Tranexamic acid,Placebo

5 trials

Sponsors

Chnburi Hospital, none, Khonkaen hospital, Faculty of Medicine Siriraj Hospital, Rajavithi Hospital

Conditions

Coagulation system alterations and venous thromboembolism risk associated with oral tranexamic acid treatment for facial melasma Melasma, Tranexamic Acid, Thrombelastography, Blood Coagulation, Venous ThrombosisDistal Femur Fractures Intraoperative Blood Loss Distal Femur Fractures Blood Loss Tranexamic AcidPatient who underwent a total hysterectomy with or without adnexal surgery for benign uterine diseases with risk difficult operation for benign hysterectomy Difficult operation,Hysterectomy,Intraoperative blood loss ,Excessive blood loss,Tranexamic acidTo determine the benefits of prophylactic tranexamic acid administration in preventing the decline of postoperative hemoglobin levels, minimizing intraoperative blood loss, and reducing the necessity for blood transfusions. Decreased intraoperative bleeding enhances surgical field visualization, thereby improving surgical safety, minimizing the destruction of healthy ovarian tissue, and reducing the utilization of electrosurgical coagulation. Consequently, this limits thermal injury to the adjacintraoperative blood loss in pregnant woman undergoes caesarean section due to placenta previa Keyword: Tranexamic acid, preoperative, placenta previa, intraoperative blood loss, caesarean section

Phase 2

The Efficacy of Tranexamic Acid to Reduce Perioperative Blood Loss and Blood Transfusion in Patients Undergoing Distal Femur Fracture Surgery

Active, not recruitingTCTR20220104001

Chnburi HospitalDistal Femur Fractures Intraoperative Blood Loss Distal Femur Fractures Blood Loss Tranexamic Acid

Start: 2019-07-01Target: 60Updated: 2026-08-03

Efficacy of Preoperative Intravenous Tranexamic Acid Before Caesarean Section in Placenta Previa

Active, not recruitingTCTR20220930003

noneintraoperative blood loss in pregnant woman undergoes caesarean section due to placenta previa Keyword: Tranexamic acid, preoperative, placenta previa, intraoperative blood loss, caesarean section

Start: 2021-07-01Target: 60Updated: 2026-08-03

Phase 3

Efficacy of Preoperative Intravenous Tranexamic Acid to Reduce Blood Loss in Difficult Benign Hysterectomy : A Randomized Double-Blind Placebo-Controlled Trial

Active, not recruitingTCTR20250206001

Khonkaen hospitalPatient who underwent a total hysterectomy with or without adnexal surgery for benign uterine diseases with risk difficult operation for benign hysterectomy Difficult operation,Hysterectomy,Intraoperative blood loss ,Excessive blood loss,Tranexamic acid

Start: 2024-09-23Target: 50Updated: 2026-08-03

Evaluation of hemostatic profiles in patients with melasma treated with oral tranexamic acid: A randomized controlled trial

Active, not recruitingTCTR20260327002

Faculty of Medicine Siriraj HospitalCoagulation system alterations and venous thromboembolism risk associated with oral tranexamic acid treatment for facial melasma Melasma, Tranexamic Acid, Thrombelastography, Blood Coagulation, Venous Thrombosis

Start: 2026-04-27Target: 40Updated: 2026-08-03

Phase 4

Effect of Prophylactic Intravenous Tranexamic Acid on Postoperative Hemoglobin Level After Laparoscopic Cystectomy for Ovarian Endometrioma: A Randomized Controlled Trial

Active, not recruitingTCTR20260604009

Rajavithi HospitalTo determine the benefits of prophylactic tranexamic acid administration in preventing the decline of postoperative hemoglobin levels, minimizing intraoperative blood loss, and reducing the necessity for blood transfusions. Decreased intraoperative bleeding enhances surgical field visualization, thereby improving surgical safety, minimizing the destruction of healthy ovarian tissue, and reducing the utilization of electrosurgical coagulation. Consequently, this limits thermal injury to the adjac

Start: 2026-06-03Target: 46Updated: 2026-08-03