MINJUVI 200 mg powder for concentrate for solution for infusion
Sponsors
Incyte Corp., LYSARC, Incyte Corp., Incyte Corp., Karolinska University Hospital, Universitaetsklinikum Tuebingen AöR, Universitaetsklinikum Tuebingen AöR
Conditions
Advanced malignancies and IAI diseasesAutoimmune hemolytic anemiaAutoimmune thrombocytopeniaDiffuse Large B-Cell LymphomaDiffuse large B-cell lymphoma (DLBCL)Diffuse large B-cell lymphoma) and aggressive B-cell lymphomas (HGBCLDiffuse large B-cell lymphomas (DLBCLFollicular lymphoma
Phase 1
A Phase 1b/2, Open-Label, Multicenter Study to Evaluate the Safety and Pharmacokinetics of a Modified Tafasitamab IV Dosing Regimen Combined with Lenalidomide (LEN) in Patients with Relapsed or Refractory Diffuse Large B-Cell Lymphoma (R/R DLBCL) (MINDway)
Active, not recruitingCTIS2023-507993-42-00
Start: 2022-03-17Target: 38Updated: 2025-07-07
A Prospective Phase I/II, Single-Arm, Open-Label, Multicentre Study to Evaluate the Safety and Efficacy of Tafasitamab (MOR00208) in Pediatric Patients with Relapsed or Refractory Acute B Lineage Leukemia
RecruitingCTIS2024-511336-28-00
Start: 2023-08-11Target: 20Updated: 2024-08-15
Phase 2
INCB 50465-801:
A Phase 2, Open-Label, Multicenter, Rollover Study to Provide Continued Treatment for Participants Previously Enrolled in Studies of Parsaclisib (INCB050465)
RecruitingCTIS2022-501687-18-00
Start: 2020-10-28Target: 62Updated: 2025-07-07
VERLEN - Phase II, Open-Label Study evaluating efficacy of Lenalidomide and Tafasitamab combination associated to Rituximab in frontline Diffuse Large B-Cell Lymphoma Patients of 80 y/o or older
Active, not recruitingCTIS2023-507286-25-00
Start: 2021-12-23Target: 45Updated: 2025-12-30
Phase II trial of acalabrutinib in combination with tafasitamab in patients with previously treated marginal zone lymphomas (MZL)
Active, not recruitingCTIS2024-514122-23-00
Start: 2021-10-07Target: 22Updated: 2025-12-08
A prospective, multicenter phase II trial investigating Gemcitabine/Oxaliplatin/Rituximab with Tafasitamab (MOR208) for patients with relapsed/refractory transformed or Aggressive Lymphoma (GOAL II)
Active, not recruitingCTIS2024-514775-17-00
Start: 2021-02-10Target: 64Updated: 2024-08-22
A phase II efficacy and safety study of cell-free circulating tumor DNA-guided commencement of second-line treatment in patients with DLBCL/HGBCL relapse
Not yet recruitingCTIS2024-518275-64-00
Target: 340Updated: 2025-11-24
Primary treatment of follicular lymphoma with rituximab-lenalidomide-tafasitamab for high-risk disease and rituximab-lenalidomide with a 1:1 randomization to tafasitamab for low-risk disease: a phase II study – NLG-FL7
RecruitingCTIS2023-508196-36-00
Start: 2025-05-27Target: 270Updated: 2025-04-28
Response-adaptive to Epcoritamab In FIrst Relapse: A Phase II, response-adaptive, Open-Label, Multicenter Study to Evaluate the Efficacy of Eptoritamab in Patients with Relapse/Refractory Large B Cell Lymphoma
RecruitingCTIS2024-514440-86-00
Start: 2025-08-04Target: 80Updated: 2025-10-06
INCA000585-201 - A PHASE 2A, OPEN-LABEL, MULTI-CENTER STUDY OF TAFASITAMAB IN ADULT PARTICIPANTS WITH AUTOIMMUNE BLOOD CELL DISORDERS
Not yet recruitingCTIS2025-521286-27-00
Target: 15Updated: 2026-02-24
Phase 3
An Open-Label, Multicenter, Extension Study to Provide Continued Treatment for Patients with Hematologic Malignancies Previously Enrolled in Studies with Tafasitamab.
RecruitingCTIS2022-500765-27-00
Start: 2022-11-03Target: 5Updated: 2026-01-11
A Phase 3, Single-Arm, Open-Label, Multicenter Study to Evaluate the Safety and Efficacy of Tafasitamab Plus Lenalidomide in Participants With Relapsed or Refractory Diffuse Large B-Cell Lymphoma
Active, not recruitingCTIS2023-505579-53-00
Start: 2022-10-25Target: 74Updated: 2025-07-24
A Phase 3, Randomized, Double-Blind, Placebo-Controlled, Multicenter Study to Evaluate the Efficacy and Safety of Tafasitamab Plus Lenalidomide in Addition to Rituximab Versus Lenalidomide in Addition to Rituximab in Patients With Relapsed/Refractory (R/R) Follicular Lymphoma Grade 1 to 3a or R/R Marginal Zone Lymphoma
Active, not recruitingCTIS2023-504684-16-00
Start: 2021-06-05Target: 345Updated: 2025-10-02
A phase 3, multicenter, randomized, double-blind, placebo-controlled trial comparing the efficacy and safety of tafasitamab plus lenalidomide in addition to R-CHOP versus R CHOP in previously untreated, high-intermediate and high-risk patients with newly-diagnosed diffuse large B-cell lymphoma (DLBCL) [frontMIND]
Active, not recruitingCTIS2022-500237-92-00
Start: 2021-04-23Target: 392Updated: 2025-06-02