Low-Carbohydrate Diet

BEHAVIORAL20 trials

Sponsors

Temple University, Albert Einstein College of Medicine, University of Texas Southwestern Medical Center, Vårdcentralen Lyckorna, Stanford University

Conditions

AmputationDiabetesDiet ModificationDietary Carbohydrate Restriction, Energy DeficitEndocrine System DiseasesGlucose IntoleranceGlucose Metabolism Disorders (Including Diabetes Mellitus)Hyperglycemia

Phase 4

The Safety and Effectiveness of Low and High Carbohydrate Diets

CompletedNCT00079547

Temple UniversityObesity

Start: 2003-04-30End: 2008-03-31Updated: 2013-07-01

Unknown Phase

Diabetes Dietary Study- Low Carbohydrate and Low-Fat Diets in Type 2 Diabetes

CompletedNCT00795691

Albert Einstein College of MedicineType 2 Diabetes

Start: 2004-05-31End: 2008-12-31Updated: 2019-07-12

Effect of Dietary Macronutrient Composition

CompletedNCT01371396

University of Texas Southwestern Medical CenterMetabolic Syndrome, Non-alcoholic Fatty Liver Disease, Obesity

Start: 2007-09-01End: 2013-12-31Updated: 2019-02-06

A Randomized Cross-over Trial of the Postprandial Effects of Three Different Diets in Patients With Type 2 Diabetes

CompletedNCT01522157

Vårdcentralen LyckornaType 2 Diabetes Mellitus

Start: 2012-01-31End: 2012-07-31Updated: 2013-12-02

Weight Loss Diet Study: Low Carb vs Low Fat

CompletedNCT01661426

Stanford UniversityInsulin Resistance, Obesity

Start: 2012-04-30End: 2013-03-31Updated: 2023-02-22

DIETFITS Study (Diet Intervention Examining the Factors Interacting With Treatment Success

CompletedNCT01826591

Stanford UniversityInsulin Resistance, Obesity

Start: 2013-01-31End: 2016-05-31Updated: 2023-02-21

Bitter Taste and Weight Loss in Women

CompletedNCT01856660

Rutgers UniversityObesity, Weight Loss

Start: 2012-09-30End: 2016-08-31Updated: 2021-08-24

Lifestyle Control of Postprandial Hyperglycemia

CompletedNCT02683135

University of British ColumbiaType 2 Diabetes

Start: 2015-11-30End: 2017-06-01Updated: 2017-08-03

Effects of Acute Dietary Changes on Estimates of Body Composition

CompletedNCT02888405

Baylor UniversityOverweight

Start: 2015-11-30End: 2016-02-29Updated: 2016-09-05

Effect of a Modified Ketogenic-Mediterranean Diet on Alzheimer's Disease

CompletedNCT02984540

Wake Forest University Health SciencesInsulin Resistance, Mild Cognitive Impairment

Start: 2015-02-28End: 2017-04-03Updated: 2025-07-28

Low-Carbohydrate Dietary Pattern on Glycemic Outcomes Trial

CompletedNCT03675360

Tulane University School of Public Health and Tropical MedicineDiabetes, Diet Modification, Endocrine System Diseases +5

Start: 2018-09-25End: 2021-06-21Updated: 2023-03-01

Testing the Effect of Multiple Weight Management Modalities for Chronic Disease Risk Reduction in a Clinical Setting

CompletedNCT03998878

University of ArizonaObesity

Start: 2019-08-08End: 2021-12-16Updated: 2021-12-17

Investigating Racial Differences in Diet Benefits for Knee Osteoarthritis

CompletedNCT04343716

University of Alabama at BirminghamKnee Osteoarthritis

Start: 2020-10-01End: 2023-09-18Updated: 2025-01-09

Efficacy and Safety of Low-Carbohydrate Diet Combined With Probiotics for Weight Loss in Male Obese Patients.

