Radiochemotherapy

RADIATION15 trials

Sponsors

Polish Colorectal Cancer Study Group, Karolinska University Hospital, Federation Francophone de Cancerologie Digestive, Technische Universität Dresden, Center Eugene Marquis

Conditions

Adenocarcinoma of the Esophagus and Gastric CardiaAdjuvant TherapyAdvanced CancerAnusCarcinoma, Squamous CellConcurrent ChemoradiotherapyEpidermoid CarcinomaEsophageal Cancer Stage IIB

Phase 1

Radiochemotherapy With Panitumumab in the Localised Epidermoid Carcinoma of the Anus

CompletedNCT01581840

Federation Francophone de Cancerologie DigestiveAnus, Epidermoid Carcinoma

Start: 2016-01-31End: 2021-02-28Updated: 2024-07-01

Phase 2

Neoadjuvant Chemotherapy Versus Radiochemotherapy for Cancer of the Esophagus or Cardia

CompletedNCT01362127

Karolinska University HospitalAdenocarcinoma of the Esophagus and Gastric Cardia, Carcinoma, Squamous Cell

Start: 2006-10-31End: 2018-06-25Updated: 2020-02-26

NAC Followed by RH for the Treatment of LACC

Lei LiAdjuvant Therapy, Concurrent Chemoradiotherapy, Laparoscopy +6

Start: 2019-06-19End: 2025-06-01Target: 60Updated: 2019-06-20

JS207 Combined With Chemotherapy in Subjects With Stage II-III NSCLC

Not yet recruitingNCT06944470

Shanghai Junshi Bioscience Co., Ltd.NSCLC

Start: 2025-04-20End: 2027-12-31Target: 76Updated: 2025-04-25

Phase 3

Preoperative Radiotherapy and Local Excision in Rectal Cancer

Polish Colorectal Cancer Study GroupRectal Cancer

Start: 2003-11-30End: 2013-11-30Target: 102Updated: 2010-04-15

The Randomised Study of Preoperative Radiotherapy With Consolidating Chemotherapy for Unresectable Rectal Cancer

Polish Colorectal Cancer Study GroupRectal Cancer

Start: 2008-11-30End: 2015-11-30Target: 540Updated: 2010-04-15

Intraoperative Radiotherapy in Newly Diagnosed Glioblastoma Multiforme

Active, not recruitingNCT02685605

Universitätsmedizin MannheimGlioblastoma

Start: 2016-12-09End: 2026-06-30Updated: 2025-10-14

Paclitaxel, Cisplatin,5-FU vs. Radiotherapy Plus Paclitaxel, Cisplatin as Preoperative Therapy for Locally Advanced ESC

Tianjin Medical University Cancer Institute and HospitalEsophageal Cancer Stage IIB, Esophageal Cancer Stage III

Start: 2018-02-01End: 2022-12-31Target: 420Updated: 2018-01-09

Non Inferiority Study of Preoperative Chemotherapy Without Pelvic Irradiation for Rectal Cancer

RecruitingNCT03875781

Assistance Publique - Hôpitaux de ParisAdvanced Cancer, Rectal Cancer

Start: 2019-06-05End: 2026-12-05Target: 540Updated: 2026-01-15

Chemotherapy Followed by Pelvic Reirradiation Versus Chemotherapy Alone as Pre-operative Treatment for Locally Recurrent Rectal Cancer

Active, not recruitingNCT03879109

University Hospital, BordeauxRectal Cancer

Start: 2019-07-08End: 2027-12-31Updated: 2024-08-14

Unknown Phase

Impact of [11C]-Methionine PET/MRI for Individual Tailoring Postoperative Radiochemotherapy for Glioblastoma Multiforme

CompletedNCT01873469

Technische Universität DresdenGlioblastoma Multiforme

Start: 2013-07-31End: 2018-10-31Updated: 2019-02-18

Positron Emission Tomography (PET) During Radio-chemotherapy to Treat Otorhinolaryngological Cancer

CompletedNCT02469922

Center Eugene MarquisLocally Advanced Malignant Neoplasm, Malignant Neoplasm of Head and Neck

Start: 2014-06-30End: 2021-01-29Updated: 2021-07-27

Psychometric Properties of the EORTC QLQ-LC29

CompletedNCT02745691

University Hospital RegensburgLung Cancer

Start: 2016-04-01End: 2018-09-26Updated: 2019-12-13

Do Markers of Systemic Inflammatory Response and Tumor Metabolism Indicate Radioresistance in Head and Neck Cancer?

Luzerner KantonsspitalHead and Neck Squamous Cell Carcinoma

Start: 2020-01-01End: 2025-12-31Target: 100Updated: 2023-10-10

Radical CystEctomy or RaDio-chEMotherapy as Preferred Treatment for invasivE blaDder Cancer

Not yet recruitingNCT07008833

Brazilian Clinical Research InstituteMuscle Invasive Bladder Cancer

Start: 2026-06-01End: 2032-02-01Target: 336Updated: 2026-02-12

Related Papers

Long-term outcomes of total neoadjuvant treatment (TNT) for locally advanced rectal cancer: Maria Sklodowska Curie National Cancer Research Institute (MSCNCRI) cohort from Polish-II study.

