extended release niacin

DRUG8 trials

Conditions

Alzheimer DiseaseAortic Stenosis and Lipoprotein(a) LevelsAtherosclerosisCardiovascular DiseasesCerebrovascular AccidentCoronary DiseaseDiabetes Mellitus, Type 2Dyslipidemia

Early Phase 1

Early Aortic Valve Lipoprotein(a) Lowering Trial

WithdrawnNCT02109614

George ThanassoulisAortic Stenosis and Lipoprotein(a) Levels

Start: 2014-05-31End: 2017-09-30Updated: 2023-10-25

Phase 1

Nicotinic Acid for the Treatment of Alzheimer's Disease

RecruitingNCT06582706

Indiana UniversityAlzheimer Disease

Start: 2024-12-19End: 2026-12-01Target: 30Updated: 2026-03-05

Phase 2

Pharmacokinetic Drug Interactions of AEGR-733 on Lipid-lowering Agents

CompletedNCT00359281

Aegerion Pharmaceuticals, Inc.Healthy

Start: 2006-03-31End: 2007-11-30Updated: 2018-02-23

Phase 3

Study of the Use of Niaspan for Treatment of Dyslipidemia in Diabetic Nephropathy

TerminatedNCT00108485

University of MiamiDiabetes Mellitus, Type 2, Hyperlipidemia, Kidney Failure, Chronic

Start: 2005-04-30End: 2012-12-31Updated: 2016-06-22

Niacin Plus Statin to Prevent Vascular Events

TerminatedNCT00120289

Axio Research. LLCAtherosclerosis, Cardiovascular Diseases, Cerebrovascular Accident +3

Start: 2005-09-30End: 2012-12-31Updated: 2016-04-06

Phase 4

Niacin, N-3 Fatty Acids and Insulin Resistance

CompletedNCT00286234

University of South DakotaHypertriglyceridemia, Metabolic Syndrome

Start: 2007-10-31End: 2008-12-31Updated: 2021-10-26

Comparative Study of the Effect of Ezetimibe Versus Extended-Release Niacin on Atherosclerosis

TerminatedNCT00397657

Walter Reed Army Medical CenterAtherosclerosis

Start: 2006-11-30End: 2009-10-31Target: 400Updated: 2009-06-17

Unknown Phase

Study of Niacin on Endothelial Function in HIV-infected Subjects With Low High Density Lipoprotein Cholesterol Levels

CompletedNCT00986986

University of HawaiiDyslipidemia, Endothelial Dysfunction, HIV Infections

Start: 2007-11-30End: 2010-04-30Updated: 2012-12-18

Arteriosclerosis Thrombosis and Vascular Biology2021-06-1733 citations

Genetic Variants Associated With Plasma Lipids Are Associated With the Lipid Response to Niacin

Journal of the American Heart Association2018-09-3014 citations

Longer duration of statin therapy is associated with decreased carotid plaque vascularity by magnetic resonance imaging.

2015-12-0122 citations

Relationship of lipoproteins to cardiovascular events: the AIM-HIGH Trial (Atherothrombosis Intervention in Metabolic Syndrome With Low HDL/High Triglycerides and Impact on Global Health Outcomes).

2013-07-31113 citations

Extended-Release Niacin Therapy and Risk of Ischemic Stroke in Patients With Cardiovascular Disease

Stroke2013-07-2438 citations

Paradoxical progression of atherosclerosis related to low-density lipoprotein reduction and exposure to ezetimibe.

2012-05-077 citations

Niacin in patients with low HDL cholesterol levels receiving intensive statin therapy.

2011-11-152036 citations

The ARBITER 6-HALTS Trial (Arterial Biology for the Investigation of the Treatment Effects of Reducing Cholesterol 6-HDL and LDL Treatment Strategies in Atherosclerosis): final results and the impact of medication adherence, dose, and treatment duration.

2010-06-01150 citations

Extended-release niacin or ezetimibe and carotid intima-media thickness.

2009-11-15442 citations