Tizanidine

DRUG16 trials

Conditions

AnaesthesiaBack PainChronic PainCognitive ImpairmentHealthyHearingInsomnia Due to Medical ConditionLevobupicaine

Early Phase 1

Effect of Neural Constraints on Movement in Stroke

RecruitingNCT06666673

Northwestern UniversityStroke

Start: 2024-08-23End: 2029-07-31Target: 64Updated: 2025-05-14

Phase 1

Bioequivalence Study of Tizanidine HCl 4mg Tablets of Dr.Reddy's Under Fed Conditions

CompletedNCT01065987

Dr. Reddy's Laboratories LimitedHealthy

Start: 2001-09-30End: 2001-11-30Updated: 2010-02-10

Bioequivalence Study of Tizanidine HCl Tablets 4 mg of Dr.Reddys Under Fasting Conditions

CompletedNCT01146028

Dr. Reddy's Laboratories LimitedHealthy

Start: 2001-09-30End: 2001-11-30Updated: 2012-01-13

A Study on the Effect of Vemurafenib on the Pharmacokinetics of a Single Dose of Tizanidine in Patients With BRAFV600 Mutation-Positive Metastatic Malignancies

CompletedNCT01844674

Hoffmann-La RocheMalignant Melanoma, Neoplasms

Start: 2013-09-02End: 2014-08-26Updated: 2017-03-20

Phase 2

A Study to Define the ECG Effects of Tizanidine Compared to Placebo and the Positive Control, Moxifloxacin, in Healthy Men and Women Using a Blinded ECG Evaluator: A Thorough ECG Trial

CompletedNCT01839279

Acorda TherapeuticsSpasticity

Start: 2013-04-30End: 2014-05-31Updated: 2021-03-23

Gabapentin and Tizanidine for Insomnia in Chronic Pain

CompletedNCT04429347

University of California, San DiegoChronic Pain, Insomnia Due to Medical Condition

Start: 2020-07-29End: 2024-12-01Updated: 2025-01-03

Phase 3

CARES-Spine (Comprehensive Analgesic, Recovery, and Education Support for Spine Surgery) Trial

RecruitingNCT06027099

Stanford UniversityBack Pain, Chronic Pain, Neck Pain +1

Start: 2024-12-05End: 2028-07-31Target: 375Updated: 2025-09-30

Effect of Tizanidine on Postoperative Urinary Retention After Sacrospinous Suspension

CompletedNCT06258785

Endeavor HealthPostoperative Urinary Retention, Reconstructive Pelvic Surgery, Sacrospinous Vaginal Vault Suspension

Start: 2024-09-17End: 2025-10-24Updated: 2025-11-24

Phase 4

Tizanidine and Pain After Herniorrhaphy

CompletedNCT02016443

Diskapi Teaching and Research HospitalUnilateral Inguinal Hernia

Start: 2013-11-30End: 2014-06-30Updated: 2015-04-23

Tizanidine and Superficial Cervical Block on Pain After Thyroidectomy

CompletedNCT02725359

Ataturk UniversityThyroidectomy

Start: 2016-04-30End: 2016-12-31Updated: 2016-12-20

Ibuprofen Plus Metaxolone, Tizanidine, or Baclofen for Low Back Pain

CompletedNCT03068897

Montefiore Medical CenterLow Back Pain

Start: 2017-05-03End: 2018-10-11Updated: 2020-08-12

Opioid-Free Pain Protocol After Shoulder Arthroplasty

Active, not recruitingNCT05488847

Henry Ford Health SystemShoulder Arthropathy, Shoulder Pain

Start: 2022-06-25End: 2026-09-01Updated: 2026-02-10

Assess the Effect of Metaxalone 640 mg (M640) Compared to Tizanidine 8 mg on Truck Driving Ability and Cognition

CompletedNCT06382662

Primus PharmaceuticalsCognitive Impairment

Start: 2024-04-29End: 2025-03-06Updated: 2025-08-22

Comparison of Analgesic Efficacy of Intrathecal Levobupivacaine With and Without Oral Tizanidine in Lower Limb Surgeries: A Prospective Randomized Study

CompletedNCT07310628

All India Institute of Medical SciencesLevobupicaine, Lower Limb Surgery, Pain, Chronic +1

Start: 2022-08-20End: 2025-08-20Updated: 2026-01-09

Unknown Phase

Melatonin Versus Tizanidine with Cervical Plexus Block for Thyroidectomy

RecruitingPACTR202503835746796

AuthorsAnaesthesia

Start: 2025-02-26Target: 54Updated: 2026-01-27

Tizanidine and Acoustic Reflex

RecruitingNCT07309354

Uşak UniversityHearing, Reflex, Acoustic

Start: 2025-07-15End: 2026-03-15Target: 45Updated: 2025-12-30

Related Papers

Ultrasound-guided bilateral superficial cervical block and preemptive single-dose oral tizanidine for post-thyroidectomy pain: a randomized-controlled double-blind study.

2018-02-2116 citations

Tizanidine for the management of acute postoperative pain after inguinal hernia repair

European Journal of Anaesthesiology2015-11-1337 citations