Journal of Clinical Oncology2025-01-27

Efficacy and Safety of Intraoperative Radiotherapy for High-Grade Gliomas: A Systematic Review and Meta-Analysis.

2024-01-154 citations

Panitumumab in combination with chemoradiotherapy for the treatment of locally-advanced anal canal carcinoma: Results of the FFCD 0904 phase II trial.

2023-06-123 citations

NIMG-74. RESPONSE ASSESSMENT AFTER DOSE-ESCALATED RADIOTHERAPY: IMAGING PROTOCOL OF A MULTICENTER PHASE III TRIAL ON INTRAOPERATIVE RADIOTHERAPY IN NEWLY DIAGNOSED GLIOBLASTOMA (INTRAGO-II;ARO2016-1;AG-NRO-03)

Neuro-Oncology2021-11-02

Psychosocial Burden and Quality of Life of Lung Cancer Patients: Results of the EORTC QLQ-C30/QLQ-LC29 Questionnaire and Hornheide Screening Instrument

Cancer Management and Research2021-08-0126 citations

A multicenter, randomized, phase III trial of short-term radiotherapy plus chemotherapy versus long-term chemoradiotherapy in locally advanced rectal cancer (STELLAR): The final reports.

Journal of Clinical Oncology2021-05-2039 citations

Clinical evidence for association of neoadjuvant chemotherapy or chemoradiotherapy with efficacy and safety in patients with resectable esophageal carcinoma (NewEC study).

2020-06-2718 citations

NORAD01-GRECCAR16 multicenter phase III non-inferiority randomized trial comparing preoperative modified FOLFIRINOX without irradiation to radiochemotherapy for resectable locally advanced rectal cancer (intergroup FRENCH-GRECCAR- PRODIGE trial)

BMC Cancer2020-05-2928 citations

Psychometric properties of the updated EORTC module for assessing quality of life in patients with lung cancer (QLQ-LC29): an international, observational field study.

2020-03-2335 citations

Long-course preoperative chemoradiation versus 5 × 5 Gy and consolidation chemotherapy for clinical T4 and fixed clinical T3 rectal cancer: long-term results of the randomized Polish II study.

2019-08-01199 citations

Cost-effectiveness analysis of long-course oxaliplatin and bolus of fluorouracil based preoperative chemoradiotherapy vs. 5x5Gy radiation plus FOLFOX4 for locally advanced resectable rectal cancer.

2019-06-2415 citations

Anti-epidermal growth factor receptor therapy in combination with chemoradiotherapy for the treatment of locally advanced anal canal carcinoma: Results of a phase II study with panitumumab (FFCD 0904).

Journal of Clinical Oncology2019-05-202 citations

Intraoperative Radiotherapy in Newly Diagnosed Glioblastoma (INTRAGO): An Open-Label, Dose-Escalation Phase I/II Trial.

2019-01-0143 citations

NIMG-56. CHARACTERISTIC RESPONSE PATTERNS IN PATIENTS WITH NEWLY DIAGNOSED GLIOBLASTOMA AFTER TREATMENT WITH HIGH SINGLE DOSES OF RADIOTHERAPY

Neuro-Oncology2017-11-01

Effect of sex on treatment outcomes in rectal cancer patients after neoadjuvant radiotherapy or chemoradiation: A combined analysis of Polish-1 and Polish-2 studies.

Journal of Clinical Oncology2017-02-01

RTHP-05. INTRAOPERATIVE RADIOTHERAPY (IORT) USING LOW-ENERGY X-RAYS IN A COHORT OF PREDOMINANTLY INCOMPLETELY RESECTED NEWLY DIAGNOSED GLIOBLASTOMA MULTIFORME (INTRAGO TRIAL)

Neuro-Oncology2016-11-011 citations

Effects of neoadjuvant chemo or chemoradiotherapy for oesophageal cancer on perioperative haemodynamics

European Journal of Anaesthesiology2016-06-024 citations

Long-course oxaliplatin-based preoperative chemoradiation versus 5 × 5 Gy and consolidation chemotherapy for cT4 or fixed cT3 rectal cancer: results of a randomized phase III study.

2016-02-15295 citations

Neoadjuvant chemoradiation for fixed cT3 or cT4 rectal cancer: Results of a Polish II multicentre phase III study.

Journal of Clinical Oncology2016-02-0110 citations

A randomized clinical trial of neoadjuvant chemotherapy versus neoadjuvant chemoradiotherapy for cancer of the oesophagus or gastro-oesophageal junction.

2016-01-17283 citations

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