Experimental Drug,Active Comparator Device

5 trials

Sponsors

Taksin fund research, International Bio Service, Division of Dermatology, Department of medicine, Faculty of Medicine, Ramathibodi hospital, Nakornping Hospital, Nakornping Hospital, Chiang Mai, Thailand

Conditions

Healthy Thai Volunteers Healthy Thai VolunteersPain Delayed wound healing Infection Scarring Split-thickness skin graft donor sites. Split thickness skin graft Donor site Wound healing Pain management Tranexamic acid Adrenaline Bupivacaine Hydrogel Silver dressing Randomized controlled trialParticipants who desired to treat the striae microneedle radiofrequency, hyaluronic acid, striaeSplit-thickness skin graft donor site wounds are a common concern in reconstructive surgery, often associated with severe pain, delayed wound healing, and scarring. These wounds occur in patients undergoing skin grafting for burns, traumatic injuries, chronic ulcers, or surgical reconstruction. Effective management is essential to reduce pain, promote faster healing, and improve scar quality. Current treatments, such as paraffin-chlorhexidine gauze dressings, have limitations, including poor paiparticipant conditions : healthy participant 18-75 year old with myofascial pain syndrome at trapezius muscle participant conditions : healthy participant 18-75 year old with myofascial pain syndrome at trapezius muscle

Phase 1

A Single Dose, Randomized, Open-label, Two-way Crossover Bioequivalence Study of Generic Silodosin 4 mg Film-coated Tablets and Reference Product (Urief) in Healthy Thai Male Volunteers under Fed Conditions

Active, not recruitingTCTR20220722002

International Bio ServiceHealthy Thai Volunteers Healthy Thai Volunteers

Start: 2022-10-01Target: 58Updated: 2026-08-03

Phase 2

A Study of Combined Microneedle Radiofrequency with Poly D, L Lactic Acid Filler for The Treatment of striae: a randomized-controlled trial

TCTR20250115003

Division of Dermatology, Department of medicine, Faculty of Medicine, Ramathibodi hospitalParticipants who desired to treat the striae microneedle radiofrequency, hyaluronic acid, striae

Start: 2024-09-06Target: 15Updated: 2026-08-03

Topical Tranexamic Acid, Adrenaline, and Bupivacaine Solution for Pain Management and Healing in Split-Thickness Skin Graft Donor Sites: An Open-Label Interventional Study with Randomized Side Allocation

Active, not recruitingTCTR20250208007

Nakornping HospitalSplit-thickness skin graft donor site wounds are a common concern in reconstructive surgery, often associated with severe pain, delayed wound healing, and scarring. These wounds occur in patients undergoing skin grafting for burns, traumatic injuries, chronic ulcers, or surgical reconstruction. Effective management is essential to reduce pain, promote faster healing, and improve scar quality. Current treatments, such as paraffin-chlorhexidine gauze dressings, have limitations, including poor pai

Start: 2023-05-23Target: 12Updated: 2026-08-03

Efficacy of Tranexamic Acid-Adrenaline-Bupivacaine Hydrogel versus Silver-Containing Foam Dressing in the Treatment of Split-Thickness Skin Graft Donor Sites

RecruitingTCTR20250417004

Nakornping Hospital, Chiang Mai, ThailandPain Delayed wound healing Infection Scarring Split-thickness skin graft donor sites. Split thickness skin graft Donor site Wound healing Pain management Tranexamic acid Adrenaline Bupivacaine Hydrogel Silver dressing Randomized controlled trial

Start: 2025-04-16Target: 20Updated: 2026-08-03

Phase 3

Comparison of the efficacy between diclofenac phonophoresis and ultrasound therapy in myofascial pain syndrome

RecruitingTCTR20210319004

Taksin fund researchparticipant conditions : healthy participant 18-75 year old with myofascial pain syndrome at trapezius muscle participant conditions : healthy participant 18-75 year old with myofascial pain syndrome at trapezius muscle

Start: 2020-11-19Target: 52Updated: 2026-08-03