CLOXACILLIN
Sponsors
Region Oestergoetland, Rigshospitalet, Fundacion Publica Andaluza Para La Gestion De La Investigacion En Salud De Sevilla, Assistance Publique Hopitaux De Paris, Centre Hospitalier Universitaire De Nimes
Conditions
Bacteremia Due to Methicillin Susceptible Staphylococcus AureusCatheter related bloodstream infections due to Staphylococcus aureusDouble Lumen InfectionHemodialysisPatients with an infection of the osteosynthesis material implanted after a long bone fracturePeriprosthetic joint infectionPyogenic vertebral osteomyelitisSepsis
Phase 2
Phase 3
Staphylococcus Aureus Bacteremia Antibiotic Treatment Options
CompletedNCT01792804
Start: 2013-12-31End: 2020-03-26Updated: 2020-05-27
Efficacy of a Short-term Sequential Therapy in Non-complicated Catheter Related Bacteremia by Methicillin- Susceptible S.Aureus.
TerminatedNCT01875263
Start: 2013-05-31End: 2014-11-30Updated: 2015-08-07
Efficacy and safety of different antimicrobial DURATions for the treatment of Infections associated with Osteosynthesis Material implanted after long bone fractures (DURATIOM). Phase 3 pragmatic multicenter open labelled randomized trial.
Not yet recruitingCTIS2023-508442-18-00
Target: 364Updated: 2025-04-11
Randomized open-label controlled trial evaluating a single-dose intravenous Dalbavancin versus standard antibiotic therapy during catheterrelated bloodstream infections due to Staphylococcus aureus [DALICATH]
RecruitingCTIS2024-514952-34-00
Start: 2023-06-23Target: 406Updated: 2025-04-23
Phase 4
Kan skattning av njurfunktion (eGFR) förutsäga vilka patienter med S. aureus-bakteremi som behöver justerad dosering via monitorering av kloxacillinkoncentrationer i plasma (TDM)?
RecruitingCTIS2023-505148-20-00
Start: 2024-06-01Target: 90Updated: 2023-11-24
Early shift to oral antibiotic treatment of pyogenic vertebral osteomyelitis – a open label non-inferiority randomized nationwide study.
RecruitingCTIS2023-507617-96-01
Start: 2024-02-14Target: 530Updated: 2025-01-08
Comparison of Cloxacillin and Benzylpenicillin in Penicillin Susceptible S. Aureus Bacteraemia
RecruitingNCT06726395
Start: 2025-03-10End: 2028-07-31Target: 420Updated: 2025-03-12
Aminoglycosides in early sepsis (AGES): A randomized pragmatic clinical trial comparing gentamicin and narrow spectrum betalactams to broad spectrum betalactams as empirical treatment in patients with suspected sepsis
Not yet recruitingCTIS2024-519797-39-00
Target: 2000Updated: 2025-12-19
The DALBA-study
Introduction of the antibiotic dalbavancin in orthopaedic surgery – an evaluation of:
• Health economic costs
• Patient-reported outcomes on quality of life
• Local bone and soft tissue concentrations
• Effect on the gut microbiome
A randomised controlled study of dalbavancin versus standard antibiotic treatment of Gram-positive periprosthetic joint infections.
RecruitingCTIS2025-522088-13-00
Start: 2025-12-12Target: 50Updated: 2025-12-05
Defining Antibiotic Levels in Intensive care patients (DALI-2) protocol - A multi-national pharmacokinetic/pharmacodynamic cohort study
to determine whether contemporary antibiotic dosing for critically ill patients achieves therapeutic exposures.
Not yet recruitingCTIS2024-516232-10-00
Target: 200Updated: 2025-10-17
Unknown Phase
Cloxacillin as Prevention of Double Lumen Infection in Hemodialysis Patients
CompletedNCT00885300
Start: 2008-01-31End: 2008-09-30Updated: 2009-04-21
Non-inferiority Trial Comparing Cloxacillin vs Cefazolin in Methicillin-susceptible Staphylococcus Aureus Bacteremia
CompletedNCT03248063
Start: 2018-09-05End: 2025-03-10Updated: 2025-11-24