N Acetylcysteine

DRUG13 trials

Sponsors

Shaare Zedek Medical Center, National Research Institute of Tuberculosis and Lung Disease, Iran, University of Iowa, Sunnybrook Health Sciences Centre, Hospital San Juan de Dios, Santiago

Conditions

Acute Renal Failure Contrast NephropathyCisplatin Adverse ReactionDiabetes Mellitus, Type 2Diabetic Kidney DiseaseDiabetic NephropathiesDigestive System Surgery AnaesthesiaDrug-Induced NephropathyEthanol Intoxication

Phase 1

Nutrition, Neuromuscular Electrical Stimulation (NMES) and Secondary Progressive Multiple Sclerosis (SPMS)

CompletedNCT01381354

University of IowaMultiple Sclerosis

Start: 2010-10-31End: 2016-05-31Updated: 2018-06-26

Phase 2

Memory and Antioxidants in Vascular Impairment Trial

CompletedNCT03306979

Sunnybrook Health Sciences CentreVascular Cognitive Impairment no Dementia

Start: 2018-04-30End: 2023-09-27Updated: 2025-03-26

Effect of N-acetylcysteine to reduce occurrence of adverse drug reactions in patients receiving multi drug resistant tuberculosis in Tanzania

Active, not recruitingPACTR202007736854169

Stellah MpagamaTuberculosis

Start: 2020-06-30Target: 60Updated: 2026-01-27

Possible Ameliorating Effect of N- Acetylcysteine (NAC) on Type-II Diabetes Induced Nephropathy

Al-Azhar UniversityDiabetes Mellitus, Type 2, Diabetic Kidney Disease, Diabetic Nephropathies

Start: 2019-10-01End: 2020-12-01Updated: 2020-08-28

N-acetylcysteine for root canal treatment of necrotic teeth with apical periodontitis.

Active, not recruitingPACTR202511513893768

Mai HusseinOral Health

Start: 2025-10-30Target: 40Updated: 2026-01-27

Unknown Phase

Prevention of Contrast Nephropathy by Sodium Bicarbonate Versus Sodium Chloride and N-acetylcysteine

CompletedNCT00353340

Shaare Zedek Medical CenterAcute Renal Failure Contrast Nephropathy

Start: 2005-01-31End: 2009-05-31Target: 250Updated: 2010-02-25

Investigation of the Effect of N Acetylcysteine Against Anti-Tuberculosis Drugs Induced Liver Toxicity

CompletedNCT00564642

National Research Institute of Tuberculosis and Lung Disease, IranHepatitis, Tuberculosis

Start: 2007-11-30End: 2009-04-30Updated: 2009-04-22

Protective Role of N-acetylcisteine From Cisplatin-induced Ototoxicity in Patients With Head and Neck Cancer

CompletedNCT03400709

Hospital San Juan de Dios, SantiagoCisplatin Adverse Reaction, Hearing Loss Ototoxic

Start: 2015-11-30End: 2017-11-30Updated: 2018-01-17

Safety And Efficacy Of Adding Intravenous N-Acetyl Cysteine To Parenteral L-Alanyl L-Glutamine In Hospitalized Patients Undergoing Colon Surgeries

Active, not recruitingPACTR201807118984852

ain shams universtyDigestive System Surgery Anaesthesia

Start: 2015-07-30Target: 63Updated: 2026-01-27

N-acetylcysteine Reduces Acetaldehyde Levels in Binge Alcohol Drinking

CompletedNCT05911282

University Medical Centre LjubljanaEthanol Intoxication

Start: 2021-06-01End: 2021-06-30Updated: 2023-06-22

Comparison of Dexamethasone and N Acetylcysteine (NAC) Versus N Acetylcysteine (NAC) Alone in the Prevention of Post Embolization Syndrome in Patients With Hepatocellular Carcinoma Following Transarterial Chemoembolization.

Institute of Liver and Biliary Sciences, IndiaHepatocellular Carcinoma

Start: 2023-09-15End: 2024-07-31Target: 150Updated: 2023-09-15

Drug Nephrotoxicity Amelioration by N-acetylcysteine

CompletedNCT06122311

Helwan UniversityDrug-Induced Nephropathy

Start: 2023-08-25End: 2024-06-10Updated: 2024-07-05

Effect Of N-Acetylcysteine On Neonatal Outcomes Of Perinatal Asphyxia; A Multicentre, Double-Blind Randomised Control Trial

Active, not recruitingPACTR202409657658949

Dr. Victor Ayodeji AyeniPaediatrics

Start: 2024-10-01Target: 66Updated: 2026-01-27

Related Papers

Heterogeneity in response to N‐acetylcysteine in vascular mild cognitive impairment

Alzheimer s & Dementia2025-12-01

Efficacy, Safety, and Cost-Effectiveness of N-Acetylcysteine in Preventing Amphotericin B Nephrotoxicity in Egyptian Patients with Hematological Malignancies: A Randomized Controlled Trial

Hospital Pharmacy2025-05-06

Protocol for a feasibility randomized controlled trial to evaluate the efficacy, safety and tolerability of N-acetylcysteine in reducing adverse drug reactions among adults treated for multidrug-resistant tuberculosis in Tanzania.

2023-04-012 citations