Marginal Zone Lymphomas refractory to or in first or greater relapse after prior systemic therapy
Conditions
Brief summary
Complete response rate (CR) as best response to treatment, defined according to the international Revised Response Criteria for Malignant Lymphoma . For patients with SMZL, response is defined according to Matutes et al. 2008 and for patients with gastric lymphomas, histological response is evaluated according to GELA scoring system
Detailed description
Adverse events type and severity according to CTCAE v5.0 and relationship to study treatment, Overall response rate (ORR), Progression free survival (PFS), Duration of response (DOR), Overall survival (OS)
Interventions
Sponsors
Association International Extranodal Lymphoma Study Group (IELSG)
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Complete response rate (CR) as best response to treatment, defined according to the international Revised Response Criteria for Malignant Lymphoma . For patients with SMZL, response is defined according to Matutes et al. 2008 and for patients with gastric lymphomas, histological response is evaluated according to GELA scoring system | — |
Secondary
| Measure | Time frame |
|---|---|
| Adverse events type and severity according to CTCAE v5.0 and relationship to study treatment, Overall response rate (ORR), Progression free survival (PFS), Duration of response (DOR), Overall survival (OS) | — |
Countries
Austria, Italy
Outcome results
None listed