GADOTERIC ACID
Sponsors
Bayer AG, Novo Nordisk A/S, Eli Lilly & Co., Hospices Civils De Lyon, Assistance Publique Hopitaux De Paris
Conditions
Adverse Reaction to DrugAllergic Reaction to Contrast MediaArterial Occlusive DiseaseContrast enhancement in magnetic resonance imaging for assessment of central nervous system pathologyContrast enhancement in magnetic resonance imaging for assessment of non-central nervous system pathologyDiabetic Kidney DiseaseHeart Failure With Preserved Ejection Fraction (HFPEF)Huntington's disease
Phase 1
(ASK-HD-01-CS-101) An Open-Label Phase I/II Dose Finding Study to Evaluate the Safety, Tolerability, and Preliminary Efficacy of Striatal Administration of AB-1001 in Adult Subjects with Early Manifest Huntington’s Disease (HD)
Active, not recruitingCTIS2024-510895-18-00
Start: 2024-11-07Target: 18Updated: 2025-11-24
[18F]-Fludarabine PET/MR Imaging for the Assessment of Newly-diagnosed Primary Central Nervous System (CNS) Lymphoma : a Pilot PET-MRI Study
CompletedCTIS2024-512758-62-00
Start: 2023-12-18End: 2024-12-05Target: 16Updated: 2024-11-08
Phase 2
PLAQUE AND BRAIN INFLAMMATION IN SYMPTOMATIC CAROTID STENOSIS: ROLE OF THE FICOLIN-2
STATEMENT
Active, not recruitingCTIS2023-504573-20-00
Start: 2023-10-09Target: 20Updated: 2026-01-21
QUANTITATIVE RENAL HYPERPOLARIZED [1-13C]PYRUVATE PERFUSION AND METABOLIC IMAGING IN DIABETIC KIDNEY DISEASE
RecruitingCTIS2023-508824-36-00
Start: 2024-09-24Target: 27Updated: 2025-02-12
An Adaptive Phase 2a/2b, Randomized, Double-Blind, Parallel-Group Study to Investigate the Safety and Efficacy of LY3541860 Compared to Placebo in Slowing the Occurrence of New T1 Gadolinium-Enhancing Lesions in Adult Participants with Relapsing Multiple Sclerosis
CompletedCTIS2023-503289-22-00
Start: 2024-07-05End: 2025-12-15Target: 57Updated: 2026-01-09
Open-label extension study of long-term safety and efficacy of NNC6019-0001 in participants with transthyretin amyloid cardiomyopathy (ATTR CM)
Active, not recruitingCTIS2022-502605-15-00
Start: 2024-09-16Target: 58Updated: 2025-11-24
Mangafodipir - an Intracellular Contrast Agent for Magnetic Resonance Imaging (MRI): Measuring Manganese Uptake Rate in Heart Failure Patients With Preserved Ejection Fraction (HFpEF) Patients.
CompletedNCT06731738
Start: 2024-11-22End: 2025-11-29Updated: 2026-01-08
Phase 3
(21197) A multicenter, randomized, prospective double-blind, cross over Phase 3 study to evaluate the efficacy and safety of 0.04 mmol Gd/kg body weight of gadoquatrane for MRI in adults with known or suspected pathology of any body region (except CNS), compared to 0.1 mmol Gd/kg approved macrocyclic gadolinium-based contrast agents (GBCAs)
CompletedCTIS2022-501885-24-00
Start: 2023-09-20End: 2024-12-20Target: 265Updated: 2024-05-21
(21181) A multicenter, randomized, prospective double-blind, cross over Phase 3 study to evaluate the efficacy and safety of 0.04 mmol Gd/kg body weight of gadoquatrane for MRI in adults with known or suspected pathology of the central nervous system (CNS), compared to 0.1 mmol Gd/kg approved macrocyclic gadolinium-based contrast agents (GBCAs)
CompletedCTIS2022-501884-41-00
Start: 2023-09-29End: 2024-12-17Target: 186Updated: 2024-05-21
DASSOH - Systematic use of DDAVP to prevent serum sodium overcorrection in severe hyponatremia : a multicenter open-label randomized controlled trial
RecruitingCTIS2023-507254-32-00
Start: 2024-12-17Target: 260Updated: 2025-10-24
Phase 4
A Clinical Study of Gadoteric Acid in Non-Coronary Magnetic Resonance (MR) Angiography
CompletedNCT00447889
Start: 2006-03-31End: 2007-11-30Updated: 2008-11-26
Evaluation of Inner Ear and Brain Structures With Contrast-enhanced MRI in Healthy Subjects (HYDROPS)
TerminatedNCT02529475
Start: 2016-02-01End: 2020-09-30Updated: 2020-11-18
Prospective evaluation of potential effects of repeated gadolinium-based contrast agent (GBCA) administrations of the same GBCA on motor and cognitive functions in neurologically normal adults in comparison to a non-GBCA exposed control group—ODYSSEY
Not yet recruitingCTIS2024-515462-14-00
Target: 717Updated: 2025-01-10