solution injectable/pour perfusion
Sponsors
Centre hospitalier universitaire de Liege, Hospices Civils De Lyon, Fondation Franc.Cancerologie Digestive, Centre Hospitalier Universitaire Grenoble Alpes, Centre Hospitalier Universitaire De Bordeaux
Conditions
IntubationPatients in ICU with risks of Acute Respiratory Distress SyndromePatients undergoing craniotomy for supratentorial massPostoperative pain after a total knee arthroplastyResectable Gastric CancerResectable borderline pancreatic adenocarcinomaRespiratory distressSevere acute pain
Phase 1
Phase 2
Perioperative Treatment in Resectable Gastric Cancer with Spartalizumab (PDR001) in Combination with fluorouracil, leucovorin, oxaliplatin, and docetaxel (FLOT): A phase II study (GASPAR)
CompletedCTIS2024-516299-13-00
Start: 2024-09-06End: 2025-11-27Target: 68Updated: 2024-09-05
Evaluation of the efficacy of sphenopalatine block in headache in patients with non-traumatic subarachnoid hemorrhage (SAH) after training of neurosurgical intensive care nurses.
RecruitingCTIS2024-514282-19-00
Start: 2025-05-30Target: 70Updated: 2024-11-26
ENGIC - 01 COLOSOTO: A single-arm phase II study evaluating 5-fluorouracil plus Panitumumab (anti-EGFR) and Sotorasib (KRAS G12C inhibitor) in first-line treatment of patients non-eligible for a doublet/triplet chemotherapy with advanced unresectable KRAS G12C mutated colorectal adenocarcinoma
RecruitingCTIS2024-514030-20-00
Start: 2025-08-29Target: 37Updated: 2026-01-13
IMMUNORARE5 : A national platform of 5 academic phase II trials coordinated by Lyon university hospital to assess the safety and the efficacy of the IMMUNOtherapy with Domvanalimab + Zimberelimab combination in patients with advanced RARE cancers
SuspendedCTIS2024-517254-99-00
Start: 2025-09-16Target: 186Updated: 2026-01-07
PRODIGE 104 – NEOPREDICT
A multicenter phase II trial using transcriptomic signatures to personalize neoadjuvant chemotherapy for patients with resectable borderline pancreatic adenocarcinoma.
Not yet recruitingCTIS2024-519753-11-00
Target: 110Updated: 2025-10-17
Phase 3
Effectiveness of an Optimisation Strategy for Emergency Tracheal Intubation on postintubation Morbidity: A superiority cluster randomised controlled trial - OSETIM
RecruitingCTIS2024-514913-37-00
Start: 2023-01-12Target: 1500Updated: 2025-09-03
Randomized Clinical Trial of Inhaled Sedation with Sevoflurane in Critically Ill Patients at Risk of Developing the Acute Respiratory Distress Syndrome
RecruitingCTIS2024-517670-15-00
Start: 2023-07-24Target: 80Updated: 2025-11-10
Phase 4
Evaluation of the efficacy of Sphenopalatine Ganglion Block compared to Scalp Block in Supratentorial Intracranial Surgery : a Non-inferiority, Randomized, Controlled, Double-Blind Trial
RecruitingCTIS2024-512112-22-01
Start: 2024-12-04Target: 88Updated: 2024-09-06
Opioid-Free Analgesia In Intensive Care Unit : A Prospective, Monocentric, Randomized, Double-Blind, Feasibility Clinical Trial
Active, not recruitingCTIS2024-517770-14-00
Start: 2025-11-24Target: 50Updated: 2025-11-19
Randomized controlled double-blind study ESKAPE :
ESKetamine low-dose versus ketamine low-dose for Severe Acute Pain in Emergency Departments, comparison of PsychodyslEptic effects
RecruitingCTIS2024-518733-29-00
Start: 2025-04-29Target: 74Updated: 2025-05-27
SubSUF-ER - Management of moderate to severe monotraumatic pain with sublingual Sufentanil in an emergency situation.
RecruitingCTIS2024-519217-64-00
Start: 2025-04-22Target: 300Updated: 2025-03-21
Evaluation of postoperative recovery when combining intravenous lidocaine with ropivacaine infiltration in laparoscopic colorectal oncologic surgery: a randomized controlled trial
Not yet recruitingCTIS2025-523207-29-00
Target: 182Updated: 2025-12-17