Reproxalap Ophthalmic Solution (0.25%)
Sponsors
Aldeyra Therapeutics, Inc.
Conditions
Allergic ConjunctivitisConjunctivitis, AllergicDry EyeDry Eye DiseaseDry Eye SyndromeDry Eye Syndromes
Phase 1
A Methodology Development Environmental Clinical Trial of Reproxalap in Subjects With Seasonal Allergic Conjunctivitis
CompletedNCT03660878
Start: 2018-09-08End: 2019-11-19Updated: 2025-04-08
A Methodology Development Clinical Trial of Reproxalap in Subjects With Seasonal Allergic Conjunctivitis Using the Environmental Exposure Chamber
CompletedNCT03709121
Start: 2018-10-02End: 2019-03-20Updated: 2025-02-24
Phase 2
A Multi-Center, Randomized, Double Masked, Parallel-Group, Vehicle-Controlled, Clinical Study to Assess the Safety and Efficacy of Reproxalap Ophthalmic Solution in Subjects With Dry Eye Disease
CompletedNCT03404115
Start: 2018-01-02End: 2018-07-11Updated: 2025-02-06
The TRANQUILITY Trial: Clinical Trial to Assess the Efficacy and Safety in Subjects With Dry Eye Disease
CompletedNCT04674358
Start: 2020-11-21End: 2021-09-12Updated: 2025-03-19
A Clinical Trial to Assess Subjects With Dry Eye Disease.
CompletedNCT04971031
Start: 2021-06-15End: 2021-09-08Updated: 2025-02-24
An Exploratory Crossover Clinical Trial to Compare the Activity of Reproxalap and Lifitegrast in a Dry Eye Disease Chamber
CompletedNCT05102409
Start: 2021-09-09End: 2021-10-25Updated: 2025-02-28
A Clinical Trial to Evaluate the Safety and Efficacy of Rreproxalap in Adults With Dry Eye Disease
CompletedNCT05424549
Start: 2022-03-09End: 2022-05-09Updated: 2025-01-15
Phase 3
ALLEVIATE Trial - A Phase 3 Trial in Subjects With Allergic Conjunctivitis
CompletedNCT03494504
Start: 2018-03-30End: 2018-11-05Updated: 2025-02-11
The INVIGORATE Trial: A Clinical Trial to Assess the Efficacy and Safety of Subjects With Seasonal Allergic Conjunctivitis.
CompletedNCT04207736
Start: 2019-12-05End: 2021-02-16Updated: 2024-11-20
A Multi-Center, Double-Masked, Randomized, Vehicle-Controlled, Parallel-Group Clinical Trial Evaluating the Safety of Reproxalap Ophthalmic Solution in Subjects With Dry Eye Disease
CompletedNCT04735393
Start: 2021-01-26End: 2022-10-11Updated: 2025-11-26
The TRANQUILITY 2 Trial: A Phase 3 Clinical Trial to Assess the Efficacy and Safety in Subjects With Dry Eye Disease
CompletedNCT05062330
Start: 2021-08-28End: 2022-03-04Updated: 2025-03-18
The INVIGORATE 2 Trial: A Clinical Trial to Assess the Efficacy and Safety of Subjects With Seasonal Allergic Conjunctivitis
CompletedNCT05234554
Start: 2022-01-21End: 2023-04-22Updated: 2026-05-14
A Clinical Trial to Assess the Efficacy and Safety of Subjects With Dry Eye Disease
CompletedNCT06389214
Start: 2024-04-09End: 2024-06-11Updated: 2025-06-05
A Clinical Trial to Assess the Safety and Efficacy of Subjects With Dry Eye Disease
CompletedNCT06424444
Start: 2024-04-29End: 2024-11-03Updated: 2025-10-01
A Trial to Assess the Safety and Efficacy of Subjects With Dry Eye Disease
CompletedNCT06493604
Start: 2024-06-24End: 2025-02-27Updated: 2025-12-22