control group:control-treatment group (CPT) group: supragingival mechanical scaling and polishing. Other necessary periodontal treatments will be perfected at the end of the trial.

A Multicenter Randomized Clinical Trial to Evaluate the Effect of Non-surgical Periodontal Therapy on Clinical Parameters in Subjects with Rheumatoid arthritis and severe Periodontitis

The effect of periodontal therapy on methylation age and inflammatory age: a randomized controlled trial