Melatonin,Placebo

10 trials

Sponsors

Faculty of Medicine, Khonkaen University, Faculty of Medicine, Siriraj Routine to research fund, Cardiac Electrophysiology Research and Training Center, Ratchadapiseksompotch Research Fund

Conditions

Endometrial cancer Melatonin Endometrial cancer Ki-67 Proliferative marker Randomized double blind placebo-control trialLower urinary tract symptoms in male patients with Nocturia Nocturia Prostatic Hyperplasia Melatonin Adrenergic alpha-Antagonists Lower Urinary Tract Symptoms Sleep Disorders Quality of LifeMajor depressive disorder cognitive function melatomin major depressive disorderPatient with schizophrenia. Schizophrenia Melatonin Weight gainPatients undergoing PCI with chronic kidney disease stage 3-5 (non-dialysis) with estimated glomerular filtration rate (eGFR) below than 60 mL/min/1.73 m2 measured by CKD-EPI method Contrast-induced acute kidney injury, Oxidative stress, Mitochondria, Prevention, MelatoninPlaque psoriasisPrimary outcomes: Can melatonin reduce symptoms in patients with irritable bowel syndrome better than placebo, as assessed by at least a 30% reduction in the average score of the most severe pain within 24 hours over 7 days, together with improved bowel movements according to FDA criteria? Secondary outcomes: Can melatonin improve the quality of life in patients with irritable bowel syndrome, as assessed by changes in the SF-36 (The Short Form Health Survey-36) and HADS (Hospital Anxiety and Dephealthy melatonin saliva cortisol amylase

Early Phase 1

The effect of melatonin in the improvement of the symptoms in irritable bowel syndrome patients with sleep disturbance

Active, not recruitingTCTR20210218002

Ratchadapiseksompotch Research Fundsymptoms of irritable bowel syndrome IBS symptom irritable bowel syndrome melatonin

Start: 2021-04-01Target: 28Updated: 2026-08-03

Phase 2

Protective effects of melatonin on kidney function against contrast media-induced kidney damage in patients with chronic kidney disease: A prospective, randomized, double-blinded, placebo-controlled trial

Active, not recruitingTCTR20210123004

Cardiac Electrophysiology Research and Training CenterPatients undergoing PCI with chronic kidney disease stage 3-5 (non-dialysis) with estimated glomerular filtration rate (eGFR) below than 60 mL/min/1.73 m2 measured by CKD-EPI method Contrast-induced acute kidney injury, Oxidative stress, Mitochondria, Prevention, Melatonin

Start: 2021-01-11Target: 40Updated: 2026-08-03

The effect of melatonin in the improvement of the symptoms in irritable bowel syndrome patients: A Randomized double-blind controlled trial

RecruitingTCTR20250916001

Department of Gastroenterology and Hepatology, Faculty of Medicine, Chulalongkorn UniversityPrimary outcomes: Can melatonin reduce symptoms in patients with irritable bowel syndrome better than placebo, as assessed by at least a 30% reduction in the average score of the most severe pain within 24 hours over 7 days, together with improved bowel movements according to FDA criteria? Secondary outcomes: Can melatonin improve the quality of life in patients with irritable bowel syndrome, as assessed by changes in the SF-36 (The Short Form Health Survey-36) and HADS (Hospital Anxiety and Dep

Start: 2025-06-10Target: 40Updated: 2026-08-03

Effect of melatonin for decreasing proliferative marker among women with endometrial cancer : A randomized double blind placebo-controlled trial

Active, not recruitingTCTR20260113003

Hospital research Fund, rajavithi hospitalEndometrial cancer Melatonin Endometrial cancer Ki-67 Proliferative marker Randomized double blind placebo-control trial

Start: 2026-01-16Target: 40Updated: 2026-08-03

Phase 3

Efficacy of melatonin to increase cognitive function in depressed patients(Pilot study)

Active, not recruitingTCTR20161219004

Faculty of MedicineMajor depressive disorder cognitive function melatomin major depressive disorder

Start: 2016-04-04Updated: 2026-08-03

Efficacy of Melatonin Treatment of Nocturia : a randomized controlled study

Active, not recruitingTCTR20200317007

Siriraj Routine to research fundside effect side effect

Start: 2020-03-05Target: 60Updated: 2026-08-03

The Effect of Melatonin on Reducing Nocturia in Males with Benign Prostatic enlargement

RecruitingTCTR20250907004

Phramongkutklao HospitalLower urinary tract symptoms in male patients with Nocturia Nocturia Prostatic Hyperplasia Melatonin Adrenergic alpha-Antagonists Lower Urinary Tract Symptoms Sleep Disorders Quality of Life

Start: 2025-10-01Target: 96Updated: 2026-08-03

ROLE OF MELATONIN AS AN ADJUNCTIVE TREATMENT IN PSORIASIS: A RANDOMIZED CONTROLLED TRIAL

RecruitingTCTR20251231009

NonePlaque psoriasis

Start: 2025-12-01Target: 20Updated: 2026-08-03

Phase 4

Efficacy of melatonin reducing weight gain in patients with schizophrenia using second generation antipsychotic drugs

RecruitingTCTR20160907002

Faculty of Medicine, Khonkaen UniversityPatient with schizophrenia. Schizophrenia Melatonin Weight gain

Start: 2016-08-06Target: 50Updated: 2026-08-03

Effects of melatonin on salivary stress markers

RecruitingTCTR20220310009

mahidol universityhealthy melatonin saliva cortisol amylase

Start: 2022-03-10Target: 65Updated: 2026-08-03

Related Papers

Protective Effects of Melatonin on Kidney Function Against Contrast Media‐Induced Kidney Damage in Patients With Chronic Kidney Disease: A Prospective, Randomized, Double‐Blinded, Placebo‐Controlled Trial

Journal of Pineal Research2025-01-017 citations