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MINJUVI 200 mg powder for concentrate for solution for infusion

DRUG14 trials

Sponsors

Incyte Corp., LYSARC, Incyte Corp., Incyte Corp., Karolinska University Hospital, Universitaetsklinikum Tuebingen AöR, Universitaetsklinikum Tuebingen AöR

Conditions

Advanced malignancies and IAI diseasesAutoimmune hemolytic anemiaAutoimmune thrombocytopeniaDiffuse Large B-Cell LymphomaDiffuse large B-cell lymphoma (DLBCL)Diffuse large B-cell lymphoma) and aggressive B-cell lymphomas (HGBCLDiffuse large B-cell lymphomas (DLBCLFollicular lymphoma

Phase 1

Phase 2

INCB 50465-801: A Phase 2, Open-Label, Multicenter, Rollover Study to Provide Continued Treatment for Participants Previously Enrolled in Studies of Parsaclisib (INCB050465)
RecruitingCTIS2022-501687-18-00
Incyte Corp.Advanced malignancies and IAI diseases
Start: 2020-10-28Target: 62Updated: 2025-07-07
VERLEN - Phase II, Open-Label Study evaluating efficacy of Lenalidomide and Tafasitamab combination associated to Rituximab in frontline Diffuse Large B-Cell Lymphoma Patients of 80 y/o or older
Active, not recruitingCTIS2023-507286-25-00
LYSARCDiffuse Large B-Cell Lymphoma
Start: 2021-12-23Target: 45Updated: 2025-12-30
Phase II trial of acalabrutinib in combination with tafasitamab in patients with previously treated marginal zone lymphomas (MZL)
Active, not recruitingCTIS2024-514122-23-00
Association International Extranodal Lymphoma Study Group (IELSG)Marginal Zone Lymphomas refractory to or in first or greater relapse after prior systemic therapy
Start: 2021-10-07Target: 22Updated: 2025-12-08
A prospective, multicenter phase II trial investigating Gemcitabine/Oxaliplatin/Rituximab with Tafasitamab (MOR208) for patients with relapsed/refractory transformed or Aggressive Lymphoma (GOAL II)
Active, not recruitingCTIS2024-514775-17-00
Universitaetsmedizin der Johannes Gutenberg-Universitaet Mainz KöRMalignant B-cell lymphoma
Start: 2021-02-10Target: 64Updated: 2024-08-22
A phase II efficacy and safety study of cell-free circulating tumor DNA-guided commencement of second-line treatment in patients with DLBCL/HGBCL relapse
Not yet recruitingCTIS2024-518275-64-00
Instytut Hematologii I TransfuzjologiiDiffuse large B-cell lymphoma) and aggressive B-cell lymphomas (HGBCL, Diffuse large B-cell lymphomas (DLBCL, High-grade B-cell lymphoma) originate from mature B-cells at various stages of terminal differentiation
Target: 340Updated: 2025-11-24
Primary treatment of follicular lymphoma with rituximab-lenalidomide-tafasitamab for high-risk disease and rituximab-lenalidomide with a 1:1 randomization to tafasitamab for low-risk disease: a phase II study – NLG-FL7
RecruitingCTIS2023-508196-36-00
Karolinska University HospitalFollicular lymphoma
Start: 2025-05-27Target: 270Updated: 2025-04-28
Response-adaptive to Epcoritamab In FIrst Relapse: A Phase II, response-adaptive, Open-Label, Multicenter Study to Evaluate the Efficacy of Eptoritamab in Patients with Relapse/Refractory Large B Cell Lymphoma
RecruitingCTIS2024-514440-86-00
Fundacion GeltamoRelapse/Refractory Large B Cell Lymphoma
Start: 2025-08-04Target: 80Updated: 2025-10-06
INCA000585-201 - A PHASE 2A, OPEN-LABEL, MULTI-CENTER STUDY OF TAFASITAMAB IN ADULT PARTICIPANTS WITH AUTOIMMUNE BLOOD CELL DISORDERS
Not yet recruitingCTIS2025-521286-27-00
Incyte Corp.Autoimmune hemolytic anemia, Autoimmune thrombocytopenia, Immune-mediated thrombocytopenia
Target: 15Updated: 2026-02-24

Phase 3

An Open-Label, Multicenter, Extension Study to Provide Continued Treatment for Patients with Hematologic Malignancies Previously Enrolled in Studies with Tafasitamab.
RecruitingCTIS2022-500765-27-00
Incyte Corp.Hematologic malignancies
Start: 2022-11-03Target: 5Updated: 2026-01-11
A Phase 3, Single-Arm, Open-Label, Multicenter Study to Evaluate the Safety and Efficacy of Tafasitamab Plus Lenalidomide in Participants With Relapsed or Refractory Diffuse Large B-Cell Lymphoma
Active, not recruitingCTIS2023-505579-53-00
Incyte Corp.Diffuse large B-cell lymphoma (DLBCL)
Start: 2022-10-25Target: 74Updated: 2025-07-24
A Phase 3, Randomized, Double-Blind, Placebo-Controlled, Multicenter Study to Evaluate the Efficacy and Safety of Tafasitamab Plus Lenalidomide in Addition to Rituximab Versus Lenalidomide in Addition to Rituximab in Patients With Relapsed/Refractory (R/R) Follicular Lymphoma Grade 1 to 3a or R/R Marginal Zone Lymphoma
Active, not recruitingCTIS2023-504684-16-00
Incyte Corp.follicular lymphoma (FL) and marginal zone lymphoma (MZL)
Start: 2021-06-05Target: 345Updated: 2025-10-02
A phase 3, multicenter, randomized, double-blind, placebo-controlled trial comparing the efficacy and safety of tafasitamab plus lenalidomide in addition to R-CHOP versus R CHOP in previously untreated, high-intermediate and high-risk patients with newly-diagnosed diffuse large B-cell lymphoma (DLBCL) [frontMIND]
Active, not recruitingCTIS2022-500237-92-00
Incyte Corp.Newly-diagnosed high-intermediate and high-risk diffuse large B-cell lymphoma (DLBCL)
Start: 2021-04-23Target: 392Updated: 2025-06-02