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Cyclophosphamide 500 mg Powder for Solution for Injection or Infusion

DRUG11 trials

Sponsors

GPOH gGmbH, Institut Curie, Institut Curie, Allogene Therapeutics Inc., Autolus Limited, Kite Pharma Inc.

Conditions

ANCA VasculitisB-cell Acute Lymphoblastic Leukemia (B ALL) and Aggressive Mature B-cell Non-Hodgkin Lymphoma (B NHL).Early and metastatic triple negative breast cancerFramework for OptimizingLarge B-Cell Lymphoma (LBCL)Newly diagnosed with an intracranial or spinal ependymoma (all WHO grades) including ependymoma variants: cellularPeripheral T-cell LymphomaRefining

Phase 1

Phase 2

"SKYLINE": Tiragolumab and atezolizumab associated with chemotherapy in triple negative breast cancer: A phase II trial
RecruitingCTIS2022-501561-51-00
Institut Curie, Institut CurieEarly and metastatic triple negative breast cancer
Start: 2024-03-27Target: 160Updated: 2025-05-07
A Single-Arm, Open-Label, Phase 1/2 Study Evaluating the Safety, Efficacy, and Cellular Kinetics/Pharmacodynamics of ALLO-501A, an Anti-CD19 Allogeneic CAR T Cell Therapy, and ALLO-647, an Anti-CD52 Monoclonal Antibody, in Subjects with Relapsed/Refractory Large B Cell Lymphoma (LBCL).
CompletedCTIS2022-501927-25-00
Allogene Therapeutics Inc.Large B-Cell Lymphoma (LBCL)
Start: 2023-09-29End: 2024-01-12Target: 35Updated: 2024-01-15
A Randomized, Open-Label, Phase 2 Study Evaluating Lymphodepletion With Fludarabine, Cyclophosphamide, And ALLO-647, Vs. Fludarabine And Cyclophosphamide Alone, In Subjects With Relapsed/Refractory Large B-Cell Lymphoma (LBCL) Receiving ALLO-501A Allogeneic CAR T Cell Therapy
CompletedCTIS2023-503830-27-00
Allogene Therapeutics Inc.Large B-Cell Lymphoma (LBCL)
Start: 2023-10-17End: 2024-10-28Target: 35Updated: 2024-01-29
C5691004 _ A dual-cohort, open-label, phase 2 study of brentuximab vedotin and CHP (A+CHP) in the frontline treatment of subjects with peripheral T-cell lymphoma (PTCL) with less than 10% CD30 expression
CompletedCTIS2023-509155-14-00
Seagen Inc.Peripheral T-cell Lymphoma
Start: 2021-06-10End: 2026-01-05Target: 69Updated: 2026-01-16
A Phase 2 Multicenter Study Evaluating the Efficacy of KTE-X19 in Subjects with Relapsed/Refractory Mantle Cell Lymphoma (ZUMA-2)
CompletedCTIS2023-506641-35-00
Kite Pharma Inc.Relapsed/Refractory Mantle Cell Lymphoma
Start: 2018-07-09End: 2025-06-17Target: 68Updated: 2025-03-10
SIOP Ependymoma Program II: An International Clinical Program for the diagnosis and treatment of children, adolescents and young adults with ependymoma
RecruitingCTIS2024-512222-28-00
Centre Leon Berardclear-cell and tanycytic or anaplastic ependymoma., myxopapillary, Newly diagnosed with an intracranial or spinal ependymoma (all WHO grades) including ependymoma variants: cellular +1
Start: 2015-06-02Target: 876Updated: 2024-12-09
Framework for Optimizing, Refining, and Unifying Management of HSCT in Pediatric ALL.
RecruitingCTIS2025-522052-13-00
Ospedale Pediatrico Bambino Gesuand Unifying Management of HSCT in Pediatric ALL, Framework for Optimizing, Refining
Start: 2025-12-24Target: 735Updated: 2025-11-24
A SINGLE-ARM, OPEN-LABEL, PHASE II STUDY TO DETERMINE THE SAFETY AND EFFICACY OF OBECABTAGENE AUTOLEUCEL (OBE-CEL) IN PARTICIPANTS WITH SEVERE, REFRACTORY SYSTEMIC LUPUS ERYTHEMATOSUS WITH ACTIVE LUPUS NEPHRITIS
Not yet recruitingCTIS2024-519941-32-00
Autolus LimitedSystemic Lupus Erythematosus with Active Lupus Nephritis
Target: 3Updated: 2025-11-20

Phase 3

Phase 4