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GADOTERIC ACID

DRUG15 trials

Sponsors

Bayer AG, Novo Nordisk A/S, Eli Lilly & Co., Hospices Civils De Lyon, Assistance Publique Hopitaux De Paris

Conditions

Adverse Reaction to DrugAllergic Reaction to Contrast MediaArterial Occlusive DiseaseContrast enhancement in magnetic resonance imaging for assessment of central nervous system pathologyContrast enhancement in magnetic resonance imaging for assessment of non-central nervous system pathologyDiabetic Kidney DiseaseHeart Failure With Preserved Ejection Fraction (HFPEF)Hereditary Spastic Paraplegia Type 50 (SPG50)

Phase 1

Phase 2

PLAQUE AND BRAIN INFLAMMATION IN SYMPTOMATIC CAROTID STENOSIS: ROLE OF THE FICOLIN-2 STATEMENT
Active, not recruitingCTIS2023-504573-20-00
Hospices Civils De Lyonstroke or transient ischemic attack
Start: 2023-10-09Target: 20Updated: 2026-01-21
QUANTITATIVE RENAL HYPERPOLARIZED [1-13C]PYRUVATE PERFUSION AND METABOLIC IMAGING IN DIABETIC KIDNEY DISEASE
RecruitingCTIS2023-508824-36-00
Aarhus UniversitetDiabetic Kidney Disease
Start: 2024-09-24Target: 27Updated: 2025-02-12
An Adaptive Phase 2a/2b, Randomized, Double-Blind, Parallel-Group Study to Investigate the Safety and Efficacy of LY3541860 Compared to Placebo in Slowing the Occurrence of New T1 Gadolinium-Enhancing Lesions in Adult Participants with Relapsing Multiple Sclerosis
CompletedCTIS2023-503289-22-00
Eli Lilly & Co.Relapsing Multiple Sclerosis
Start: 2024-07-05End: 2025-12-15Target: 57Updated: 2026-01-09
Open-label extension study of long-term safety and efficacy of NNC6019-0001 in participants with transthyretin amyloid cardiomyopathy (ATTR CM)
Active, not recruitingCTIS2022-502605-15-00
Novo Nordisk A/SParticipants with transthyretin amyloid cardiomyopathy (ATTR CM)
Start: 2024-09-16Target: 58Updated: 2025-11-24
Mangafodipir - an Intracellular Contrast Agent for Magnetic Resonance Imaging (MRI): Measuring Manganese Uptake Rate in Heart Failure Patients With Preserved Ejection Fraction (HFpEF) Patients.
CompletedNCT06731738
IC TARGETS ASHeart Failure With Preserved Ejection Fraction (HFPEF)
Start: 2024-11-22End: 2025-11-29Updated: 2026-01-08

Phase 3

(21197) A multicenter, randomized, prospective double-blind, cross over Phase 3 study to evaluate the efficacy and safety of 0.04 mmol Gd/kg body weight of gadoquatrane for MRI in adults with known or suspected pathology of any body region (except CNS), compared to 0.1 mmol Gd/kg approved macrocyclic gadolinium-based contrast agents (GBCAs)
CompletedCTIS2022-501885-24-00
Bayer AGContrast enhancement in magnetic resonance imaging for assessment of non-central nervous system pathology
Start: 2023-09-20End: 2024-12-20Target: 265Updated: 2024-05-21
(21181) A multicenter, randomized, prospective double-blind, cross over Phase 3 study to evaluate the efficacy and safety of 0.04 mmol Gd/kg body weight of gadoquatrane for MRI in adults with known or suspected pathology of the central nervous system (CNS), compared to 0.1 mmol Gd/kg approved macrocyclic gadolinium-based contrast agents (GBCAs)
CompletedCTIS2022-501884-41-00
Bayer AGContrast enhancement in magnetic resonance imaging for assessment of central nervous system pathology
Start: 2023-09-29End: 2024-12-17Target: 186Updated: 2024-05-21
DASSOH - Systematic use of DDAVP to prevent serum sodium overcorrection in severe hyponatremia : a multicenter open-label randomized controlled trial
RecruitingCTIS2023-507254-32-00
Assistance Publique Hopitaux De ParisSevere hyponatremia and a high risk of rapid SNa overcorrection
Start: 2024-12-17Target: 260Updated: 2025-10-24
Intrathecal Administration of MELPIDA For Hereditary Spastic Paraplegia Type 50 (SPG50): A multicenter Phase 3, Open-Label Trial with Matched Prospective Concurrent Control Arm (CT-MEL-03)
Not yet recruitingCTIS2025-524576-28-00
Elpida Therapeutics SPCHereditary Spastic Paraplegia Type 50 (SPG50)
Target: 12Updated: 2026-07-17

Phase 4

Unknown Phase

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