SAPHO syndrome (synovitis, acne, pustulosis, hyperostosis, osteitis) is a rare disease in which arthritis and osteitis is accompanied by skin lesions such as pustular psoriasis or acne. SAPHO syndrome significantly reduces the quality of life of patients due to the chronic occurrence of pain, limiting the daily activity of patients. About half of patients present also with symptoms of severe axial spondyloarthritis. It can also lead to local bone destruction (usually sternoclavicular joints).
Conditions
Brief summary
Improvement in the scope of disease activity as assessed by the patient - a decrease in the overall disease activity as assessed by the patient on the VAS scale by min. 50% after 12 weeks and a decrease in pain assessed by the patient on the VAS scale by min. 50% after 12 weeks
Interventions
Sponsors
Narodowy Instytut Geriatrii Reumatologii I Rehabilitacji Im Prof. Dr Hab. Med. Eleonory Reicher
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Improvement in the scope of disease activity as assessed by the patient - a decrease in the overall disease activity as assessed by the patient on the VAS scale by min. 50% after 12 weeks and a decrease in pain assessed by the patient on the VAS scale by min. 50% after 12 weeks | — |
Countries
Poland
Outcome results
None listed