core decompression

PROCEDURE13 trials

Sponsors

UCSF Benioff Children's Hospital Oakland, Erasme University Hospital, Guangdong Provincial People's Hospital, Istituto Ortopedico Rizzoli, BG Trauma Center Ludwigshafen

Conditions

AVNAvascular Necrosis of BoneAvascular Necrosis of Femur HeadAvascular Necrosis of the Femoral HeadBone Avascular NecrosisBone Marrow EdemaFemoral Neck FractureNecrosis

Phase 1

Treatment of Osteonecrosis of the Femoral Head by Bone Marrow Transplantation

CompletedNCT00821470

Erasme University HospitalNecrosis

Start: 1999-01-31End: 2008-09-30Updated: 2020-02-28

The Study of Early Stage Osteonecrosis of Femoral Head With Human Umbilical Cord Mesenchymal Stem Cells (19#iSCLife®-ONFH)

SuspendedNCT03180463

Sclnow Biotechnology Co., Ltd.Osteonecrosis of Femoral Head

Start: 2025-12-31End: 2026-12-31Target: 30Updated: 2025-05-14

Core Decompression With or Without Cement Packing for ONFH

CompletedNCT04233125

University of MinnesotaOsteonecrosis

Start: 1997-01-01End: 2008-01-01Updated: 2020-01-18

Phase 2

Implantation of Bone Marrow Cells to Treat Avascular Necrosis of Femoral Head (ANFH)

Guangdong Provincial People's HospitalAvascular Necrosis of Femur Head

Start: 2009-03-31End: 2012-12-31Target: 60Updated: 2012-08-14

Phase 3

Randomized Clinical Trial for the Treatment of Osteonecrosis of the Femoral Head

CompletedNCT01892514

Istituto Ortopedico RizzoliOsteonecrosis

Start: 2013-04-30End: 2018-04-30Target: 104Updated: 2023-05-12

Phase 4

Study for the Treatment of the Bone Marrow Edema:Core Decompression VS Bone Marrow Concentrate (BMC) VS Bone Substitute

TerminatedNCT03112122

Istituto Ortopedico RizzoliBone Marrow Edema

Start: 2016-03-11End: 2017-12-31Updated: 2018-08-09

Unknown Phase

Decompression Coring Versus Conservative Therapy in Patients With Avascular Necrosis of the Hip Related to Sickle Cell Disease

CompletedNCT00006130

UCSF Benioff Children's Hospital OaklandBone Avascular Necrosis, Sickle Cell Anemia

Start: 1999-06-30Target: 50Updated: 2017-02-15

Talar Avascular Necrosis: Surgical Angiogenesis vs. Core Decompression

BG Trauma Center LudwigshafenAvascular Necrosis of Bone

Start: 2014-02-28End: 2016-11-30Target: 20Updated: 2014-11-13

Talar Avascular Necrosis: Surgical Angiogenesis vs. Core Decompression

BG Trauma Center LudwigshafenAvascular Necrosis of Bone

Start: 2014-02-28End: 2016-11-30Target: 20Updated: 2014-11-18

Porous Tantalum Rods Improve the Hip Joint Function of Patients With Avascular Necrosis of the Femoral Head

Qinghai UniversityFemoral Neck Fracture

Start: 2015-05-31End: 2017-05-31Target: 100Updated: 2016-08-24

A Novel Reconstruction Device for Osteonecrotic Femoral Head Efficacy Evaluation

CompletedNCT04103944

National Taiwan University HospitalOsteonecrosis

Start: 2014-06-01End: 2017-12-31Updated: 2019-09-26

Hyperbaric Oxygen Therapy Versus Core Decompression Augmented With Bone Substitute in Pre Collapse of Avascular Necrosis of Femoral Head

CompletedNCT04657653

Hamad Medical CorporationAVN

Start: 2017-09-13End: 2020-03-31Updated: 2020-12-10

Autologous Bone Marrow Aspirate Treatment for Early-Stage Osteonecrosis

RecruitingNCT06123481

Johns Hopkins UniversityAvascular Necrosis of the Femoral Head, Osteonecrosis of the Femoral Head

Start: 2025-04-01End: 2029-07-31Target: 192Updated: 2025-11-26

Related Papers

10-year follow-up results of the prospective, double-blinded, randomized, controlled study on autologous bone marrow buffy coat grafting combined with core decompression in patients with avascular necrosis of the femoral head.

2020-07-1627 citations

Porous tantalum rods improve the hip joint function of patients with avascular necrosis of the femoral head after femoral neck fracture surgery: study protocol of a randomized controlled trial

Clinical and translational orthopedics2016-01-01

Efficacy of autologous bone marrow buffy coat grafting combined with core decompression in patients with avascular necrosis of femoral head: a prospective, double-blinded, randomized, controlled study.

2014-10-1476 citations