Sulfadoxine pyrimethamine

DRUG17 trials

Sponsors

Makerere University, Albert Schweitzer Hospital, Netherlands, University of Bamako, Radboud University Medical Center, Federal Medical Centre, Owo

Conditions

AnemiaAnemia in ChildrenAntepartum DepressionChild DevelopmentControlled Human Malaria InfectionEnvironmental Enteric DysfunctionGametocytesIntegrated Control

Phase 3

Sulfadoxine- Pyrimethamine Versus Weekly Chloroquine for Malaria Prevention in Children With Sickle Cell Anemia

CompletedNCT00399074

Makerere UniversityMalaria, Sickle Cell Anemia

Start: 2006-10-31End: 2007-02-28Target: 220Updated: 2009-07-02

Comparison of ISTp- PYRAMAX-US-RDT to IPTp-SP to Prevent Malaria in Pregnant Women in DRC (ULTRAPYRAPREG)

CompletedNCT04783051

University of KinshasaMalaria in Pregnancy

Start: 2021-05-06End: 2022-06-22Updated: 2022-11-04

Effectiveness, Feasibility and Acceptability of Seasonal Malaria Chemoprevention in Aweil South County in South Sudan

Malaria ConsortiumMalaria

Start: 2022-07-18End: 2024-12-31Target: 3575Updated: 2024-03-25

Dihydroartemisinin-piperaquine + sulfadoxine-pyrimethamine for sickle cell anemia

Active, not recruitingPACTR202507605302954

Thrasher Research FundMalaria Sickle cell anemia and febrile illnesses

Start: 2025-07-01Target: 232Updated: 2026-01-27

Phase 4

Efficacy of Sulfadoxine-Pyrimethamine for Treating Malaria in Gabonese Children

TerminatedNCT00453856

Albert Schweitzer Hospital, NetherlandsMalaria

Start: 2007-03-31Target: 139Updated: 2007-08-10

Reduction of low birth weight at delivery through the adjunction of oral azithromycin to the intermittent preventive treatment of malaria in pregnant women: a randomized controlled trial in rural Burkina Faso

RecruitingPACTR201808177464681

clinical research unit of nanoroMalaria Neonatal Diseases Pregnancy and Childbirth

Start: 2018-10-01Target: 942Updated: 2026-01-27

Chemoprevention Efficacy Study in Burkina Faso

Malaria ConsortiumMalaria

Start: 2022-07-15End: 2023-12-01Updated: 2023-11-01

Comparing Chemoprevention Drugs for School-based Malaria Control

CompletedNCT05980156

University of Maryland, BaltimoreAnemia in Children, Malaria,Falciparum

Start: 2023-02-13End: 2023-07-28Updated: 2023-08-07

Unknown Phase

Intermittent Preventive Treatment in Infant in Mali

CompletedNCT00766662

University of BamakoMalaria

Start: 2006-10-31End: 2007-12-31Updated: 2008-10-06

Controlled Human Malaria Infection Model for Evaluation of Transmission-blocking Interventions - Study 2

CompletedNCT03454048

Radboud University Medical CenterControlled Human Malaria Infection, Gametocytes, Malaria,Falciparum +1

Start: 2018-05-07End: 2018-11-20Updated: 2020-07-07

Azithromycin (AZ) and Sulphadoxine-pyrimethamine (SP) for Malaria Prevention in Pregnant Women (IPT-AZ/IPT-SP)

Federal Medical Centre, OwoMalaria in Pregnancy, Pregnancy

Start: 2019-06-01End: 2020-01-31Target: 168Updated: 2019-05-10

Gestational malaria in Kisangani: Efficacy of Mefloquine versus Sulfadoxine-Pyrimethamine in Intermittent Preventive Treatment

Active, not recruitingPACTR201905899965726

University of KisanganiMalaria Pregnancy and Childbirth

Start: 2019-05-01Target: 300Updated: 2026-01-27

Feasibility and Safety of Combining Anti-malarial With Deworming Drugs in African Children

London School of Hygiene and Tropical MedicineIntegrated Control, Malaria, Mass Drug Administration With Anthelminthic Drugs +3

Start: 2022-06-16End: 2023-09-30Target: 600Updated: 2022-07-14

Perennial Malaria Chemoprevention (PMC) in Côte D'Ivoire

Active, not recruitingNCT05856357

London School of Hygiene and Tropical MedicineAnemia, Malaria

Start: 2023-08-11End: 2025-09-30Target: 1568Updated: 2025-01-09

Perennial Malaria Chemoprevention (PMC) in Cameroon

Active, not recruitingNCT05889052

London School of Hygiene and Tropical MedicineAnemia, Malaria

Start: 2023-07-19End: 2025-09-30Target: 2080Updated: 2025-01-09

Improving Cognition and Gestational Duration With Targeted Nutrition

Active, not recruitingNCT05949190

Washington University School of MedicineAntepartum Depression, Child Development, Malnutrition in Pregnancy +2

Start: 2023-08-18End: 2026-10-01Updated: 2026-03-02

Eggs for Gut Health

CompletedNCT06002438

Washington University School of MedicineEnvironmental Enteric Dysfunction, Moderate Acute Malnutrition, Severe Acute Malnutrition +1

Start: 2023-10-09End: 2024-12-19Updated: 2025-02-06

Related Papers

Egg supplementation for 24 weeks does not improve linear growth or reduce small intestinal permeability in Sierra Leonean children with moderate wasting: a randomized, blinded, controlled trial.

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Intermittent screening using ultra-sensitive malaria rapid diagnostic test and treatment with pyronaridine-artesunate compared to standard preventive treatment with sulfadoxine-pyrimethamine for malaria prevention in pregnant women in Kinshasa, DRC

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Effectiveness of malaria chemoprevention in the first two years of life in Cameroon and Côte d'Ivoire compared to standard of care: study protocol for a population-based prospective cohort impact evaluation study.

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Feasibility and safety of integrating mass drug administration for helminth control with seasonal malaria chemoprevention among Senegalese children: a randomized controlled, observer-blind trial

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Effects of maternal antenatal treatment with two doses of azithromycin added to monthly sulfadoxine-pyrimethamine for the prevention of low birth weight in Burkina Faso: an open-label randomized controlled trial.

2023-03-178 citations

Comparison of intermittent screening (using ultra-sensitive malaria rapid diagnostic test) and treatment (using a newly registered antimalarial pyronaridine-artesunate-PYRAMAX®) to standard intermittent preventive treatment with sulfadoxine-pyrimethamine for the prevention of malaria in pregnant women living in endemic areas: ULTRAPYRAPREG.

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Safety and effectiveness of delivering mass drug administration for helminths through the seasonal malaria chemoprevention platform among Senegalese children: study protocol for a randomised controlled trial.

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A Randomized Clinical Trial to Compare <i>Plasmodium falciparum</i> Gametocytemia and Infectivity After Blood-Stage or Mosquito Bite–Induced Controlled Malaria Infection

The Journal of Infectious Diseases2020-03-3127 citations

The implementation of malaria intermittent preventive trialtreatment with sulphadoxine-pyrimethamine in infants reduced all-cause mortality in the district of Kolokani, Mali: results from a cluster randomized control.

2012-03-169 citations