Cloxacillin as Prevention of Double Lumen Infection in Hemodialysis Patients

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT00885300

Enrollment

100

Registered

2009-04-21

Start date

2008-01-31

Completion date

2008-09-30

Last updated

2009-04-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Double Lumen Infection, Hemodialysis

Brief summary

The purpose of this study is to investigate whether cloxacillin lock is effective in prevention of double lumen infection.

Detailed description

Double lumen infection is one of the causes of morbidity and mortality in hemodialysis patients. Many strategies used to prevent it and one of them is antibiotic lock. Thus we select chronic hemodialysis patients and divided them into 2 groups. One group received cloxacillin and heparin as catheter lock and the second group received only heparin lock.

Interventions

DRUGcloxacillin

cloxacillin 100mg/ml as catheter lock at the end of hemodialysis

DRUGheparin

heparin 1000iu/ml as catheter lock at the end of hemodialysis

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

PREVENTION

Masking

DOUBLE (Subject, Investigator)

Eligibility

Sex/Gender

ALL

Age

18 Years to 70 Years

Healthy volunteers

Yes

Inclusion criteria

* hemodialysis for 3 months * at least 2 time dialysis/week

Exclusion criteria

* active infection * acute renal failure

Design outcomes

Primary

Measure	Time frame
catheter infection	6 months

Countries

Iran

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026