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Cytomegalovirus Prophylaxis with Letermovir in Heart Transplant Recipients: A Non-randomized Cohort Pilot Study

Status
Not yet recruiting
Phases
Phase 2
Study type
Interventional
Source
EU CTIS
Registry ID
CTIS2024-517354-98-00
Acronym
V1.7
Enrollment
90
Registered
2024-09-17
Start date
Unknown
Completion date
Unknown
Last updated
2024-09-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

CMV infection in heart transplant recipients

Brief summary

The rate of early CMV infections/disease during virostatic prophylaxis.

Detailed description

•The rate of leukopenia during virostatic prophylaxis, •The rate of neutropenia during virostatic prophylaxis, •The rate of late CMV infections/disease between virostatic discontinuation and 6 months thereafter., •The time-course of the restitution of cell-mediated immunity during virostatic prophylaxis, •The rate of CMV resistance to virostatic therapy.

Interventions

Sponsors

University Medical Center Ljubljana
Lead SponsorOTHER

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Design outcomes

Primary

MeasureTime frame
The rate of early CMV infections/disease during virostatic prophylaxis.

Secondary

MeasureTime frame
•The rate of leukopenia during virostatic prophylaxis, •The rate of neutropenia during virostatic prophylaxis, •The rate of late CMV infections/disease between virostatic discontinuation and 6 months thereafter., •The time-course of the restitution of cell-mediated immunity during virostatic prophylaxis, •The rate of CMV resistance to virostatic therapy.

Countries

Slovenia

Outcome results

None listed

Source: EU CTIS · Data processed: Feb 4, 2026