CompletedNCT04886778

Start: 2021-06-01End: 2022-03-01Updated: 2024-03-13

Low-carbohydrate Diet in Children with Type 1 Diabetes

Active, not recruitingNCT05078658

University Hospital, MotolType1diabetes

Start: 2021-09-22End: 2025-12-31Updated: 2024-12-09

Low-Carb Versus Mediterranean Diet in PCOS

Federal State Budgetary Institution, V. A. Almazov Federal North-West Medical Research Centre, of the Ministry of HealthPolycystic Ovary Syndrome (PCOS)

Start: 2022-03-30End: 2024-06-30Target: 130Updated: 2022-04-01

The Pain in Amputees Reduced by Administration of Diet Examination

CompletedNCT05460845

University of Alabama at BirminghamAmputation, Phantom Limb Pain, Residual Limb Pain

Start: 2022-07-01End: 2023-08-28Updated: 2023-08-30

The Transform Type 2 Diabetes Study

Oviva UK LtdType2diabetes

Start: 2022-01-07End: 2024-07-30Target: 120Updated: 2022-12-13

Diet Order Effects of Low Fat vs. Low Carb Diets on Body Fat Change

RecruitingNCT06325722

National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)Obesity, Overweight

Start: 2024-08-28End: 2026-07-31Target: 42Updated: 2026-03-31

Metabolic Flexibility and Ketone Production During Energy Deficit

CompletedNCT07429058

Technical University of MunichDietary Carbohydrate Restriction, Energy Deficit

Start: 2023-11-24End: 2024-04-26Updated: 2026-02-24

Related Papers

Body Composition Changes after 6- and 12-months of Dietary Weight Loss: Insights from the DIETFITS Trial

Journal of the Endocrine Society2026-01-18

SAT-707 Lean Mass Loss after Dietary Weight Loss: A Secondary Analysis of the DIETFITS Randomized Clinical Trial

Journal of the Endocrine Society2025-10-01

Weight loss in MASLD restores the balance of liver fatty acid sources

Journal of Clinical Investigation2025-05-016 citations

Differential weight‐loss responses of <scp><i>APOA2</i></scp> genotype carriers to low‐carbohydrate and low‐fat diets: the <scp>DIETFITS</scp> trial

Obesity2025-05-012 citations

The effect of a low-carbohydrate diet on evoked pain and quality of life in Non-Hispanic black women with knee osteoarthritis: a pilot study.

2024-12-191 citations

Association of dietary adherence and dietary quality with weight loss success among those following low-carbohydrate and low-fat diets: a secondary analysis of the DIETFITS randomized clinical trial.

2023-11-045 citations

1128-P: Changes in Gut Bacteriome Composition on Low-Carbohydrate Diet in Children with Type 1 Diabetes

Diabetes2023-06-20

Evidence for the carbohydrate–insulin model in a reanalysis of the Diet Intervention Examining The Factors Interacting with Treatment Success (DIETFITS) trial

American Journal of Clinical Nutrition2023-01-059 citations

Development and evaluation of a novel dietary bisphenol A (BPA) exposure risk tool.

2022-12-065 citations

Effects of a Low-Carbohydrate Dietary Intervention on Hemoglobin A<sub>1c</sub>

JAMA Network Open2022-10-2646 citations

Changes in Adiposity and Cerebrospinal Fluid Biomarkers Following a Modified Mediterranean Ketogenic Diet in Older Adults at Risk for Alzheimer’s Disease

Frontiers in Neuroscience2022-06-0218 citations

Temporal changes in soluble angiotensin-converting enzyme 2 associated with metabolic health, body composition, and proteome dynamics during a weight loss diet intervention: a randomized trial with implications for the COVID-19 pandemic.

2021-11-016 citations

Low-carbohydrate dietary pattern on glycemic outcomes trial (ADEPT) among individuals with elevated hemoglobin A1c: study protocol for a randomized controlled trial

Trials2021-02-016 citations

Long-term dietary intervention reveals resilience of the gut microbiota despite changes in diet and weight

American Journal of Clinical Nutrition2020-02-25125 citations

To Text or Not to Text: Electronic Message Intervention to Improve Treatment Adherence Versus Matched Historical Controls.

2019-04-094 citations

Changes in blood lipid concentrations associated with changes in intake of dietary saturated fat in the context of a healthy low-carbohydrate weight-loss diet: a secondary analysis of the Diet Intervention Examining The Factors Interacting with Treatment Success (DIETFITS) trial.

2019-02-0124 citations

Effect of Low-Fat vs Low-Carbohydrate Diet on 12-Month Weight Loss in Overweight Adults and the Association With Genotype Pattern or Insulin Secretion

JAMA2018-02-20668 citations

Effect of a mobile app intervention on vegetable consumption in overweight adults: a randomized controlled trial.

2017-09-1553 citations

Iterative development of Vegethon: a theory-based mobile app intervention to increase vegetable consumption.

2016-08-0849 citations

Mobile Technology for Vegetable Consumption: A Randomized Controlled Pilot Study in Overweight Adults

JMIR mhealth and uhealth2016-05-1861 citations

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