L-thyroxine

DRUG7 trials

Conditions

Bipolar DisorderCardiac FunctionCardiac Surgery Intensive Care TreatmentCardiac Surgery Requiring Cardiopulmonary BypassChildrenDelayed Recovery From AnaesthesiaEndocrine System DiseasesEuthyroid Sick Syndrome

Phase 2

Supraphysiological Doses of Levothyroxine as Adjunctive Therapy in Bipolar Depression

CompletedNCT01528839

Charite University, Berlin, GermanyBipolar Disorder

Start: 2004-03-31End: 2008-08-31Updated: 2012-02-08

Phase 3

L-Thyroxine Supplementation for Preterm Newborns Less Than 32 Weeks of Gestation With Hypothyroxinemia

CompletedNCT01306227

Centre Hospitalier Universitaire, AmiensHypothyroxinemia

Start: 2006-09-01End: 2017-12-31Updated: 2018-08-10

Role of Levothyroxine Supplementation in Delayed Recovery Following Cardiac Surgery

CompletedNCT06660823

Ain Shams UniversityCardiac Surgery Intensive Care Treatment, Cardiac Surgery Requiring Cardiopulmonary Bypass, Delayed Recovery From Anaesthesia +1

Start: 2024-11-30End: 2025-06-25Updated: 2025-08-17

Phase 4

Effect of L-Thyroxine on Lipid Profiles and Atherosclerosis in Subclinical Hypothyroidism

NCT01831869

Shandong Provincial HospitalEndocrine System Diseases, Hypothyroidism, Thyroid Diseases

Start: 2013-04-30End: 2022-04-30Target: 400Updated: 2018-09-12

Effects of L-thyroxine Replacement on Serum Lipid and Atherosclerosis in Hypothyroidism

NCT01848171

Shandong Provincial HospitalEndocrine System Diseases, Hypothyroidism, Thyroid Diseases

Start: 2013-07-31End: 2023-07-31Target: 700Updated: 2023-01-18

Unknown Phase

Metabolic Changes in Hypothyroid Patients

CompletedNCT00524238

University of AarhusHypothyroidism

Start: 2004-03-31End: 2006-08-31Updated: 2008-02-12

Levothyroxine Treatment on Cardiac Function in Children With Subclinical Hypothyroidism

RecruitingNCT07393165

Tanta UniversityCardiac Function, Children, Levothyroxine +1

Start: 2025-05-24End: 2026-05-01Target: 40Updated: 2026-02-06

Frontiers in Cellular and Infection Microbiology2020-09-1847 citations

Treatment of bipolar depression with supraphysiologic doses of levothyroxine: a randomized, placebo-controlled study of comorbid anxiety symptoms

International Journal of Bipolar Disorders2019-10-0418 citations

Benefits of Levothyroxine Replacement Therapy on Nonalcoholic Fatty Liver Disease in Subclinical Hypothyroidism Patients

International Journal of Endocrinology2017-01-0170 citations

Supraphysiologic Doses of Levothyroxine as Adjunctive Therapy in Bipolar Depression

The Journal of Clinical Psychiatry2013-11-2046 citations