Type 2 Diabetes Mellitus
Conditions
Keywords
Diet, Low-carbohydrate, Postprandial, Type 2 diabetes mellitus
Brief summary
The trial will study the acute metabolic effects of three different types of diet: low-fat diet, low-carbohydrate diet and Mediterranean diet. About 20 patients with diabetes mellitus type 2 will be recruited and each of them will be given each type of diet on three different days. Menus with the same energy content but with different content of fat, carbohydrate and protein are designed. Breakfast and lunch are served for the patients each day of testing. Laboratory samplings are performed six times during the day. The order of the dietary intervention is randomized for each patient. The investigators suppose to find different reaction in plasma glucose and lipids depending on the type of diet.
Interventions
DIETARY_SUPPLEMENTLow-fat Diet
Low-fat Diet is provided for a breakfast and a lunch.
DIETARY_SUPPLEMENTLow-carbohydrate Diet
Low-carbohydrate Diet is provided for a breakfast and a lunch.
DIETARY_SUPPLEMENTMediterranean Diet
Mediterranean Diet is provided for a breakfast and a lunch.
Sponsors
Vårdcentralen Lyckorna
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Diabetes mellitus type 2
Exclusion criteria
* Treatment with insulin or sulfonylurea
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| P-glucose | 6 months | mmol/l |
| P-Triglycerides | 6 months | mmol/l |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| P-Cholesterol | 6 months | mmol/l |
| P-LDL-Cholesterol | 6 months | mmol/l |
| P-HDL-Cholesterol | 6 months | mmol/l |
Countries
Sweden
Outcome results
None listed