Lactose monohydrate
Sponsors
University Medical Center Utrecht, Sling Therapeutics Inc., Hemato-Oncologie voor Volwassenen Nederland (Hovon) Stichting, Karolinska Institutet, Inventiva
Conditions
(Chronic) Peripheral (occlusive) arterial disease (PAD)Acute CMV HepatitisAcute EBV HepatitisAcute Hepatitis AAcute Hepatitis BAcute Hepatitis CAcute Hepatitis EAcute ischemic stroke
Phase 2
Randomized Placebo-controlled Trial Evaluating the Safety and Efficacy of Silymarin Treatment in Patients With Acute Viral Hepatitis
TerminatedNCT00755950
Start: 2008-10-31End: 2015-12-31Updated: 2021-04-23
A Multicenter, Extension Study to Evaluate the Efficacy, Safety, Pharmacokinetics, and Pharmacodynamics of Two Doses of Linsitinib in Subjects with Active, Moderate to Severe Thyroid Eye Disease (TED)
CompletedCTIS2022-502812-35-00
Start: 2023-10-26End: 2025-06-06Target: 6Updated: 2025-07-25
Add-on buprenorphine at analgesic doses for the treatment of severe suicidal ideas during a major depressive episode
RecruitingCTIS2024-512445-17-00
Start: 2021-07-01Target: 180Updated: 2025-09-24
A Phase 2b, Randomized, Double-Mask, Placebo-Controlled, Study to Evaluate the
Safety, Pharmacokinetics and Efficacy of Linsitinib in Subjects with Active, Moderate to Severe Thyroid Eye Disease (TED)
CompletedCTIS2024-514449-12-00
Start: 2022-11-04End: 2025-09-26Target: 18Updated: 2025-10-27
Hydroxychloroquine treatment for Recurrent Pregnancy Loss: a randomized double-blind placebo-controlled trial
RecruitingCTIS2024-515579-36-00
Start: 2017-04-12Target: 186Updated: 2025-12-02
Phase 3
Rhodiola Rosea Therapy of Major Depressive Disorder
CompletedNCT01098318
Start: 2010-06-30End: 2013-07-31Updated: 2018-02-22
Amantadine for COVID-19
NCT04894617
Start: 2021-06-01End: 2022-04-30Target: 226Updated: 2021-10-06
A phase 3, randomised, double-blind, placebo-controlled, parallel-arm efficacy trial of Imatinib in acute ischaemic stroke
SuspendedCTIS2023-506178-11-00
Start: 2025-11-11Target: 680Updated: 2023-11-07
PILOT STUDY OF THE EFFECT OF A SUBSTANCE P ANTAGONIST,
APREPITANT, ON THE SECRETION OF ALDOSTERONE IN PATIENTS WITH
OBSTRUCTIVE SLEEP APNEA AND ARTERIAL HYPERTENSION SYNDROME - (APHOS3)
Not yet recruitingCTIS2024-514837-39-00
Target: 24Updated: 2024-07-01
CLEAR-PATH A randomized placebo-controlled double-blind trial studying the effect of single antiplatelet therapy (clopidogrel) versus dual antiplatelet therapy (clopidogrel/acetylsalicylic acid) on the occurrence of atherothrombotic events following lower extremity peripheral transluminal angioplasty
Not yet recruitingCTIS2024-513363-15-01
Target: 1696Updated: 2025-08-14
A randomised, double-blind, placebo-controlled, multicentre, Phase 3 study evaluating efficacy and safety of lanifibranor followed by an active treatment extension in adult patient with non-cirrhotic non-alcoholic steatohepatitis (NASH) and fibrosis 2 (F2)/fibrosis 3 (F3) stage of liver fibrosis
Active, not recruitingCTIS2023-508248-23-00
Start: 2021-11-26Target: 236Updated: 2025-11-10
A MULTICENTER, PROSPECTIVE, RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED TRIAL OF SPIRONOLACTONE FOR THE TREATMENT OF ACTIVE RHEUMATOID ARTHRITIS (RA) - ALDORA
RecruitingCTIS2024-516884-10-00
Start: 2022-06-22Target: 153Updated: 2024-09-11
Evaluating oral peri-operative acetylsalicylic acid in subjects undergoing endovascular coiling-only of unruptured brain aneurysms (EVOLVE)
RecruitingCTIS2024-517674-23-00
Start: 2023-05-05Target: 200Updated: 2025-04-15
HOVON 150 AML: A phase 3, multicenter, double-blind, randomized, placebo-controlled study of ivosidenib or enasidenib in combination with induction therapy and consolidation therapy followed by maintenance therapy in patients with newly diagnosed acute myeloid leukemia or myelodysplastic syndrome with excess blasts-2, with an IDH1 or IDH2 mutation, respectively, eligible for intensive chemotherapy.
Active, not recruitingCTIS2022-502832-37-00
Start: 2019-03-01Target: 852Updated: 2025-07-02
Effectiveness of ambroxol in children and adults with Gaucher disease 3: n-of-1 series
Not yet recruitingCTIS2024-514012-28-00
Target: 4Updated: 2024-11-25
Melatonin for patients with chronic low back pain (MELBACK) - a randomized placebo-controlled trial
RecruitingCTIS2024-514769-20-00
Start: 2025-03-02Target: 240Updated: 2025-01-15
Duration of Dual Anti-Platelet Therapy in Chronic Limb Threatening Ischemia after Distal Revascularization: a randomized, double-blind trial
PALADIN [PeripherAL Arterial DIsease Network] -DAPTCLTI
Not yet recruitingCTIS2025-524297-42-00
Target: 614Updated: 2026-03-05
Phase 4
European Randomised Clinical Trial on mPOX Infection (EPOXI)
CompletedCTIS2022-501979-10-00
Start: 2024-08-08End: 2025-07-14Target: 335Updated: 2025-06-26
Simvastatin in the Prevention of Recurrent Pancreatitis, a Triple Blind, Randomized Controlled Trial.
Not yet recruitingCTIS2024-513188-17-03
Target: 144Updated: 2024-09-25