Control group:Chemoradiotherapy

12 trials

Sponsors

The Second Affiliated Hospital of Xi'an Jiaotong University, Red Cross Hosptical of Yulin, Shandong Academy of Medical Sciences, Fudan University Shanghai Cancer Center, Bethune International Peace Hospital

Conditions

Cervical CancerCervical cancerEsophageal Squamous CancerEsophageal cancerEsophageal squamous cell carcinomaGastrointestinal diseasesLocal Advanced Esophageal CancerLocally advanced head and neck squamous cell carcinoma

Early Phase 1

Apatinib combined with chemotherapy or concurrent chemoradiotherapy in patients with recurrent or advanced cervical cancer: a phase II, randomized controlled trial

Active, not recruitingChiCTR1900024143

Shandong Academy of Medical SciencesCervical Cancer

Start: 2016-07-01Updated: 2019-07-01

Dihydroartemisinin combined with Chemoradiotherapy in the treatment of locally advanced head and neck squamous cell carcinoma: a multicenter, open-label, randomized, control study

RecruitingChiCTR2100041652

Bethune International Peace HospitalLocally advanced head and neck squamous cell carcinoma

Start: 2021-01-01Updated: 2021-03-22

Randomized, double-blind, phase III study comparing nituzumab combined with chemoradiotherapy versus chemoradiotherapy alone in locally advanced hypopharyngeal squamous cell carcinoma

RecruitingChiCTR2100043851

Harbin Medical University Affiliated Tumor Hospitalsquamous cell carcinoma of the hypopharynx

Start: 2021-03-03Updated: 2021-07-05

An observational real world study for comparison of the effect and safety of SintilimabInjection combined with chemotherapy versus neoadjuvant chemoradiotherapy for resectable locally advanced lymph node positive esophageal squamous cell carcinoma

Active, not recruitingChiCTR2200058565

The First Affiliated Hospital, College of Medicine, Zhejiang UniversityEsophageal Squamous Cancer

Start: 2022-06-28Updated: 2024-01-08

Phase 2

A Prospective, Multicenter, Randomized, Controlled, Phase II Study of High-dose Nimotuzumab in Combined with Chemoradiotherapy Compared with Chemoradiotherapy alone for Local Advanced Esophageal Cancer

RecruitingChiCTR-TRC-14004997

Fujian Provincial Cancer HospitalLocal Advanced Esophageal Cancer

Start: 2014-06-15Updated: 2017-04-18

Treatment of locally recurrent nasopharyngeal carcinoma with Camrelizumab combined with chemoradiotherapy: a prospective, randomized, controlled phase II clinical study

RecruitingChiCTR2000035803

Fudan University Shanghai Cancer Centernasopharyngeal carcinoma

Start: 2020-08-19Updated: 2020-08-24

Induction immunotherapy plus chemotherapy followed by definitive chemoradiotherapy versus chemoradiotherapy alone in locally advanced esophageal squamous cell carcinoma: a randomized phase II trial

Active, not recruitingChiCTR2400091065

Henan Cancer HospitalEsophageal squamous cell carcinoma

Start: 2024-10-20Updated: 2024-10-21

Phase 4

A clinical study for Endostar combined with TP regimen concurrent radiotherapy for esophageal cancer: a randomized controlled trial

RecruitingChiCTR1900021279

The Second Affiliated Hospital of Xi'an Jiaotong UniversityEsophageal cancer

Start: 2019-05-30Updated: 2019-07-15

Sintilimab combined with chemoradiotherapy for neoadjuvant treatment in patients with locally advanced rectal cancer: a single-center randomized controlled trial

Active, not recruitingChiCTR2100052288

Shandong Provincial Hospital Affiliated to Shandong First Medical UniversityGastrointestinal diseases

Start: 2021-10-25Updated: 2022-10-17

A prospective and cohort study of nimotuzumab at different gradient doses combined with concurrent chemoradiotherapy in the treatment of stage II.B-III.C of locally advanced cervical cancer

Active, not recruitingChiCTR2200066975

Chengdu Fifth People's HospitalCervical cancer

Start: 2023-01-01Updated: 2023-05-15

Unknown Phase

A randomized controlled study for Endostar combined with PF regimen concurrent radiotherapy compare with PF regimen concurrent radiotherapy for Advanced esophageal cancer

Active, not recruitingChiCTR1900022095

Red Cross Hosptical of Yulinesophageal cancer

Start: 2019-04-01Updated: 2019-03-25

PE and LEER surgical treatment of gynecologic malignant tumor recurrence of her period of preliminary study

Active, not recruitingChiCTR2200057501

Obstetrics and Gynecology Hospital of Fudan Universityadvanced and recurrent gynecological malignancies

Start: 2022-03-01Updated: 2023-10-22

Related Papers

[Comment] Total neoadjuvant treatment with short-course radiotherapy followed by sintilimab plus capecitabine-oxaliplatin versus short-course radiotherapy followed by capecitabine-oxaliplatin in patients with locally advanced rectal cancer (SPRING-01): a single-centre, open-label, phase 2, randomised controlled trial

DOAJ (DOAJ: Directory of Open Access Journals)2025-10-01

Total neoadjuvant treatment with short-course radiotherapy followed by sintilimab plus capecitabine-oxaliplatin versus short-course radiotherapy followed by capecitabine-oxaliplatin in patients with locally advanced rectal cancer (SPRING-01): a single-centre, open-label, phase 2, randomised controlled trial.

2025-07-084 citations

Short-course radiotherapy followed by sintilimab and CAPOX as total neoadjuvant treatment in locally advanced rectal cancer: A prospective, randomized controlled trial (SPRING-01).

Journal of Clinical Oncology2025-05-28

The efficacy and safety of neoadjuvant sintilimab combined with chemotherapy in resectable locally advanced lymph node-positive esophageal squamous cell carcinoma: A real world study.

Journal of Clinical Oncology2024-06-01