isosorbide mononitrate

DRUG18 trials

Conditions

Anal FissureCerebral Small Vessel DiseasesCervical RipeningCirrhosisCognitive ImpairmentGastrointestinal HemorrhageHealthy SubjectsHeart Failure

Early Phase 1

Uterine Artery Doppler Changes After Vaginal Administration of Isosorbide Mononitrate In Patients With URPL

NCT05341856

Al-Azhar UniversityRecurrent Pregnancy Loss

Start: 2022-05-01End: 2022-09-30Target: 60Updated: 2022-04-22

Phase 1

PK, PD and Safety Comparative Trial of Isosorbide Mononitrate Gel in Healthy Participants and With Anal Fissure

WithdrawnNCT02667535

Biolab Sanus FarmaceuticaAnal Fissure

Start: 2017-07-31End: 2017-11-30Updated: 2017-07-17

Pharmacokinetics Trial of Isosorbide Mononitrate 0.5% Gel for Intra Anal Application in Healthy Subjects

WithdrawnNCT04729088

Biolab Sanus FarmaceuticaHealthy Subjects, Pharmacokinetics

Start: 2020-12-20End: 2020-12-20Updated: 2021-02-01

Vasodilator Therapy With Isosorbide Mononitrate or Diltiazem to Reduce Vasotoxicity in Patients With Gastrointestinal Cancer Receiving Fluoropyrimidine Therapy

Not yet recruitingNCT07456852

Mayo ClinicMalignant Digestive System Neoplasm

Start: 2026-03-31End: 2030-03-31Target: 60Updated: 2026-03-09

Phase 2

Nitrate's Effect on Activity Tolerance in Heart Failure With Preserved Ejection Fraction

CompletedNCT02053493

Adrian HernandezHeart Failure

Start: 2014-04-30End: 2015-03-31Updated: 2016-11-28

Lacunar Intervention Trial 1 (LACI-1)

CompletedNCT02481323

University of EdinburghCerebral Small Vessel Diseases, Cognitive Impairment, Stroke

Start: 2016-03-31End: 2017-11-30Updated: 2018-01-19

Termination Of Anembryonic Pregnancy

WithdrawnNCT02573051

Assiut UniversityMissed Abortion

Start: 2015-06-30End: 2015-12-01Updated: 2024-07-31

Nitric Oxide Donors for Treatment of Isolated Oligohydramnios

CompletedNCT02712125

Benha UniversityIsolated (Idiopathic) Oligohydramnios

Start: 2013-08-31End: 2015-08-31Updated: 2016-03-18

Using Isosorbide Mononitrate in Reducing Time in Induction of Labor in Post Date Women

NCT03854383

Abdelrahman Ali Fadel Youssef MohamedInduction of Labor

Start: 2019-03-03End: 2019-07-01Target: 100Updated: 2019-03-12

Isosorbide Mononitrate For Anti-Vascular Endothelial Growth Factor (VEGF) Induced Kidney Injury

TerminatedNCT04051957

The University of Texas Health Science Center, HoustonHypertension, Kidney Injury, Proteinuria

Start: 2019-09-26End: 2021-02-12Updated: 2022-08-03

Phase 3

Nitric Oxide Donor Isosorbide Mono Nitrate for Induction of Labor With Pre-labor Rupture of Membranes

CompletedNCT03665779

ahmed nagy shaker ramadanInduction of Labor Affected Fetus / Newborn, Rupture of Membranes Prior to Onset of Labor

Start: 2018-08-01End: 2019-05-01Updated: 2020-06-23

the Effect of Isosorbide Mononitrate in Reducing Pain During Cooper Intrauterine Device Insertion

CompletedNCT04312048

Cairo UniversityIUD Insertion Pain

Start: 2020-04-15End: 2020-11-30Updated: 2021-01-20

Isosorbide Mononitrate and Butylphthalide to Reduce the Risk of Disability in Patients With Acute Lacunar Stroke (IMPACT)

Not yet recruitingNCT07252544

Beijing Tiantan HospitalCerebral Small Vessel Diseases, Stroke, Acute Ischemic, Stroke, Lacunar

Start: 2025-12-01End: 2028-02-29Target: 3156Updated: 2025-11-26

Phase 4

Secondary Prophylaxis After Variceal Bleeding in Non-Responders

CompletedNCT00450164

Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant PauCirrhosis, Gastrointestinal Hemorrhage, Portal Hypertension

Start: 2000-11-30End: 2004-06-30Target: 50Updated: 2007-03-21

Misoprosotol and Isosorbide Mononitrate for Induction of Second Trimester Abortion

CompletedNCT03407521

Ain Shams UniversitySecond Trimester Abortion

Start: 2017-04-12End: 2017-12-15Updated: 2018-02-28

Nitric Oxide Donor Isosorbide Mono Nitrate for Cervical Ripening in Induction of Labor

CompletedNCT03544606

ahmed nagy shaker ramadanInduction of Labor Affected Fetus / Newborn

Start: 2023-12-01End: 2024-06-30Updated: 2024-08-22

Unknown Phase

Pain Relief During IUD Insertion in Women Delivered Only by Elective Cesarean Section

NCT03587077

Assiut UniversityIUD Insertion Complication

Start: 2018-09-30End: 2019-05-31Target: 113Updated: 2018-07-16

Cervical Ripening With Misoprostol vs Isosorbide Mononitrate ; A Parallel -Arm Randomized Controlled Trial

Active, not recruitingNCT07121634

Raid M. Al-AniCervical Ripening

Start: 2024-01-01End: 2026-08-31Updated: 2025-08-13

Gynecology and Obstetrics Clinical Medicine2025-01-01

Interleukin-6 in Patients With Heart Failure and Preserved Ejection Fraction.

2023-08-0971 citations

Effects of Cilostazol and Isosorbide Mononitrate on Cerebral Hemodynamics in the LACI-1 Randomized Controlled Trial

Stroke2021-12-0121 citations

RETRACTED: Isosorbide mononitrate for cervical ripening in induction of labor for pregnant women with PROM at or post term

International Journal of Gynecology & Obstetrics2021-01-183 citations

Quality of Life in Heart Failure with Preserved Ejection Fraction: Importance of Obesity, Functional Capacity, and Physical Inactivity

European Journal of Heart Failure2020-03-09226 citations

Tolerability, safety and intermediary pharmacological effects of cilostazol and isosorbide mononitrate, alone and combined, in patients with lacunar ischaemic stroke: The LACunar Intervention-1 (LACI-1) trial, a randomised clinical trial.

2019-04-2443 citations

Accelerometer-Measured Daily Activity in Heart Failure With Preserved Ejection Fraction

Circulation Heart Failure2017-06-0160 citations

Isosorbide Mononitrate in Heart Failure with Preserved Ejection Fraction

New England Journal of Medicine2015-11-08528 citations