520923-25-00
Duke Clinical Research InstituteJuvenile Idiopathic Arthritis
Target: 30Updated: 2026-02-11

Phase 4

A stratification trial to determine key immunological factors predicting Tofacitinib efficacy in Psoriatic Arthritis (PsA); TOFA-PREDICT
CompletedCTIS2024-510903-12-00
Universitair Medisch Centrum UtrechtPsoriatic arthritis
End: 2025-12-08Target: 160Updated: 2024-09-06
PeRsonalIzed MEdicine in Rheumatoid Arthritis (PRIMERA trial): a multicenter, open-label, randomized controlled trial comparing usual care with a tailor-made approach
Not yet recruitingCTIS2024-511530-12-01
Erasmus Universitair Medisch Centrum Rotterdam (Erasmus MC)Rheumatoid arthritis according to 2010 criteria
Target: 300Updated: 2024-10-01
Toward personalized medicine to guide drug withdrawal in children with juvenile idiopathic arthritis in clinical remission: a randomized clinical trial comparing early versus late drug withdrawal combining imaging and multi-Omics.
RecruitingCTIS2024-514732-24-00
IRCCS Istituto Giannina GasliniJuvenile idiopathic arthritis
Start: 2025-04-28Target: 328Updated: 2025-08-26
DISCO-RA:DIScontinuation of COncomitant disease modifying anti-rheumatic drugs (DMARDs) in rheumatoid arthritis patients also using TNF inhibitors - a randomized long-term non-inferiority strategy trial
Not yet recruitingCTIS2026-525316-33-00
Sint Maartenskliniek StichtingRheumatoid arthritis
Target: 202Updated: 2026-06-09