PREVYMIS 240 mg film-coated tablets
Sponsors
Allogene Therapeutics Inc., Fundacion Para La Investigacion Biomedica De Cordoba, Assistance Publique Hopitaux De Paris, Grupo Español de Trasplantes Hematopoyéticos y Terapia Celular, University Medical Center Ljubljana
Conditions
CMV infection in heart transplant recipientsCytoMegaloVirus infectionsCytomegalovirus infection in allogeneic stem cell transplant recipientsDiseases [C] - Virus Diseases [C02]Kidney transplantLarge B-Cell Lymphoma (LBCL)lung transplant patients (D+/R-)
Phase 2
A Single-Arm, Open-Label, Phase 1/2 Study Evaluating the Safety, Efficacy, and Cellular Kinetics/Pharmacodynamics of ALLO-501A, an Anti-CD19 Allogeneic CAR T Cell Therapy, and ALLO-647, an Anti-CD52 Monoclonal Antibody, in Subjects with Relapsed/Refractory Large B Cell Lymphoma (LBCL).
CompletedCTIS2022-501927-25-00
Start: 2023-09-29End: 2024-01-12Target: 35Updated: 2024-01-15
A Randomized, Open-Label, Phase 2 Study Evaluating Lymphodepletion With Fludarabine, Cyclophosphamide, And ALLO-647, Vs. Fludarabine And Cyclophosphamide Alone, In Subjects With Relapsed/Refractory Large B-Cell Lymphoma (LBCL) Receiving ALLO-501A Allogeneic CAR T Cell Therapy
CompletedCTIS2023-503830-27-00
Start: 2023-10-17End: 2024-10-28Target: 35Updated: 2024-01-29
Prospective study to evaluate the efficacy of letermovir prophylaxis for the prevention of CMV infection in lung transplant recipients compared to a retrospective cohort treated with standard valganciclovir prophylaxis for 12 months (LETERCOR Study)
RecruitingCTIS2023-504384-16-00
Start: 2023-12-18Target: 70Updated: 2025-12-17
Cytomegalovirus Prophylaxis with Letermovir in Heart Transplant Recipients: A Non-randomized Cohort Pilot Study
Not yet recruitingCTIS2024-517354-98-00
Target: 90Updated: 2024-09-17
Letermovir (LMV) prophylaxis in CMV-seronegative Allogeneic Stem Cell Transplant Recipients with CMV seropositive donors: an exploratory study from Spanish GETH/TC Centers
Not yet recruitingCTIS2024-516011-24-01
Target: 80Updated: 2025-02-24
Phase 3
LUCY-1 - Letermovir/valganciclovir combination versus valganciclovir monotherapy for treatment of cytomegalovirus (CMV) infections in kidney transplant recipients
RecruitingCTIS2023-506216-40-00
Start: 2024-08-14Target: 80Updated: 2025-07-16
CYMEVALIII - Prenatal treatment of congenital cytomegalovirus infection with letermovir randomized against valaciclovir (CYMEVAL) III
Not yet recruitingCTIS2024-512869-14-00
Target: 46Updated: 2024-07-22